CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase (Q73066505)

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scientific article published on 01 October 2000

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English	CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase	scientific article published on 01 October 2000

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instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

title

CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase (English)

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

main subject

microglia

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based on heuristic

inferred from title

author name string

J Tan

series ordinal

1

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

T Town

series ordinal

2

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

T Mori

series ordinal

3

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

Y Wu

series ordinal

4

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

M Saxe

series ordinal

5

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

F Crawford

series ordinal

6

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

M Mullan

series ordinal

7

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

publication date

1 October 2000

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Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

published in

Journal of Neuroscience

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stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

volume

20

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Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

issue

20

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

page(s)

7587-7594

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

cites work

Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

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Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

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Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-alpha production that is opposed by TGF-beta 1 and IL-10

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

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Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

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CD40-mediated signal transduction in human airway smooth muscle

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of protein tyrosine kinases and phosphatases in isotype switching: crosslinking CD45 to CD40 inhibits IgE isotype switching in human B cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

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Nonsteroidal anti-inflammatory drugs in Alzheimer's disease.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

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Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

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Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 activation boosts T cell immunity in vivo by enhancing T cell clonal expansion and delaying peripheral T cell deletion

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune system-associated antigens on the surface of peripheral blood lymphocytes in patients with Alzheimer's disease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased levels of alpha-1-antichymotrypsin in brains of patients with Alzheimer's disease correlate with activated astrocytes and are affected by APOE 4 genotype

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

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Inflammation and Alzheimer's disease pathogenesis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

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Neurotrophin signaling via Trks and p75.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonsteroidal anti-inflammatory drug use and Alzheimer's disease: a case-control study in Rochester, Minnesota, 1980 through 1984.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatase activity toward abnormally phosphorylated tau: decrease in Alzheimer disease brain.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoreactivity of CD45, a protein phosphotyrosine phosphatase, in Alzheimer's disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial tyrosine phosphorylation systems in normal and degenerating brain

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of CD45 in Signal Transduction

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular distribution of protein phosphatases and abnormally phosphorylated tau in the temporal cortex from Alzheimer's disease and control brains

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 signaling of monocyte inflammatory cytokine synthesis through an ERK1/2-dependent pathway. A target of interleukin (il)-4 and il-10 anti-inflammatory action

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated microglia mediate neuronal cell injury via a nitric oxide mechanism

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11027218

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1523/JNEUROSCI.20-20-07587.2000

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

PMC publication ID

6772874

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

PubMed publication ID

11027218

1 reference

stated in

Europe PubMed Central

PMC publication ID

6772874

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11027218%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 October 2019

 

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