An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains (Q89683135)

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scientific article published on 10 February 2020

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English	An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains	scientific article published on 10 February 2020

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7 April 2020

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Europe PubMed Central

An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains (English)

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Europe PubMed Central

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7 April 2020

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Sara B Salazar

1

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7 April 2020

Rita S Simões

2

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7 April 2020

Nuno A Pedro

3

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7 April 2020

Maria Joana Pinheiro

4

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7 April 2020

Maria Fernanda N N Carvalho

5

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Europe PubMed Central

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7 April 2020

Nuno P Mira

6

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10 February 2020

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Europe PubMed Central

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7 April 2020

Journal of Fungi

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7 April 2020

6

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7 April 2020

1

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Europe PubMed Central

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7 April 2020

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Creative Commons Attribution 4.0 International

10 February 2020

1 reference

April 2022 Public Data File from Crossref

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0 references

Increase inCandida kruseiInfection among Patients with Bone Marrow Transplantation and Neutropenia Treated Prophylactically with Fluconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to polyene antibiotics and correlated sterol changes in two isolates of Candida tropicalis from a patient with an amphotericin B-resistant funguria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of resistance to 5-fluorocytosine in Candida parapsilosis during therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of fluconazole- and amphotericin B-resistant Candida albicans from blood of two patients with leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular biological characterization of an azole-resistant Candida glabrata isolate

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The G464S amino acid substitution in Candida albicans sterol 14alpha-demethylase causes fluconazole resistance in the clinic through reduced affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does long-term itraconazole prophylaxis result in in vitro azole resistance in mucosal Candida albicans isolates from persons with advanced human immunodeficiency virus infection? The National Institute of Allergy and Infectious Diseases Mycoses stu

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of ATP-binding-cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and expression of multidrug resistance-related ABC transporter genes in Candida krusei

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic Candida infection in University hospital 1997-1999: the distribution of Candida biotypes and antifungal susceptibility patterns

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antifungal agents: mechanisms of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guidelines for treatment of candidiasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of increased fluconazole resistance in Candida glabrata during prophylaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of azole resistance in petite mutants of Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clade-specific flucytosine resistance is due to a single nucleotide change in the FUR1 gene of Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-like transcription factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of primary resistance to flucytosine in Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antifungal susceptibilities of Candida species causing vulvovaginitis and epidemiology of recurrent cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of azole resistance in a clinical isolate of Candida tropicalis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of Candida albicans infections and role of non-Candida-albicans yeasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDR16-mediated azole resistance in Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tulbaghia alliacea phytotherapy: a potential anti-infective remedy for candidiasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aneuploidy and isochromosome formation in drug-resistant Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candida albicans and Candida glabrata clinical isolates exhibiting reduced echinocandin susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of candidemia in Brazil: a nationwide sentinel surveillance of candidemia in eleven medical centers

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Silver Colloid Nanoparticles: Synthesis, Characterization, and Their Antibacterial Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis, structure and biological activity of cobalt(II) and copper(II) complexes of valine-derived schiff bases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced susceptibility to polyenes associated with a missense mutation in the ERG6 gene in a clinical isolate of Candida glabrata with pseudohyphal growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vulvovaginal candidosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro antimicrobial properties of coconut oil on Candida species in Ibadan, Nigeria

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of DNA mismatch repair and double-strand break repair in genome stability and antifungal drug resistance in Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candida krusei, a multidrug-resistant opportunistic fungal pathogen: geographic and temporal trends from the ARTEMIS DISK Antifungal Surveillance Program, 2001 to 2005

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ATP-binding cassette transporter-encoding gene CgSNQ2 is contributing to the CgPDR1-dependent azole resistance of Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal population of flucytosine-resistant Candida tropicalis from blood cultures, Paris, France

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the multi-drug resistance regulator MRR1, followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antifungal activity and mode of action of silver nano-particles on Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug:H+ antiporters in chemical stress response in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the CgPDR1 and CgERG11 genes in azole-resistant Candida glabrata clinical isolates from Slovakia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of new chromosomes as a virulence mechanism in yeast Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candida colonisation as a source for candidaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antifungal activity of silver nanoparticles against Candida spp.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use?

