Immunoadsorption enables successful rAAV5-mediated repeated hepatic gene delivery in nonhuman primates (Q90000829)

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scientific article published on 01 September 2019

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English	Immunoadsorption enables successful rAAV5-mediated repeated hepatic gene delivery in nonhuman primates	scientific article published on 01 September 2019

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Europe PubMed Central

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6737410

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10 April 2020

title

Immunoadsorption enables successful rAAV5-mediated repeated hepatic gene delivery in nonhuman primates (English)

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6737410

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10 April 2020

main subject

primate

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primates

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Harald Petry

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5

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6737410

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Gloria González Aseguinolaza

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7

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6737410

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David Salas

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1

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6737410

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Karin L Kwikkers

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2

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Nerea Zabaleta

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3

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6737410

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10 April 2020

Andrea Bazo

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4

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10 April 2020

Sander J van Deventer

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6

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6737410

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Valerie Ferreira

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8

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6737410

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publication date

1 September 2019

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10 April 2020

volume

3

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6737410

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10 April 2020

issue

17

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6737410

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10 April 2020

page(s)

2632-2641

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10 April 2020

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Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

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Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

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Plasmapheresis eliminates the negative impact of AAV antibodies on microdystrophin gene expression following vascular delivery.

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Evaluation of Readministration of a Recombinant Adeno-Associated Virus Vector Expressing Acid Alpha-Glucosidase in Pompe Disease: Preclinical to Clinical Planning

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Variability in Humoral Immunity to Measles Vaccine: New Developments

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Single point mutation in adeno-associated viral vectors -DJ capsid leads to improvement for gene delivery in vivo

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Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria

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Improvement of Adeno-Associated Virus-Mediated Liver Transduction Efficacy by Regional Administration in Macaca fascicularis.

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Successful Repeated Hepatic Gene Delivery in Mice and Non-human Primates Achieved by Sequential Administration of AAV5ch and AAV1.

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Immunoadsorption in Autoimmune Diseases Affecting the Kidney.

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Strategy to detect pre-existing immunity to AAV gene therapy.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant.

1 reference

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12 December 2020

based on heuristic

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Gene therapy with adeno-associated virus vector 5-human factor IX in adults with hemophilia B.

1 reference

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reference URL

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autologous and Heterologous Cell Therapy for Hemophilia B toward Functional Restoration of Factor IX.

1 reference

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reference URL

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12 December 2020

based on heuristic

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Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/31501158

retrieved

12 December 2020

based on heuristic

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AAV Immunogenicity: A Matter of Sensitivity

1 reference

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12 December 2020

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Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration

1 reference

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12 December 2020

based on heuristic

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Therapeutic hFIX Activity Achieved after Single AAV5-hFIX Treatment in Hemophilia B Patients and NHPs with Pre-existing Anti-AAV5 NABs

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/31501158

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12 December 2020

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Identifiers

DOI

10.1182/BLOODADVANCES.2019000380

1 reference

stated in

Europe PubMed Central

PMC publication ID

6737410

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31501158%20AND%20SRC:MED&resulttype=core&format=json

retrieved

10 April 2020

PMC publication ID

6737410

1 reference

stated in

Europe PubMed Central

PMC publication ID

6737410

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31501158%20AND%20SRC:MED&resulttype=core&format=json

retrieved

10 April 2020

PubMed publication ID

31501158

1 reference

stated in

Europe PubMed Central

PMC publication ID

6737410

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31501158%20AND%20SRC:MED&resulttype=core&format=json

retrieved

10 April 2020

 

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