Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages. (Q36644832)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18453587%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages (English)

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6 January 2020

1 reference

1 reference

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6 January 2020

Ricky Cheung

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6 January 2020

Vipa Ravyn

series ordinal

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6 January 2020

Lingshu Wang

series ordinal

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6 January 2020

Andrzej Ptasznik

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6 January 2020

language of work or name

English

0 references

publication date

1 May 2008

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6 January 2020

published in

Journal of Immunology

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6 January 2020

volume

180

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6 January 2020

issue

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6 January 2020

page(s)

6675-6684

1 reference

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A novel signaling pathway for beta-adrenergic receptor-mediated activation of phosphoinositide 3-kinase in H9c2 cardiomyocytes

6 January 2020

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Opposite regulation of IL-1beta and secreted IL-1 receptor antagonist production by phosphatidylinositide-3 kinases in human monocytes activated by lipopolysaccharides or contact with T cells

30 September 2017

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Src family kinases mediate neutrophil adhesion to adherent platelets

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LTA and LPS mediated activation of protein kinases in the regulation of inflammatory cytokines expression in macrophages

30 September 2017

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Role of the pro-inflammatory cytokines TNF-alpha and IL-1beta in HIV-associated dementia

30 September 2017

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A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

30 September 2017

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The Src kinase Lyn is required for CCR5 signaling in response to MIP-1beta and R5 HIV-1 gp120 in human macrophages

30 September 2017

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CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection

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HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.

30 September 2017

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Interleukin-1 and neuronal injury

30 September 2017

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The neuropathogenesis of AIDS

30 September 2017

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CCL3, acting via the chemokine receptor CCR5, leads to independent activation of Janus kinase 2 (JAK2) and Gi proteins

30 September 2017

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Transcriptional and post-transcriptional regulation of the PKC delta gene by etoposide in L1210 murine leukemia cells: implication of PKC delta autoregulation

30 September 2017

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Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts

30 September 2017

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Interaction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the Src homology 3 domains of PSD-95 and SAP102

30 September 2017

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Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development

30 September 2017

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Neuropathology and neurodegeneration in human immunodeficiency virus infection. Pathogenesis of HIV-induced lesions of the brain, correlations with HIV-associated disorders and modifications according to treatments

30 September 2017

1 reference

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Glucose activates protein kinase C-zeta /lambda through proline-rich tyrosine kinase-2, extracellular signal-regulated kinase, and phospholipase D: a novel mechanism for activating glucose transporter translocation

30 September 2017

1 reference

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Pathways to neuronal injury and apoptosis in HIV-associated dementia.

30 September 2017

1 reference

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Dantrolene inhibition of ryanodine receptor Ca2+ release channels. Molecular mechanism and isoform selectivity

30 September 2017

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HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation

30 September 2017

1 reference

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Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk

30 September 2017

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Structure and function of phosphatidylinositol-3,4 kinase

30 September 2017

1 reference

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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

30 September 2017

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Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

30 September 2017

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The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha.

30 September 2017

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The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

30 September 2017

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Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor

30 September 2017

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Gsalpha-selective G protein antagonists

30 September 2017

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Signal Transduction Due to HIV-1 Envelope Interactions with Chemokine Receptors CXCR4 or CCR5

30 September 2017

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Lyn, a src-like tyrosine kinase

30 September 2017

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Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity

30 September 2017

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

30 September 2017

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Inflammation in AIDS and the role of the macrophage in brain pathology.

30 September 2017

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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

30 September 2017

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Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms

30 September 2017

1 reference

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Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

30 September 2017

1 reference

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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

30 September 2017

1 reference

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RANTES-activated human T lymphocytes. A role for phosphoinositide 3-kinase

30 September 2017

1 reference

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Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

30 September 2017

1 reference

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Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor.

30 September 2017

1 reference

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Infection of monocyte-derived macrophages with human immunodeficiency virus type 1 (HIV-1). Monocyte-tropic and lymphocyte-tropic strains of HIV-1 show distinctive patterns of replication in a panel of cell types

30 September 2017

1 reference

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NF-kappa B regulates IL-1 beta transcription through a consensus NF-kappa B binding site and a nonconsensus CRE-like site.

