Transcriptional Regulation of Voltage-Gated Sodium Channels Contributes to GM-CSF-Induced Pain (Q90251219)

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12 April 2020

title

Transcriptional Regulation of Voltage-Gated Sodium Channels Contributes to GM-CSF-Induced Pain (English)

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12 April 2020

Fan Zhang

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12 April 2020

Yiying Wang

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12 April 2020

Yu Liu

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12 April 2020

Hao Han

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12 April 2020

Dandan Zhang

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12 April 2020

Xizhenzi Fan

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12 April 2020

Xiaona Du

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12 April 2020

Nikita Gamper

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12 April 2020

Hailin Zhang

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12 April 2020

publication date

23 April 2019

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12 April 2020

published in

Journal of Neuroscience

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12 April 2020

volume

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issue

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12 April 2020

page(s)

5222-5233

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Quantitative assessment of tactile allodynia in the rat paw

12 April 2020

cites work

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Inhibition of proliferation and induction of apoptosis in juvenile myelomonocytic leukemic cells by the granulocyte-macrophage colony-stimulating factor analogue E21R

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Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons.

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Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8.

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12 December 2020

GM-CSF activates the Jak/STAT pathway to rescue polymorphonuclear neutrophils from spontaneous apoptosis in young but not elderly individuals

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12 December 2020

Differential slow inactivation and use-dependent inhibition of Nav1.8 channels contribute to distinct firing properties in IB4+ and IB4- DRG neurons.

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Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable

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Hematopoietic colony–stimulating factors mediate tumor-nerve interactions and bone cancer pain

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12 December 2020

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents

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12 December 2020

The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl- channels

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12 December 2020

Bilateral downregulation of Nav1.8 in dorsal root ganglia of rats with bone cancer pain induced by inoculation with Walker 256 breast tumor cells

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12 December 2020

Granulocyte macrophage-colony stimulating factor shows anti-apoptotic activity in neural progenitor cells via JAK/STAT5-Bcl-2 pathway

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12 December 2020

Hematopoietic colony-stimulating factors: new players in tumor–nerve interactions

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12 December 2020

Deletion mutation of sodium channel Na(V)1.7 in inherited erythromelalgia: enhanced slow inactivation modulates dorsal root ganglion neuron hyperexcitability.

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12 December 2020

Cancer-induced bone pain sequentially activates the ERK/MAPK pathway in different cell types in the rat spinal cord

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Nav1.9 channel contributes to mechanical and heat pain hypersensitivity induced by subacute and chronic inflammation

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12 December 2020

Inhibition of voltage-gated Na(+) currents in sensory neurones by the sea anemone toxin APETx2.

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12 December 2020

Granulocyte-macrophage colony-stimulating factor is a key mediator in inflammatory and arthritic pain.

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12 December 2020

Granulocyte-macrophage colony-stimulating factor is a key mediator in experimental osteoarthritis pain and disease development.

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12 December 2020

Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model

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12 December 2020

Sargramostim (GM-CSF) and lenalidomide in castration-resistant prostate cancer (CRPC): results from a phase I-II clinical trial

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12 December 2020

Selective JAK/STAT3 signalling regulates transcription of colony stimulating factor-2 and -3 in Concanavalin-A-activated mesenchymal stromal cells

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12 December 2020

Transcriptional mechanisms underlying sensitization of peripheral sensory neurons by granulocyte-/granulocyte-macrophage colony stimulating factors

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12 December 2020

Pain without nociceptors? Nav1.7-independent pain mechanisms.

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12 December 2020

Gain-of-function mutations in sodium channel Na(v)1.9 in painful neuropathy

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12 December 2020

Control of somatic membrane potential in nociceptive neurons and its implications for peripheral nociceptive transmission.

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12 December 2020

Contribution of acidic extracellular microenvironment of cancer-colonized bone to bone pain

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12 December 2020

Somatosensory neuron types identified by high-coverage single-cell RNA-sequencing and functional heterogeneity

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12 December 2020

In vivo at last: Demonstrating the biological credentials and clinical potential of GM-CSF.

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12 December 2020

Stromal Cell-Derived Factor 1 Increases Tetrodotoxin-Resistant Sodium Currents Nav1.8 and Nav1.9 in Rat Dorsal Root Ganglion Neurons via Different Mechanisms

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12 December 2020

Synergistic regulation of serotonin and opioid signaling contributes to pain insensitivity in Nav1.7 knockout mice.

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12 December 2020

Local GABAergic signaling within sensory ganglia controls peripheral nociceptive transmission.

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12 December 2020

Sodium channel NaV1.9 mutations associated with insensitivity to pain dampen neuronal excitability

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12 December 2020

M-type K(+) channels in peripheral nociceptive pathways.

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12 December 2020

Phenotypic Differences in Multiple Osteochondromas in Monozygotic Twins: A Case Report

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12 December 2020

DRG Voltage-gated Sodium Channel 1.7 is Up-regulated in Paclitaxel-Induced Neuropathy in Rats and in Humans with Neuropathic Pain.

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12 December 2020

Central inhibition of granulocyte-macrophage colony-stimulating factor is analgesic in experimental neuropathic pain

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12 December 2020

Recurrent STAT3-JAK2 fusions in indolent T-cell lymphoproliferative disorder of the gastrointestinal tract.

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12 December 2020

Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

1 reference

12 December 2020

10.1523/JNEUROSCI.2204-18.2019

Identifiers

DOI

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12 April 2020

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12 April 2020

PubMed publication ID

31015342

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