Mechanically-Loaded Breast Cancer Cells Modify Osteocyte Mechanosensitivity by Secreting Factors That Increase Osteocyte Dendrite Formation and Downstream Resorption (Q90401265)

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scientific article published on 03 July 2018

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English	Mechanically-Loaded Breast Cancer Cells Modify Osteocyte Mechanosensitivity by Secreting Factors That Increase Osteocyte Dendrite Formation and Downstream Resorption	scientific article published on 03 July 2018

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30034365%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Mechanically-Loaded Breast Cancer Cells Modify Osteocyte Mechanosensitivity by Secreting Factors That Increase Osteocyte Dendrite Formation and Downstream Resorption (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30034365%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

author name string

Wenbo Wang

1

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13 April 2020

Blayne A Sarazin

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30034365%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Gabriel Kornilowicz

3

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Europe PubMed Central

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13 April 2020

Maureen E Lynch

4

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13 April 2020

publication date

3 July 2018

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13 April 2020

Frontiers in Endocrinology

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Europe PubMed Central

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13 April 2020

9

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13 April 2020

352

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13 April 2020

copyright license

Creative Commons Attribution 4.0 International

3 July 2018

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April 2022 Public Data File from Crossref

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6043807/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Establishment and characterization of an osteocyte-like cell line, MLO-Y4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

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Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of functional gap junctions and regulation by fluid flow in osteocyte-like MLO-Y4 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

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Establishment of an osteoid preosteocyte-like cell MLO-A5 that spontaneously mineralizes in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor effects of bisphosphonates

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bone microenvironment in metastasis; what is special about bone?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions of RANKL/RANK/OPG in bone modeling and remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analyzing real-time PCR data by the comparative C(T) method

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel 3-D mineralized tumor model to study breast cancer bone metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantifying fluid shear stress in a rocking culture dish

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of the transition from osteoblast to osteocyte

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metastasis and bone loss: advancing treatment and prevention.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Personalized treatment of early-stage breast cancer: present concepts and future directions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real-time measurement of solute transport within the lacunar-canalicular system of mechanically loaded bone: direct evidence for load-induced fluid flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interstitial flow influences direction of tumor cell migration through competing mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix-embedded cells control osteoclast formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated circulating sclerostin correlates with advanced disease features and abnormal bone remodeling in symptomatic myeloma: reduction post-bortezomib monotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased osteocyte death in multiple myeloma patients: role in myeloma-induced osteoclast formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanical regulation of signaling pathways in bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix production and collagen structure are enhanced in two types of osteogenic progenitor cells by a simple fluid shear stress stimulus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Load regulates bone formation and Sclerostin expression through a TGFβ-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The osteocyte: an endocrine cell ... and more

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo tibial compression decreases osteolysis and tumor formation in a human metastatic breast cancer model

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteocytes: master orchestrators of bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanosensory responses of osteocytes to physiological forces occur along processes and not cell body and require αVβ3 integrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic osteocytes and the control of targeted bone resorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanotransduction of fluid stresses governs 3D cell migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential impact of adenosine nucleotides released by osteocytes on breast cancer growth and bone metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanically stimulated bone cells secrete paracrine factors that regulate osteoprogenitor recruitment, proliferation, and differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Wnt Inhibitor Sclerostin Is Up-regulated by Mechanical Unloading in Osteocytes in Vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical models for in vitro mechanical loading of bone-derived cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructural alterations of osteocyte morphology via loaded implants in rabbit tibiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteocytic connexin hemichannels suppress breast cancer growth and bone metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low intensity vibration mitigates tumor progression and protects bone quantity and quality in a murine model of myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-Dimensional Mechanical Loading Modulates the Osteogenic Response of Mesenchymal Stem Cells to Tumor-Derived Soluble Signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role and mechanism of action of sclerostin in bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engineered Multifunctional Nanomedicine for Simultaneous Stereotactic Chemotherapy and Inhibited Osteolysis in an Orthotopic Model of Bone Metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microfluidic co-culture platform for investigating osteocyte-osteoclast signalling during fluid shear stress mechanostimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting Osteocytes to Attenuate Early Breast Cancer Bone Metastasis by Theranostic Upconversion Nanoparticles with Responsive Plumbagin Release.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Supraphysiological loading induces osteocyte-mediated osteoclastogenesis in a novel in vitro model for bone implant loosening.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-tumor effect of RANKL inhibition in malignant solid tumors - A systematic review.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30034365

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FENDO.2018.00352

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30034365%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30034365%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30034365%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

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