fMLP-dependent activation of Akt and ERK1/2 through ROS/Rho A pathways is mediated through restricted activation of the FPRL1 (FPR2) receptor (Q89160586)

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scientific article published on 19 June 2018

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English	fMLP-dependent activation of Akt and ERK1/2 through ROS/Rho A pathways is mediated through restricted activation of the FPRL1 (FPR2) receptor	scientific article published on 19 June 2018

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29922854%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

fMLP-dependent activation of Akt and ERK1/2 through ROS/Rho A pathways is mediated through restricted activation of the FPRL1 (FPR2) receptor (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29922854%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Wissam H. Faour

1

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1 April 2020

author name string

Hussein Fayyad-Kazan

2

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1 April 2020

Nabil El Zein

3

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1 April 2020

publication date

19 June 2018

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1 April 2020

Inflammation Research

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1 April 2020

67

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1 April 2020

8

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1 April 2020

711-722

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PubMed publication ID

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1 April 2020

A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and myosin phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoattractant signaling and leukocyte activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of endothelial cell gap formation and barrier dysfunction: role of myosin light chain phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of myosin light-chain phosphorylation in endothelial cell retraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A peptide with unique receptor specificity: stimulation of phosphoinositide hydrolysis and induction of superoxide generation in human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T21/DP107, A synthetic leucine zipper-like domain of the HIV-1 envelope gp41, attracts and activates human phagocytes by using G-protein-coupled formyl peptide receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic peptide derived from human immunodeficiency virus type 1 gp120 downregulates the expression and function of chemokine receptors CCR5 and CXCR4 in monocytes by activating the 7-transmembrane G-protein-coupled receptor FPRL1/LXA4R.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

fMet-Leu-Phe Stimulates Proinflammatory Cytokine Gene Expression in Human Peripheral Blood Monocytes: The Role of Phosphatidylinositol 3-Kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synthetic chemoattractant Trp-Lys-Tyr-Met-Val-DMet activates neutrophils preferentially through the lipoxin A(4) receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The epidemiology of the systemic inflammatory response

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the chemotactic peptide receptor FPRL1 in monocytes phosphorylates the chemokine receptor CCR5 and attenuates cell responses to selected chemokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurotoxic prion peptide fragment PrP(106-126) is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synthetic peptide WKYMVm attenuates the function of the chemokine receptors CCR5 and CXCR4 through activation of formyl peptide receptor-like 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formyl-peptide receptors revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoxin A4 stimulates a cytosolic Ca2+ increase in human bronchial epithelium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel strategies for the treatment of sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of human polymorphonuclear leukocytes functions by the neuropeptide pituitary adenylate cyclase-activating polypeptide after activation of MAPKs

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel protein kinase C (PKCepsilon) is required for fMet-Leu-Phe-induced activation of NF-kappaB in human peripheral blood monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction pathways triggered by selective formylpeptide analogues in human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of novel formyl peptide receptor-like 1 agonists that induce macrophage tumor necrosis factor alpha production.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formyl-peptide receptor like 1: a potent mediator of the Ca2+ release-activated Ca2+ current ICRAC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The actin cytoskeleton in endothelial cell phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidylglycerol inhibits formyl peptide receptorlike-1-stimulated chemotactic migration and IL-1beta production from human phagocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF receptor activation by GPCRs: an universal pathway reveals different versions

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crosstalks between the receptors tyrosine kinase EGFR and TrkA and the GPCR, FPR, in human monocytes are essential for receptors-mediated cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase A phosphorylation of tau-serine 214 reorganizes microtubules and disrupts the endothelial cell barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Humanins, the neuroprotective and cytoprotective peptides with antiapoptotic and anti-inflammatory properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho GTPases and their role in organizing the actin cytoskeleton.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pathology of the shock syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil recruitment and function in health and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum amyloid A stimulates lipoprotein-associated phospholipase A2 expression in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The complexity of NF-κB signaling in inflammation and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor activates the Rho GTPase-activating protein (GAP) Deleted in Liver Cancer 1 via focal adhesion kinase and protein phosphatase 2A

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoxin A4 mediates aortic contraction via RHOA/RHO kinase, endothelial dysfunction and reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood cells and endothelial barrier function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the Rho/Rho kinase pathway prevents lipopolysaccharide-induced hyperalgesia and the release of TNF-α and IL-1β in the mouse spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T Lymphocyte-Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific Immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sepsis-induced myocardial dysfunction: pathophysiology and management

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monocyte-mediated defense against bacteria, fungi, and parasites

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of sepsis-induced myocardial dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho GTPases and actomyosin: Partners in regulating epithelial cell-cell junction structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/29922854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00011-018-1163-6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29922854%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29922854%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

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