Unique molecular signatures of antiviral memory CD8+ T cells associated with asymptomatic recurrent ocular herpes (Q98471389)

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19 August 2020

title

Unique molecular signatures of antiviral memory CD8+ T cells associated with asymptomatic recurrent ocular herpes (English)

1 reference

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19 August 2020

Swayam Prakash

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19 August 2020

Soumyabrata Roy

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19 August 2020

Ruchi Srivastava

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19 August 2020

Pierre-Gregoire Coulon

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19 August 2020

Nisha R Dhanushkodi

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19 August 2020

Hawa Vahed

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19 August 2020

Allen Jankeel

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19 August 2020

Roger Geertsema

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19 August 2020

Cassandra Amezquita

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19 August 2020

Lan Nguyen

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19 August 2020

Ilhem Messaoudi

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19 August 2020

Amanda M Burkhardt

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19 August 2020

Lbachir BenMohamed

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19 August 2020

publication date

14 August 2020

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19 August 2020

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19 August 2020

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19 August 2020

issue

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19 August 2020

page(s)

13843

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describes a project that uses

19 August 2020

DESeq2

object named as

DESeq2

DESeq

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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Prior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice

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Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes

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Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of l

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Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpes

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A Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a "Humanized" HLA Transgenic Rabbit Model

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HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgeni

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7 January 2021

Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocul

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7 January 2021

Unique Type I Interferon, Expansion/Survival Cytokines and JAK/STAT Gene Signatures of Multi-Functional HSV-Specific Effector Memory CD8 T Cells Are Associated with Asymptomatic Ocular Herpes in Humans

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The Herpes Simplex Virus 1 Latency-Associated Transcript Promotes Functional Exhaustion of Virus-Specific CD8 + T Cells in Latently Infected Trigeminal Ganglia: a Novel Immune Evasion Mechanism

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Early CD4(+) T cell help prevents partial CD8(+) T cell exhaustion and promotes maintenance of Herpes Simplex Virus 1 latency

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Immunization with Different Viral Antigens Alters the Pattern of T Cell Exhaustion and Latency in Herpes Simplex Virus Type 1-Infected Mice

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Blockade of LAG-3 Immune Checkpoint Combined With Therapeutic Vaccination Restore the Function of Tissue-Resident Anti-viral CD8 T Cells and Protect Against Recurrent Ocular Herpes Simplex Infection and Disease

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Rates of reactivation of latent herpes simplex virus from mouse trigeminal ganglia ex vivo correlate directly with viral load and inversely with number of infiltrating CD8+ T cells

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Blockade of PD-1 and LAG-3 Immune Checkpoints Combined with Vaccination Restores the Function of Antiviral Tissue-Resident CD8+ TRM Cells and Reduces Ocular Herpes Simplex Infection and Disease in HLA Transgenic Rabbits

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate.

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7 January 2021

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7 January 2021

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Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells.

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Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B

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Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107 CD8 T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect ag

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7 January 2021

Detection of Herpes simplex virus DNA by real-time PCR.

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