Sphingosine 1-phosphate signalling in cancer (Q37977171)

26 August 2017

title

Sphingosine 1-phosphate signalling in cancer (English)

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26 August 2017

Nigel J Pyne

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26 August 2017

Francesca Tonelli

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26 August 2017

Keng Gat Lim

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26 August 2017

Jaclyn S Long

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26 August 2017

Joanne Edwards

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26 August 2017

Susan Pyne

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26 August 2017

publication date

1 February 2012

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Biochemical Society Transactions

26 August 2017

published in

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26 August 2017

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26 August 2017

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26 August 2017

page(s)

94-100

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Sphingosine 1-phosphate signalling in mammalian cells

26 August 2017

cites work

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Sphingosine 1-phosphate and cancer

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Sphingosine kinase 1 induces tolerance to human epidermal growth factor receptor 2 and prevents formation of a migratory phenotype in response to sphingosine 1-phosphate in estrogen receptor-positive breast cancer cells

21 January 2018

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High Expression of Sphingosine 1-Phosphate Receptors, S1P1 and S1P3, Sphingosine Kinase 1, and Extracellular Signal-Regulated Kinase-1/2 Is Associated with Development of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Patients

21 January 2018

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Sliding p21-activated kinase 1 to nucleus impacts tamoxifen sensitivity.

21 January 2018

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Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer

21 January 2018

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Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

21 January 2018

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FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells

21 January 2018

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A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia.

21 January 2018

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The Sphingosine Kinase 1 Inhibitor 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole Induces Proteasomal Degradation of Sphingosine Kinase 1 in Mammalian Cells

21 January 2018

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FTY720 analogues as sphingosine kinase 1 inhibitors: enzyme inhibition kinetics, allosterism, proteasomal degradation, and actin rearrangement in MCF-7 breast cancer cells

21 January 2018

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(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity

21 January 2018

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Ceramide synthesis is modulated by the sphingosine analog FTY720 via a mixture of uncompetitive and noncompetitive inhibition in an Acyl-CoA chain length-dependent manner

21 January 2018

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Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their function.

21 January 2018

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Gilenya (FTY720) inhibits acid sphingomyelinase by a mechanism similar to tricyclic antidepressants

21 January 2018

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The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors

21 January 2018

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Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells

21 January 2018

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High expression of sphingosine kinase 1 and S1P receptors in chemotherapy-resistant prostate cancer PC3 cells and their camptothecin-induced up-regulation

21 January 2018

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Chemosensitizing effects of sphingosine kinase-1 inhibition in prostate cancer cell and animal models.

21 January 2018

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Expression profiling the temperature-dependent amphibian response to infection by Batrachochytrium dendrobatidis

21 January 2018

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Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models

21 January 2018

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Mouse sphingosine kinase isoforms SPHK1a and SPHK1b differ in enzymatic traits including stability, localization, modification, and oligomerization

21 January 2018

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S1P(2) receptors mediate inhibition of glioma cell migration through Rho signaling pathways independent of PTEN.

21 January 2018

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Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling

21 January 2018

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Sphingosine 1-phosphate receptor expression profile in human gastric cancer cells: differential regulation on the migration and proliferation.

21 January 2018

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Targeted disruption of the S1P2 sphingosine 1-phosphate receptor gene leads to diffuse large B-cell lymphoma formation

21 January 2018

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Tethering of the platelet-derived growth factor beta receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells

21 January 2018

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c-Src is involved in regulating signal transmission from PDGFbeta receptor-GPCR(s) complexes in mammalian cells

21 January 2018

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Sphingosine 1-phosphate and platelet-derived growth factor (PDGF) act via PDGF beta receptor-sphingosine 1-phosphate receptor complexes in airway smooth muscle cells

21 January 2018

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An oncogenic role of sphingosine kinase

21 January 2018

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Guanine nucleotides regulate sphingosine kinase 1 activation by eukaryotic elongation factor 1A and provide a mechanism for eEF1A-associated oncogenesis

21 January 2018

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Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20110602

Lysophospholipids transactivate HER2/neu (erbB-2) in human gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110602

Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110602

A molecular signature of metastasis in primary solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110602

Differential gene expression in ovarian carcinoma: identification of potential biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110602

High-resolution mapping of genomic imbalance and identification of gene expression profiles associated with differential chemotherapy response in serous epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110602

Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110602

Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20110602

21 January 2018

Identifiers

DOI

10.1042/BST20110602

1 reference

26 August 2017

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