Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR. (Q36068445)

12 August 2017

Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR. (English)

1 reference

12 August 2017

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

Sylvie Schneider-Maunoury

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Kai Schönig

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Hélène Eckert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Alexis Eschstruth

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jean-Baptiste Renaud

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Alena Shkumatava

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Lydia Teboul

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jim Kent

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jean-Stephane Joly

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

1 reference

5 July 2016

1 reference

12 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

1 reference

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10 June 2020

issue

1 reference

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10 June 2020

page(s)

148

1 reference

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describes a project that uses

10 June 2020

scikit-learn

object named as

scikit-learn

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

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1 reference

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Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq

2 October 2017

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Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.

2 October 2017

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PAM multiplicity marks genomic target sites as inhibitory to CRISPR-Cas9 editing

2 October 2017

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High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

2 October 2017

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2 October 2017

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Identification and characterization of essential genes in the human genome.

2 October 2017

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Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi

2 October 2017

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CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo

2 October 2017

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Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach

2 October 2017

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Sequence determinants of improved CRISPR sgRNA design

2 October 2017

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High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.

2 October 2017

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Cas9-chromatin binding information enables more accurate CRISPR off-target prediction.

2 October 2017

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CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool

2 October 2017

1 reference

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In vivo genome editing using Staphylococcus aureus Cas9

2 October 2017

1 reference

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CRISPR multitargeter: a web tool to find common and unique CRISPR single guide RNA targets in a set of similar sequences

2 October 2017

1 reference

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Dramatic enhancement of genome editing by CRISPR/Cas9 through improved guide RNA design

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

"Off-Spotter": very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Enhanced specificity and efficiency of the CRISPR/Cas9 system with optimized sgRNA parameters in Drosophila

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites.

2 October 2017

1 reference

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Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

CRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

2 October 2017

1 reference

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sgRNAcas9: a software package for designing CRISPR sgRNA and evaluating potential off-target cleavage sites

2 October 2017

1 reference

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Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

GT-Scan: identifying unique genomic targets

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Highly specific and efficient CRISPR/Cas9-catalyzed homology-directed repair in Drosophila

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Genetic screens in human cells using the CRISPR-Cas9 system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Genome engineering using the CRISPR-Cas9 system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

DNA targeting specificity of RNA-guided Cas9 nucleases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Efficient genome editing in zebrafish using a CRISPR-Cas system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Multiplex genome engineering using CRISPR/Cas systems

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Fast and accurate short read alignment with Burrows-Wheeler transform

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Rational siRNA design for RNA interference

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

The human genome browser at UCSC

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Sequence features associated with the cleavage efficiency of CRISPR/Cas9 system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Flexible guide-RNA design for CRISPR applications using Protospacer Workbench.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

Off-target mutations are rare in Cas9-modified mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

RNA events. Cas9 targeting and the CRISPR revolution

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

CRISPR-P: a web tool for synthetic single-guide RNA design of CRISPR-system in plants.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

E-CRISP: fast CRISPR target site identification

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

CasOT: a genome-wide Cas9/gRNA off-target searching tool

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934014

10.1186/S13059-016-1012-2

23 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

27380939

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27380939%20AND%20SRC:MED&resulttype=core&format=json