Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients (Q90481562)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32194829%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

title

Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients (English)

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14 April 2020

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14 April 2020

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14 April 2020

Jacques Pouysségur

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14 April 2020

Maeva Dufies

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14 April 2020

Sandra Lacas-Gervais

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14 April 2020

Baharia Mograbi

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14 April 2020

Nirvana Sadaghianloo

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14 April 2020

Julien Parola

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14 April 2020

Lucilla Fabbri

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14 April 2020

Betty Gardie

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14 April 2020

Sophie Gad-Lapiteau

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14 April 2020

Nicolas Nottet

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14 April 2020

Monique Meyenberg Cunha de Padua

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14 April 2020

Julie Contenti

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14 April 2020

Delphine Borchiellini

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14 April 2020

Jean-Marc Ferrero

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14 April 2020

Nathalie Rioux Leclercq

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14 April 2020

Damien Ambrosetti

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14 April 2020

Stéphane Richard

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14 April 2020

Julien Viotti

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14 April 2020

Emmanuel Chamorey

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14 April 2020

William J Craigen

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14 April 2020

Bernard Mari

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14 April 2020

Stéphan Clavel

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14 April 2020

Gilles Pagès

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14 April 2020

Nathalie M Mazure

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publication date

3 February 2020

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14 April 2020

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14 April 2020

volume

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issue

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14 April 2020

page(s)

2696-2713

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describes a project that uses

14 April 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

Structure and mode of action of a voltage dependent anion-selective channel (VDAC) located in the outer mitochondrial membrane

1 reference

12 December 2020

Control of Cell Pattern in the Neural Tube by the Zinc Finger Transcription Factor and Oncogene Gli-1

1 reference

12 December 2020

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

1 reference

12 December 2020

Gli proteins encode context-dependent positive and negative functions: implications for development and disease

1 reference

12 December 2020

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

1 reference

12 December 2020

HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation

1 reference

12 December 2020

Oligomeric states of the voltage-dependent anion channel and cytochrome c release from mitochondria

1 reference

12 December 2020

Mammalian target of rapamycin

1 reference

12 December 2020

Voltage-dependent anion channel (VDAC) as mitochondrial governator--thinking outside the box

1 reference

12 December 2020

The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha

1 reference

12 December 2020

The Ciliopathies: An Emerging Class of Human Genetic Disorders

1 reference

12 December 2020

Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein

1 reference

12 December 2020

The primary cilium in cell signaling and cancer

1 reference

12 December 2020

Determination of the conformation of the human VDAC1 N-terminal peptide, a protein moiety essential for the functional properties of the pore

1 reference

12 December 2020

Von hippel-lindau: a tumor suppressor links microtubules to ciliogenesis and cancer development

1 reference

12 December 2020

The VHL tumor suppressor: riding tandem with GSK3beta in primary cilium maintenance.

1 reference

12 December 2020

When cilia go bad: cilia defects and ciliopathies

1 reference

12 December 2020

Cell cycle-dependent ciliogenesis and cancer

1 reference

12 December 2020

Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

1 reference

12 December 2020

Regulation of hexokinase binding to VDAC

1 reference

12 December 2020

Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.

1 reference

12 December 2020

The vertebrate primary cilium in development, homeostasis, and disease

1 reference

12 December 2020

The primary cilium as a complex signaling center

1 reference

12 December 2020

Hypoxic enlarged mitochondria protect cancer cells from apoptotic stimuli

1 reference

12 December 2020

Targeting mitochondria as a therapeutic target in cancer

1 reference

12 December 2020

Expression of a truncated active form of VDAC1 in lung cancer associates with hypoxic cell survival and correlates with progression to chemotherapy resistance

1 reference

12 December 2020

Molecular pathways: the role of primary cilia in cancer progression and therapeutics with a focus on Hedgehog signaling

1 reference

12 December 2020

Von Hippel-Lindau: how a rare disease illuminates cancer biology

1 reference

12 December 2020

VDAC3 regulates centriole assembly by targeting Mps1 to centrosomes

1 reference

12 December 2020

Voltage-dependent anion channels modulate mitochondrial metabolism in cancer cells: regulation by free tubulin and erastin

