Characterization and Protective Activity of Monoclonal Antibodies Directed against Streptococcus suis Serotype 2 Capsular Polysaccharide Obtained Using a Glycoconjugate (Q89995322)

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scientific article published on 07 September 2019

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English	Characterization and Protective Activity of Monoclonal Antibodies Directed against Streptococcus suis Serotype 2 Capsular Polysaccharide Obtained Using a Glycoconjugate	scientific article published on 07 September 2019

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10 April 2020

Characterization and Protective Activity of Monoclonal Antibodies Directed against Streptococcus suis Serotype 2 Capsular Polysaccharide Obtained Using a Glycoconjugate (English)

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10 April 2020

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Streptococcus suis

object named as

Streptococcus suis

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Guillaume Goyette-Desjardins

1

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10 April 2020

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10 April 2020

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Sonia Lacouture

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10 April 2020

Jean-Philippe Auger

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10 April 2020

Marcelo Gottschalk

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10 April 2020

Mariela Segura

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10 April 2020

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7 September 2019

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10 April 2020

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10 April 2020

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10 April 2020

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Creative Commons Attribution 4.0 International

7 September 2019

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Continuous cultures of fused cells secreting antibody of predefined specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

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An update on Streptococcus suis identification

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

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based on heuristic

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Description of 14 new capsular types of Streptococcus suis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

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Antibody avidity determination by ELISA using thiocyanate elution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

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Mouse IgG antibodies have subclass associated affinity differences

1 reference

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based on heuristic

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Streptococcal infection in young pigs. V. An immunogenic polysaccharide from Streptococcus suis type 2 with particular reference to vaccination against streptococcal meningitis in pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of antibodies against Streptococcus suis capsular type 2 using a purified capsular polysaccharide antigen-based indirect ELISA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative preparation methods of sialylated capsule antigen from Streptococcus suis type 2 with type specific antigenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

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based on heuristic

inferred from PubMed ID database lookup

Characterization and protective activity of a monoclonal antibody against a capsular epitope shared by Streptococcus suis serotypes 1, 2 and 1/2

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

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Antibody avidity as a surrogate marker of successful priming by Haemophilus influenzae type b conjugate vaccines following infant immunization.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Avidity as a determinant of the protective efficacy of human antibodies to pneumococcal capsular polysaccharides

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

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Heat-killed Streptococcus suis capsular type 2 strains stimulate tumor necrosis factor alpha and interleukin-6 production by murine macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in functional antibody activity against Streptococcus pneumoniae in vaccinated elderly individuals highly correlates with decreased IgG antibody avidity

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG DNA induces stronger immune responses with less toxicity than other adjuvants

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Avidity, potency, and cross-reactivity of monoclonal antibodies to pneumococcal capsular polysaccharide serotype 6B

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

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Assessment of protective efficacy of live and killed vaccines based on a non-encapsulated mutant of Streptococcus suis serotype 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phagocytosis of microbes: complexity in action

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptococcus suis interactions with the murine macrophage cell line J774: adhesion and cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function relationships for human antibodies to pneumococcal capsular polysaccharide from transgenic mice with human immunoglobulin Loci

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The four mouse IgG isotypes differ extensively in bactericidal and opsonophagocytic activity when reacting with the P1.16 epitope on the outer membrane PorA protein of Neisseria meningitidis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LAMP proteins are required for fusion of lysosomes with phagosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptococcus suis serotype 2, an important swine and human pathogen, induces strong systemic and cerebral inflammatory responses in a mouse model of infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The multifunctional role of antibodies in the protective response to bacterial T cell-independent antigens.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vaccination of BALB/c mice with Escherichia coli-expressed vaccinia virus proteins A27L, B5R, and D8L protects mice from lethal vaccinia virus challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of opsonic and nonopsonic serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibodies against intranasal challenge with Streptococcus pneumoniae in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IgM in microbial infections: taken for granted?

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aggregation of Streptococcus pneumoniae by a pneumococcal capsular polysaccharide-specific human monoclonal IgM correlates with antibody efficacy in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptococcus suis: a new emerging or an old neglected zoonotic pathogen?

