CCR5 is a required signaling receptor for macrophage expression of inflammatory genes in response to viral double-stranded RNA (Q91962924)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30811246%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

title

CCR5 is a required signaling receptor for macrophage expression of inflammatory genes in response to viral double-stranded RNA (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30811246%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

Zachary R Shaheen

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15 May 2020

Benjamin S Christmann

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15 May 2020

Joshua D Stafford

1 reference

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15 May 2020

Jason M Moran

1 reference

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15 May 2020

R Mark L Buller

1 reference

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15 May 2020

John A Corbett

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15 May 2020

publication date

27 February 2019

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American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

26 April 2020

published in

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15 May 2020

volume

316

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15 May 2020

issue

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15 May 2020

page(s)

R525-R534

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CCR5-Dependent Activation of mTORC1 Regulates Translation of Inducible NO Synthase and COX-2 during Encephalomyocarditis Virus Infection

15 May 2020

cites work

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23 February 2021

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23 February 2021

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The encephalomyocarditis virus

23 February 2021

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Modulatory effects of the CCR5 antagonist maraviroc on microglial pro-inflammatory activation elicited by gp120.

23 February 2021

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Ccr5 regulates inflammatory gene expression in response to encephalomyocarditis virus infection

23 February 2021

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The Role of Protein Kinase R in the Interferon Response

23 February 2021

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23 February 2021

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Activation of MDA5 requires higher-order RNA structures generated during virus infection

23 February 2021

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Differential recognition of double-stranded RNA by RIG-I-like receptors in antiviral immunity.

23 February 2021

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Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

23 February 2021

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Interferon-inducible antiviral effectors

23 February 2021

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Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages.

23 February 2021

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G-protein-coupled receptor expression, function, and signaling in macrophages

23 February 2021

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Chemokine: receptor structure, interactions, and antagonism

23 February 2021

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Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5.

23 February 2021

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Type I interferons in host defense

23 February 2021

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Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors

23 February 2021

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Role of MAPK in the regulation of double-stranded RNA- and encephalomyocarditis virus-induced cyclooxygenase-2 expression by macrophages

23 February 2021

1 reference

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Interaction between the CCR5 chemokine receptors and microbial HSP70

23 February 2021

1 reference

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Biology of CCR5 and its role in HIV infection and treatment

23 February 2021

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Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling

23 February 2021

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Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses

23 February 2021

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Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

23 February 2021

1 reference

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The specific and essential role of MAVS in antiviral innate immune responses

23 February 2021

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

23 February 2021

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The Src kinase Lyn is required for CCR5 signaling in response to MIP-1beta and R5 HIV-1 gp120 in human macrophages

23 February 2021

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A pathway analysis of poly(I:C)-induced global gene expression change in human peripheral blood mononuclear cells

23 February 2021

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CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection

23 February 2021

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Encephalomyocarditis virus induces PKR-independent mitogen-activated protein kinase activation in macrophages

23 February 2021

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Genetic and pharmacologic evidence that calcium-independent phospholipase A2beta regulates virus-induced inducible nitric-oxide synthase expression by macrophages

23 February 2021

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Toll-like receptor 3 promotes cross-priming to virus-infected cells.

23 February 2021

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The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

23 February 2021

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Chemokine receptor CCR5: insights into structure, function, and regulation

23 February 2021

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

23 February 2021

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Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors

23 February 2021

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Subcellular localization of Toll-like receptor 3 in human dendritic cells

23 February 2021

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Calcium-independent phospholipase A2 mediates CREB phosphorylation in double-stranded RNA-stimulated endothelial cells

23 February 2021

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ERK activation is required for double-stranded RNA- and virus-induced interleukin-1 expression by macrophages

23 February 2021

1 reference

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Regulation of cyclooxygenase-2 expression by macrophages in response to double-stranded RNA and viral infection

23 February 2021

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G-protein-coupled receptor oligomerization and its potential for drug discovery

23 February 2021

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Novel role for calcium-independent phospholipase A(2) in the macrophage antiviral response of inducible nitric-oxide synthase expression

23 February 2021

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mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties

23 February 2021

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

23 February 2021

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Activation of NF-kappaB by double-stranded RNA (dsRNA) in the absence of protein kinase R and RNase L demonstrates the existence of two separate dsRNA-triggered antiviral programs

23 February 2021

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Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

23 February 2021

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Potential role of PKR in double-stranded RNA-induced macrophage activation

23 February 2021

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Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways.

23 February 2021

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Inhibitory role of the host apoptogenic gene PKR in the establishment of persistent infection by encephalomyocarditis virus in U937 cells

23 February 2021

1 reference

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Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor

23 February 2021

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Double-stranded RNA-induced inducible nitric-oxide synthase expression and interleukin-1 release by murine macrophages requires NF-kappaB activation

23 February 2021

1 reference

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Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

23 February 2021

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A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR.

23 February 2021

1 reference

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CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

23 February 2021

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Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha

23 February 2021

1 reference

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CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

23 February 2021

1 reference

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Identification of a major co-receptor for primary isolates of HIV-1

23 February 2021

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Molecular cloning and functional expression of a new human CC-chemokine receptor gene

23 February 2021

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When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA.

23 February 2021

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Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system

23 February 2021

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Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes

23 February 2021

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Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease

23 February 2021

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Regulation of biosynthesis of nitric oxide.

23 February 2021

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Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

23 February 2021

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23 February 2021

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

23 February 2021

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10.1152/AJPREGU.00019.2019

23 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6589596&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6589596&resulttype=core&format=json

15 May 2020

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