1 reference

12 December 2020

The primary cilium: guardian of organ development and homeostasis

1 reference

12 December 2020

Novel clinical therapeutics targeting the epithelial to mesenchymal transition

1 reference

12 December 2020

Local mitochondrial-endolysosomal microfusion cleaves voltage-dependent anion channel 1 to promote survival in hypoxia

1 reference

12 December 2020

Primary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma

1 reference

12 December 2020

Targeting hypoxia at the forefront of anticancer immune responses

1 reference

12 December 2020

Non-Overlapping Distributions and Functions of the VDAC Family in Ciliogenesis

1 reference

12 December 2020

Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation

1 reference

12 December 2020

Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma

1 reference

12 December 2020

The cilia-regulated proteasome and its role in the development of ciliopathies and cancer

1 reference

12 December 2020

Cancer in patients with inherited ciliopathies: polycystic kidney disease.

1 reference

12 December 2020

GeneSCF: a real-time based functional enrichment tool with support for multiple organisms

1 reference

12 December 2020

Mortalin-mediated and ERK-controlled targeting of HIF-1α to mitochondria confers resistance to apoptosis under hypoxia

1 reference

12 December 2020

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade.

1 reference

12 December 2020

The Mitochondrial Voltage-Dependent Anion Channel 1, Ca2+ Transport, Apoptosis, and Their Regulation

1 reference

12 December 2020

Metabolic reprogramming and epithelial-to-mesenchymal transition in cancer

1 reference

12 December 2020

Aberrant cancer metabolism in epithelial-mesenchymal transition and cancer metastasis: Mechanisms in cancer progression

1 reference

12 December 2020

Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells

1 reference

12 December 2020

Commentary on: "An integrated metabolic atlas of clear cell renal cell carcinoma." Hakimi AA, Reznik E, Lee CH, Creighton CJ, Brannon AR, Luna A, Aksoy BA, Liu EM, Shen R, Lee W, Chen Y, Stirdivant SM, Russo P, Chen YB, Tickoo SK, Reuter VE, Cheng E

1 reference

12 December 2020

Voltage-Dependent Anion Channel 1 As an Emerging Drug Target for Novel Anti-Cancer Therapeutics

1 reference

12 December 2020

Editorial: Uncovering the Function of the Mitochondrial Protein VDAC in Health and Disease: From Structure-Function to Novel Therapeutic Strategies

1 reference

12 December 2020

The two glycolytic markers GLUT1 and MCT1 correlate with tumor grade and survival in clear-cell renal cell carcinoma

1 reference

12 December 2020

Hypoxic-induced truncation of voltage-dependent anion channel 1 is mediated by both asparagine endopeptidase and calpain 1 activities

1 reference

12 December 2020

Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation.

1 reference

12 December 2020

Soluble CD146 is a predictive marker of pejorative evolution and of sunitinib efficacy in clear cell renal cell carcinoma.

1 reference

12 December 2020

Chick chorioallantoic membrane assay as an in vivo model to study the effect of nanoparticle-based anticancer drugs in ovarian cancer.

1 reference

12 December 2020

Regulation of PD-L1: Emerging Routes for Targeting Tumor Immune Evasion.

1 reference

12 December 2020

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

1 reference

12 December 2020

Integrative analysis of dysregulated microRNAs and mRNAs in multiple recurrent synchronized renal tumors from patients with von Hippel-Lindau disease

1 reference

12 December 2020

VEGFC acts as a double-edged sword in renal cell carcinoma aggressiveness

1 reference

12 December 2020

Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5

1 reference

12 December 2020

Primary Cilium in Cancer Hallmarks

1 reference

12 December 2020

New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments

1 reference

12 December 2020

DNA methylation-regulated QPCT promotes sunitinib resistance by increasing HRAS stability in renal cell carcinoma

1 reference

12 December 2020

Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.7150/THNO.41001

1 reference

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14 April 2020

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14 April 2020

PubMed publication ID

32194829

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