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acquisition of flucytosine, azole, and caspofungin resistance in Candida glabrata bloodstream isolates serially obtained from a hematopoietic stem cell transplant recipient.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel FKS mutations associated with echinocandin resistance in Candida species

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: a 10.5-year analysis of susceptibilities of Candida Species to fluconazole and voriconazole as determined by CLSI standardized disk diffusion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between antifungal resistance of fluconazole resistant Candida albicans and mutations in ERG11 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lactic acid bacteria colonization and clinical outcome after probiotic supplementation in conventionally treated bacterial vaginosis and vulvovaginal candidiasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14alpha-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microarray and molecular analyses of the azole resistance mechanism in Candida glabrata oropharyngeal isolates

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

National surveillance of fungemia in Denmark (2004 to 2009)

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type MIC distributions, epidemiological cutoff values and species-specific clinical breakpoints for fluconazole and Candida: Time for harmonization of CLSI and EUCAST broth microdilution methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An A643V amino acid substitution in Upc2p contributes to azole resistance in well-characterized clinical isolates of Candida albicans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type MIC distributions and epidemiological cutoff values for posaconazole and voriconazole and Candida spp. as determined by 24-hour CLSI broth microdilution

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of Heterozygosity of FCY2 Leading to the Development of Flucytosine Resistance in Candida tropicalis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional profiling of azole-resistant Candida parapsilosis strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Silver colloidal nanoparticles: antifungal effect against adhered cells and biofilms of Candida albicans and Candida glabrata.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The microbiota of the vagina and its influence on women's health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azole resistance by loss of function of the sterol Δ⁵,⁶-desaturase gene (ERG3) in Candida albicans does not necessarily decrease virulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candida spp. with acquired echinocandin resistance, France, 2004-2010.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type MIC distributions and epidemiological cutoff values for amphotericin B, flucytosine, and itraconazole and Candida spp. as determined by CLSI broth microdilution

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Facultative sterol uptake in an ergosterol-deficient clinical isolate of Candida glabrata harboring a missense mutation in ERG11 and exhibiting cross-resistance to azoles and amphotericin B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding vaginal microbiome complexity from an ecological perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Species identification and antifungal susceptibility testing of Candida bloodstream isolates from population-based surveillance studies in two U.S. cities from 2008 to 2011.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two clinical isolates of Candida glabrata exhibiting reduced sensitivity to amphotericin B both harbor mutations in ERG2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STB5 is a negative regulator of azole resistance in Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hidden killers: human fungal infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erg11 mutations associated with azole resistance in clinical isolates of Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiological changes with potential implication for antifungal prescription recommendations for fungaemia: data from a nationwide fungaemia surveillance programme.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candida glabrata drug:H+ antiporter CgQdr2 confers imidazole drug resistance, being activated by transcription factor CgPdr1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversion of a fungal genetic code alteration links proteome instability with genomic and phenotypic diversification

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dual role of candida glabrata drug:H+ antiporter CgAqr1 (ORF CAGL0J09944g) in antifungal drug and acetic acid resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of eating probiotic yogurt on colonization by Candida species of the oral and vaginal mucosa in HIV-infected and HIV-uninfected women

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of the CgPDR16 gene attenuates azole tolerance and biofilm production in pathogenic Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deciphering azole resistance mechanisms with a focus on transcription factor-encoding genes TAC1, MRR1 and UPC2 in a set of fluconazole-resistant clinical isolates of Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced susceptibility of Candida albicans clinical isolates to azoles and detection of mutations in the ERG11 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct roles of Candida albicans drug resistance transcription factors TAC1, MRR1, and UPC2 in virulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between copy number and expression level of genes involved in fluconazole resistance in Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candida glabrata drug:H+ antiporter CgTpo3 (ORF CAGL0I10384g): role in azole drug resistance and polyamine homeostasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UPC2A is required for high-level azole antifungal resistance in Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and optimization of highly-selective fungal CYP51 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of echinocandins and triazoles against a contemporary (2012) worldwide collection of yeast and moulds collected from invasive infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of clinically derived mutations in ERG11 to azole resistance in Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of fluconazole resistance in Candida parapsilosis isolates from a U.S. surveillance system

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current methods for identifying clinically important cryptic Candida species

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azole antifungals: 35 years of invasive fungal infection management

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antifungal activity of clotrimazole against Candida albicans depends on carbon sources, growth phase and morphology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of Vaginal Lactobacilli and Characterization of Anti-Candida Activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug Transporters and Alterations in Sterol Biosynthesis Contribute to Azole Antifungal Resistance in Candida parapsilosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of fluconazole resistance in a series of Candida parapsilosis isolates from a persistent candidemia patient with prolonged antifungal therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of silver nanoparticles: chemical, physical and biological methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane Proteome-Wide Response to the Antifungal Drug Clotrimazole in Candida glabrata: Role of the Transcription Factor CgPdr1 and the Drug:H+ Antiporters CgTpo1_1 and CgTpo1_2

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of mutations in transcription factors of efflux pump genes in fluconazole-resistant Candida albicans strains overexpressing the efflux pumps

