Colon Cancer and Perturbations of the Sphingolipid Metabolism (Q91693306)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31801289%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

review article

3 references

4 November 2020

18 December 2020

Colon Cancer and Perturbations of the Sphingolipid Metabolism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31801289%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1 reference

2 references

4 November 2020

18 December 2020

neoplastic gene expression regulation

1 reference

4 November 2020

1 reference

18 December 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31801289%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Alois Kozubík

1 reference

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24 April 2020

Miroslav Machala

1 reference

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24 April 2020

Jan Vondráček

1 reference

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24 April 2020

Jiřina Hofmanová

1 reference

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24 April 2020

Lucie Králiková

1 reference

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24 April 2020

Josef Slavík

series ordinal

1 reference

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24 April 2020

Zuzana Tylichová

series ordinal

1 reference

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24 April 2020

Petra Ovesná

series ordinal

1 reference

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24 April 2020

publication date

30 November 2019

3 references

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24 April 2020

4 November 2020

18 December 2020

International Journal of Molecular Sciences

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31801289%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

4 November 2020

18 December 2020

1 reference

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24 April 2020

issue

1 reference

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Creative Commons Attribution

24 April 2020

2 references

4 November 2020

18 December 2020

0 references

Ceramide synthases in cancer therapy and chemoresistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase

23 February 2021

1 reference

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Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer

23 February 2021

1 reference

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Changes in lipids composition and metabolism in colorectal cancer: a review

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Glycosphingolipid metabolism in cell fate specification

23 February 2021

1 reference

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Lactosylceramide synthase β-1,4-GalT-V: A novel target for the diagnosis and therapy of human colorectal cancer

23 February 2021

1 reference

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Altered mRNA expression levels of the major components of sphingolipid metabolism, ceramide synthases and their clinical implication in colorectal cancer

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Tumor Heterogeneity in Primary Colorectal Cancer and Corresponding Metastases. Does the Apple Fall Far From the Tree?

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

LC‑MS/MS metabolome analysis detects the changes in the lipid metabolic profiles of dMMR and pMMR cells

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells.

23 February 2021

1 reference

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Lipidomic profiling links the Fanconi anemia pathway to glycosphingolipid metabolism in head and neck cancer cells.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1).

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Butyrate and docosahexaenoic acid interact in alterations of specific lipid classes in differentiating colon cancer cells

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Tumor suppressor p53 links ceramide metabolism to DNA damage response through alkaline ceramidase 2.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Sphingolipids and their metabolism in physiology and disease

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Therapeutic implications of bioactive sphingolipids: A focus on colorectal cancer

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Ceramidases, roles in sphingolipid metabolism and in health and disease

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Role of neutral ceramidase in colon cancer

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

A 19-Gene expression signature as a predictor of survival in colorectal cancer

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

High CerS5 expression levels associate with reduced patient survival and transition from apoptotic to autophagy signalling pathways in colorectal cancer

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Phospholipids as cancer biomarkers: Mass spectrometry-based analysis

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Dietary fatty acids specifically modulate phospholipid pattern in colon cells with distinct differentiation capacities

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Ceramide Synthase 6 Is a Novel Target of Methotrexate Mediating Its Antiproliferative Effect in a p53-Dependent Manner

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Increased SPHK2 Transcription of Human Colon Cancer Cells in Serum-Depleted Culture: The Involvement of CREB Transcription Factor

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Enhanced colonic tumorigenesis in alkaline sphingomyelinase (NPP7) knockout mice

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Sphingosine kinase 1 promotes malignant progression in colon cancer and independently predicts survival of patients with colon cancer by competing risk approach in South asian population

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Glycosphingolipids: synthesis and functions

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Sphingolipids in colon cancer

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Epigenetic and genetic features of 24 colon cancer cell lines

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Folate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

A shift in sphingolipid composition from C24 to C16 increases susceptibility to apoptosis in HeLa cells

23 February 2021

1 reference

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GCS overexpression is associated with multidrug resistance of human HCT-8 colon cancer cells

23 February 2021

1 reference

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Sphingosine 1-phosphate signalling in cancer

23 February 2021

1 reference

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Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth

23 February 2021

1 reference

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Chain length-specific properties of ceramides

23 February 2021

1 reference

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Ceramide synthase-dependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events

23 February 2021

1 reference

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Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance

23 February 2021

1 reference

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Sphingolipids and expression regulation of genes in cancer.

23 February 2021

1 reference

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Modeling oncogenic signaling in colon tumors by multidirectional analyses of microarray data directed for maximization of analytical reliability

23 February 2021

1 reference

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Activation of ceramide synthase 6 by celecoxib leads to a selective induction of C16:0-ceramide

23 February 2021

1 reference

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Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids

23 February 2021

1 reference

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Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients

23 February 2021

1 reference

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Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs

23 February 2021

1 reference

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Role for sphingosine kinase 1 in colon carcinogenesis.

23 February 2021

1 reference

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Plasma membrane-associated sialidase as a crucial regulator of transmembrane signalling

23 February 2021

1 reference

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Neutral sphingomyelinase-3 is a DNA damage and nongenotoxic stress-regulated gene that is deregulated in human malignancies

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Regulation of lactosylceramide synthase (glucosylceramide beta1-->4 galactosyltransferase); implication as a drug target

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

The Yin and Yang of lactosylceramide metabolism: implications in cell function

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Roles of plasma membrane-associated sialidase NEU3 in human cancers.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Sphingosine-1-phosphate metabolism and intestinal tumorigenesis: lipid signaling strikes again

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

A crucial role of plasma membrane-associated sialidase in the survival of human cancer cells

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Sphingosine kinase 1 is up-regulated in colon carcinogenesis

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Reduction in alkaline sphingomyelinase in colorectal tumorigenesis is not related to the APC gene mutation

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Sphingoid bases and ceramide induce apoptosis in HT-29 and HCT-116 human colon cancer cells.

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Modulation of intracellular beta-catenin localization and intestinal tumorigenesis in vivo and in vitro by sphingolipids

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

An oncogenic role of sphingosine kinase

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

Familial adenomatous polyposis is associated with a marked decrease in alkaline sphingomyelinase activity: a key factor to the unrestrained cell proliferation?

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6929044

WITHDRAWN: Ceramide synthases in cancer therapy and chemoresistance

23 February 2021

1 reference

3 January 2024

https://opencitations.net/index/api/v1/citations/10.1016/J.PLIPRES.2019.100992

Identifiers

DOI

10.3390/IJMS20236051

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31801289%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31801289%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

PubMed publication ID

31801289

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31801289%20AND%20SRC:MED&resulttype=core&format=json