Transcriptomic Analysis Reveals Priming of The Host Antiviral Interferon Signaling Pathway by Bronchobini® Resulting in Balanced Immune Response to Rhinovirus Infection in Mouse Lung Tissue Slices (Q91856853)

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scientific article published on 07 May 2019

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English	Transcriptomic Analysis Reveals Priming of The Host Antiviral Interferon Signaling Pathway by Bronchobini® Resulting in Balanced Immune Response to Rhinovirus Infection in Mouse Lung Tissue Slices	scientific article published on 07 May 2019

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31067687%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

Transcriptomic Analysis Reveals Priming of The Host Antiviral Interferon Signaling Pathway by Bronchobini® Resulting in Balanced Immune Response to Rhinovirus Infection in Mouse Lung Tissue Slices (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31067687%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

Rhinovirus infection

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Stella Marie Reamon-Buettner

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25 April 2020

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25 April 2020

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25 April 2020

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Natalie Hirth

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25 April 2020

Helena Obernolte

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25 April 2020

Armin Braun

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25 April 2020

Jürgen Warnecke

7

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25 April 2020

Katherina Sewald

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25 April 2020

Stella Marie Reamon-Buettner

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Monika Niehof

2

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Olga Danov

4

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Sabine Wronski

9

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language of work or name

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publication date

7 May 2019

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25 April 2020

January 2019

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full work available at URL

https://www.mdpi.com/1422-0067/20/9/2242

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International Journal of Molecular Sciences

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25 April 2020

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25 April 2020

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Creative Commons Attribution 4.0 International

7 May 2019

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CCR5 is a required signaling receptor for macrophage expression of inflammatory genes in response to viral double-stranded RNA

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Rhinovirus 3C protease suppresses apoptosis and triggers caspase-independent cell death.

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NF-κB signaling in inflammation

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Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling.

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Serum IFN-γ-induced protein 10 (IP-10) as a biomarker for severity of acute respiratory infection in healthy adults

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TRAIL signaling is proinflammatory and proviral in a murine model of rhinovirus 1B infection.

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Deletion of Irf3 and Irf7 Genes in Mice Results in Altered Interferon Pathway Activation and Granulocyte-Dominated Inflammatory Responses to Influenza A Infection.

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Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation

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TLR2 Activation Limits Rhinovirus-Stimulated CXCL-10 by Attenuating IRAK-1-Dependent IL-33 Receptor Signaling in Human Bronchial Epithelial Cells.

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Toll-like receptor 2-expressing macrophages are required and sufficient for rhinovirus-induced airway inflammation.

1 reference

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Prevention and Treatment of Influenza, Influenza-Like Illness, and Common Cold by Herbal, Complementary, and Natural Therapies

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Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication

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IL-6 in inflammation, immunity, and disease

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Interleukin-6 and its receptors: a highly regulated and dynamic system

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Rhinovirus-induced macrophage cytokine expression does not require endocytosis or replication

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The common cold: potential for future prevention or cure.

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A20 in inflammation and autoimmunity

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TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection

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Functional testing of an inhalable nanoparticle based influenza vaccine using a human precision cut lung slice technique

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No exacerbation but impaired anti-viral mechanisms in a rhinovirus-chronic allergic asthma mouse model

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Human rhinoviruses

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Determination of genotoxicity by the Comet assay applied to murine precision-cut lung slices.

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Productive entry pathways of human rhinoviruses

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Defining critical roles for NF-κB p65 and type I interferon in innate immunity to rhinovirus.

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Pathogenesis of rhinovirus infection

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Visfatin/NAMPT: a multifaceted molecule with diverse roles in physiology and pathophysiology

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Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity.

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IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

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Human rhinovirus recognition in non-immune cells is mediated by Toll-like receptors and MDA-5, which trigger a synergetic pro-inflammatory immune response

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The common cold

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Epidemiology of viral respiratory infections

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Similar frequency of rhinovirus-infectible cells in upper and lower airway epithelium

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Rhinoviruses replicate effectively at lower airway temperatures

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Functional role of type I and type II interferons in antiviral defense

1 reference

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The major and minor group receptor families contain all but one human rhinovirus serotype

1 reference

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23 February 2021

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10.3390/IJMS20092242

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