Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease (Q96946557)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

title

Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

Pelizaeus-Merzbacher disease

4 July 2020

main subject

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

H Elizabeth Shick

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Berit E Powers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Yuka Maeno-Hikichi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Mayur Madhavan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Kevin C Allan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Baraa S Nawash

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Artur S Gevorgyan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Stevephen Hung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Hannah E Olsen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Midori Hitomi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Daniela M Schlatzer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Hien T Zhao

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Adam Swayze

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

David F LePage

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Weihong Jiang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Ronald A Conlon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Frank Rigo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

publication date

1 July 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

Pelizaeus-Merzbacher Disease: Molecular and Cellular Pathologies and Associated Phenotypes

4 July 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Axonal swellings and degeneration in mice lacking the major proteolipid of myelin

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Assembly of CNS myelin in the absence of proteolipid protein

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Glial progenitor cell-based treatment and modeling of neurological disease

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Neural stem cell engraftment and myelination in the human brain

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Umbilical cord blood transplantation to treat Pelizaeus-Merzbacher Disease in 2 young boys

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Gene suppressing therapy for Pelizaeus-Merzbacher disease using artificial microRNA.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Neural stem cells restore myelin in a demyelinating model of Pelizaeus-Merzbacher disease

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Multiplex genome engineering using CRISPR/Cas systems

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Increased Plp1 Gene Expression Leads to Massive Microglial Cell Activation and Inflammation Throughout the Brain

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Rumpshaker-like proteolipid protein (PLP) ratio in a mouse model with unperturbed structural and functional integrity of the myelin sheath and axons in the central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Elevated levels of the chemokine GRO-1 correlate with elevated oligodendrocyte progenitor proliferation in the jimpy mutant

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Proteolipid protein gene mutation induces altered ventilatory response to hypoxia in the myelin-deficient rat.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Pelizaeus-Merzbacher disease can be a differential diagnosis in males presenting with severe neonatal respiratory distress and hypotonia.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Connatal Pelizaeus-Merzbacher Disease with congenital stridor in two maternal cousins

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Oligodendroglia metabolically support axons and contribute to neurodegeneration.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Acceleration of conduction velocity linked to clustering of nodal components precedes myelination.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

DNA targeting specificity of RNA-guided Cas9 nucleases

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Positive effect of partial zona-pellucida dissection on the in vitro fertilizing capacity of cryopreserved C57BL/6J transgenic mouse spermatozoa of low motility

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Integrative genomics viewer

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Universal sample preparation method for proteome analysis

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Deep learning enables de novo peptide sequencing from data-independent-acquisition mass spectrometry

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

De novo peptide sequencing by deep learning

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-2494-3

7 January 2021

10.1038/S41586-020-2494-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32610343%20AND%20SRC:MED&resulttype=core&format=json