30 September 2017

1 reference

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Sorbitol activates atypical protein kinase C and GLUT4 glucose transporter translocation/glucose transport through proline-rich tyrosine kinase-2, the extracellular signal-regulated kinase pathway and phospholipase D.

30 September 2017

1 reference

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Neuronal apoptosis does not correlate with dementia in HIV infection but is related to microglial activation and axonal damage

28 June 2018

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Chemokine receptor CCR5 functionally couples to inhibitory G proteins and undergoes desensitization

28 June 2018

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AIDS dementia is associated with massive, activated HIV-1 infection and concomitant expression of several cytokines.

28 June 2018

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Increased expression of tumor necrosis factor-alpha receptors in the brains of patients with AIDS.

28 June 2018

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HIV-1 gp120 produces DNA fragmentation in the cerebral cortex of rat.

28 June 2018

1 reference

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Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

28 June 2018

1 reference

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Neocortical damage during HIV infection

28 June 2018

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Cytokine expression in the brain during the acquired immunodeficiency syndrome

28 June 2018

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Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

28 June 2018

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PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus

20 September 2018

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N-methyl-D-aspartate receptor and L-type voltage-gated Ca2+ channel activation mediate proline-rich tyrosine kinase 2 phosphorylation during cerebral ischemia in rats

20 September 2018

1 reference

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Synthesis and biological activity of N-arylpiperazine-modified analogues of KN-62, a potent antagonist of the purinergic P2X7 receptor

20 September 2018

1 reference

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Slow channel calcium inhibition blocks proinflammatory gene signaling and reduces macrophage responsiveness

20 September 2018

1 reference

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CaM kinase II-dependent activation of tyrosine kinases and ERK1/2 in vascular smooth muscle

20 September 2018

1 reference

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HIV-1 gp120 and chemokine activation of Pyk2 and mitogen-activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxin-insensitive chemokine receptor signaling

20 September 2018

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Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 4: synthesis and structure-activity relationships for 1-[N-(methyl)-N-(phenylsulfonyl)amino]-2-(phenyl)-4-(4-(N-(alkyl)-N-(benzyloxycarbonyl)amino)piperidin-1-yl)butanes

20 September 2018

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Involvement of interleukin-1beta in the mechanism of human immunodeficiency virus type 1 (HIV-1) recombinant protein gp120-induced apoptosis in the neocortex of rat.

20 September 2018

1 reference

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Cellular localization of tumor necrosis factor mRNA in neurological tissue from HIV-infected patients by combined reverse transcriptase/polymerase chain reaction in situ hybridization and immunohistochemistry

20 September 2018

1 reference

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Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in cerebrospinal fluid

20 September 2018

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GSK-3 mediates differentiation and activation of proinflammatory dendritic cells

20 September 2018

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12 December 2020

Glycogen synthase kinase-3beta inhibition attenuates the development of ischaemia/reperfusion injury of the gut

1 reference

12 December 2020

Glycogen synthase kinase-3beta inhibition attenuates the development of bleomycin-induced lung injury

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12 December 2020

Lipopolysaccharide induces activation of CD14-associated protein tyrosine kinase p53/56lyn

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12 December 2020

HIV-1 induces tumour necrosis factor and IL-1 gene expression in primary human macrophages independent of productive infection

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12 December 2020

Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-alpha and IL-1 beta production by human monocytes

1 reference

12 December 2020

fMet-Leu-Phe Stimulates Proinflammatory Cytokine Gene Expression in Human Peripheral Blood Monocytes: The Role of Phosphatidylinositol 3-Kinase

1 reference

12 December 2020

Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation

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12 December 2020

Purification of human monocytes: isolation and collection of large numbers of peripheral blood monocytes

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12 December 2020

An inducible enhancer controls the expression of the human interleukin 1 beta gene

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12 December 2020

Cellular proteins bound to immunodeficiency viruses: implications for pathogenesis and vaccines

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12 December 2020

Tyrphostin A9 inhibits calcium release-dependent phosphorylations and calcium entry via calcium release-activated channel in Jurkat T cells

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12 December 2020

10.4049/JIMMUNOL.180.10.6675

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18453587%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18453587%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

18453587

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18453587%20AND%20SRC:MED&resulttype=core&format=json