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure determination of Streptococcus suis serotype 2 capsular polysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement: a key system for immune surveillance and homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The efficacy of pneumococcal capsular polysaccharide-specific antibodies to serotype 3 Streptococcus pneumoniae requires macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organic Chemistry and Immunochemical Strategies in the Design of Potent Carbohydrate-based Vaccines

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minimization of bacterial size allows for complement evasion and is overcome by the agglutinating effect of antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibody requires Fcγ receptor III and macrophages to mediate protection against pneumococcal pneumonia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fisher scientific award lecture - the capsular polysaccharides of Group B Streptococcus and Streptococcus suis differently modulate bacterial interactions with dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sialylation of Streptococcus suis serotype 2 is essential for capsule expression but is not responsible for the main capsular epitope.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Future challenges in the elimination of bacterial meningitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fine specificity and cross-reactions of monoclonal antibodies to group B streptococcal capsular polysaccharide type III.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential idiotype utilization for the in vivo type 14 capsular polysaccharide-specific Ig responses to intact Streptococcus pneumoniae versus a pneumococcal conjugate vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of IgM and IgA antibody response to 23-valent pneumococcal polysaccharide vaccination in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of capsular polysaccharide synthesis gene clusters from all serotypes of Streptococcus suis: potential mechanisms for generation of capsular variation

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure determination of Streptococcus suis serotype 14 capsular polysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pneumococcal vaccine and opsonic pneumococcal antibody.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The function of Fcγ receptors in dendritic cells and macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody blocks acquisition of bacterial colonization through agglutination

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody response specific to the capsular polysaccharide is impaired in Streptococcus suis serotype 2-infected animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the capsular polysaccharide as a virulence factor for Streptococcus suis serotype 14

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptococcus suis, an important pig pathogen and emerging zoonotic agent-an update on the worldwide distribution based on serotyping and sequence typing

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of Complement in Antibody Therapy for Infectious Diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycans as Vaccine Antigens and Adjuvants: Immunological Considerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine Whole-Blood Opsonophagocytosis Assay to Evaluate Protection by Antibodies Raised Against Encapsulated Extracellular Bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptococcus suis vaccines: candidate antigens and progress

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IgM-Dependent Phagocytosis in Microglia Is Mediated by Complement Receptor 3, Not Fcα/μ Receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Symbol Nomenclature for Graphical Representations of Glycans

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Explaining the Serological Characteristics of Streptococcus suis Serotypes 1 and 1/2 from Their Capsular Polysaccharide Structure and Biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection against Streptococcus suis Serotype 2 Infection Using a Capsular Polysaccharide Glycoconjugate Vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Protective Value of Maternal Group B Streptococcus Antibodies: Quantitative and Functional Analysis of Naturally Acquired Responses to Capsular Polysaccharides and Pilus Proteins in European Maternal Sera

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure determination of Streptococcus suis serotype 9 capsular polysaccharide and assignment of functions of the cps locus genes involved in its biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determining Streptococcus suis serotype from short-read whole-genome sequencing data

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IgG subclass co-expression brings harmony to the quartet model of murine IgG function

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Porcine Dendritic Cells as an In Vitro Model to Assess the Immunological Behaviour of Streptococcus suis Subunit Vaccine Formulations and the Polarizing Effect of Adjuvants

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the Immunomodulatory Properties of Streptococcus suis and Group B Streptococcus Capsular Polysaccharides on the Humoral Response

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single amino acid polymorphism in the glycosyltransferase CpsK defines four Streptococcus suis serotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A capsular polysaccharide-specific antibody alters Streptococcus pneumoniae gene expression during nasopharyngeal colonization of mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptococcus suis serotype 3 and serotype 18 capsular polysaccharides contain di-N-acetyl-bacillosamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure determination of Streptococcus suis serotypes 7 and 8 capsular polysaccharides and assignment of functions of the cps locus genes involved in their biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31500262

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/PATHOGENS8030139

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Europe PubMed Central

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10 April 2020

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Europe PubMed Central

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10 April 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31500262%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

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