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel bio-essential metal based complexes linked by heterocyclic ligand: Synthesis, structural elucidation, biological investigation and docking analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical Appearance of Oral Candida Infection and Therapeutic Strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Executive Summary: Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Probiotics as Antifungals in Mucosal Candidiasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The putative ABC transporter encoded by the orf19.4531 plays a role in the sensitivity of Candida albicans cells to azole antifungal drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Water-soluble and photo-stable silver(I) dicarboxylate complexes containing 1,10-phenanthroline ligands: Antimicrobial and anticancer chemotherapeutic potential, DNA interactions and antioxidant activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance Mechanisms and Clinical Features of Fluconazole-Nonsusceptible Candida tropicalis Isolates Compared with Fluconazole-Less-Susceptible Isolates

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antifungal Susceptibility Analysis of Clinical Isolates of Candida parapsilosis in Iran

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clotrimazole Drug Resistance in Candida glabrata Clinical Isolates Correlates with Increased Expression of the Drug:H(+) Antiporters CgAqr1, CgTpo1_1, CgTpo3, and CgQdr2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Species Distribution and In Vitro Antifungal Susceptibility of Vulvovaginal Candida Isolates in China

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of UPC2 Gene in Azole-Resistant Candida tropicalis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERG11 mutations and upregulation in clinical itraconazole-resistant isolates of Candida krusei

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The PathoYeastract database: an information system for the analysis of gene and genomic transcription regulation in pathogenic yeasts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial metal-based thiophene derived compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In Vitro Activities of Novel Azole Compounds ATTAF-1 and ATTAF-2 against Fluconazole-Susceptible and -Resistant Isolates of Candida Species.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional Control of Drug Resistance, Virulence and Immune System Evasion in Pathogenic Fungi: A Cross-Species Comparison

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety and Pharmacokinetics of CD101 IV, a Novel Echinocandin, in Healthy Adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations and/or Overexpressions of ERG4 and ERG11 Genes in Clinical Azoles-Resistant Isolates of Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of a Long-Acting Echinocandin (CD101) and Seven Comparator Antifungal Agents Tested against a Global Collection of Contemporary Invasive Fungal Isolates in the SENTRY 2014 Antifungal Surveillance Program

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluconazole and Echinocandin Resistance of Candida glabrata Correlates Better with Antifungal Drug Exposure Rather than with MSH2 Mutator Genotype in a French Cohort of Patients Harboring Low Rates of Resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design, synthesis and spectroscopic characterization of metal (II) complexes derived from a tetradentate macrocyclic ligand: Study on antimicrobial and antioxidant capacity of complexes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of Antibacterial and Technological Properties of Vaginal Lactobacilli for Their Potential Application in Dairy Products.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel alkylated azoles as potent antifungals

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive Fitness of Fluconazole-Resistant Clinical Candida albicans Strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ag(I) camphorimine complexes with antimicrobial activity towards clinically important bacteria and species of the Candida genus

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antifungal Activity of the Biphosphinic Cyclopalladate C7a against Candida albicans Yeast Forms In Vitro and In Vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD101, a long-acting echinocandin, and comparator antifungal agents tested against a global collection of invasive fungal isolates in the SENTRY 2015 Antifungal Surveillance Program

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adaptive Mistranslation Accelerates the Evolution of Fluconazole Resistance and Induces Major Genomic and Gene Expression Alterations in Candida albicans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Virulence factors, antifungal susceptibility and molecular mechanisms of azole resistance among Candida parapsilosis complex isolates recovered from clinical specimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative genomic and transcriptomic analyses unveil novel features of azole resistance and adaptation to the human host in Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New Horizons in Antifungal Therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Research of Mrr1, Cap1 and MDR1 in Candida albicans resistant to azole medications

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rezafungin (CD101), a next generation echinocandin. A systematic literature review and assessment of possible place in therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Profiling of PDR1 and MSH2 in Candida glabrata Bloodstream Isolates from a Multi-Center Study in China.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Worldwide emergence of resistance to antifungal drugs challenges human health and food security

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Host-Pathogen Interactions Mediated by MDR Transporters in Fungi: As Pleiotropic as it Gets!

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mononuclear silver(I) complexes with 1,7-phenanthroline as potent inhibitors of Candida growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multilocus Sequence Typing (MLST) Genotypes of Bloodstream Isolates in Korea: Association With Antifungal Resistance, Mutations in Mismatch Repair Gene (Msh2), and Clinical Outcomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antifungal Activity and Mechanism of Action of the Co(III) Coordination Complexes With Diamine Chelate Ligands Against Reference and Clinical Strains of Candida spp

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of fluconazole prophylaxis on Candida fluconazole susceptibility in premature infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Acetic Acid and Lactic Acid at Low pH in Growth and Azole Resistance of Candida albicans and Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of lipid transporters in fungal physiology and pathogenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/32050673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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