The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70 (Q77879011)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10367886%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70 (English)

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8 December 2019

C Voisine

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8 December 2019

E A Craig

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8 December 2019

N Zufall

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8 December 2019

O von Ahsen

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8 December 2019

N Pfanner

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8 December 2019

W Voos

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8 December 2019

language of work or name

English

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publication date

1 May 1999

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8 December 2019

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8 December 2019

volume

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8 December 2019

issue

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8 December 2019

page(s)

565-574

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Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane

8 December 2019

cites work

1 reference

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7 January 2021

Separation of structural and dynamic functions of the mitochondrial translocase: Tim44 is crucial for the inner membrane import sites in translocation of tightly folded domains, but not of loosely folded preproteins

1 reference

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7 January 2021

Strong precursor-pore interactions constrain models for mitochondrial protein import

1 reference

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7 January 2021

The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44.

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7 January 2021

Biogenesis of the gram-negative bacterial envelope

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7 January 2021

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria.

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7 January 2021

A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins

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7 January 2021

The sorting signal of cytochrome b2 promotes early divergence from the general mitochondrial import pathway and restricts the unfoldase activity of matrix Hsp70.

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7 January 2021

Unfolding of preproteins upon import into mitochondria

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7 January 2021

Can Hsp70 proteins act as force-generating motors?

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7 January 2021

Import of cytochrome b2 to the mitochondrial intermembrane space: the tightly folded heme-binding domain makes import dependent upon matrix ATP.

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7 January 2021

BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation

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7 January 2021

The mitochondrial protein import motor: dissociation of mitochondrial hsp70 from its membrane anchor requires ATP binding rather than ATP hydrolysis

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7 January 2021

Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins

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7 January 2021

Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane

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7 January 2021

Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP.

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7 January 2021

Active unfolding of precursor proteins during mitochondrial protein import

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7 January 2021

Protein import into mitochondria

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7 January 2021

Gene conversion adjacent to regions of double-strand break repair

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7 January 2021

Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis

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7 January 2021

Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p

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7 January 2021

ProMod and Swiss-Model: Internet-based tools for automated comparative protein modelling

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7 January 2021

Protein sorting. Pulling in the proteins

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7 January 2021

Mitochondrial preprotein translocase

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7 January 2021

Polypeptides traverse the mitochondrial envelope in an extended state

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7 January 2021

Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44

1 reference

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7 January 2021

Protein translocation across mitochondrial membranes: What a long, strange trip it is

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7 January 2021

Common principles of protein translocation across membranes

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7 January 2021

Mitochondrial Hsp70/MIM44 complex facilitates protein import

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7 January 2021

Targeting of cytochrome b2 into the mitochondrial intermembrane space: specific recognition of the sorting signal.

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7 January 2021

What drives the translocation of proteins?

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7 January 2021

Analysis of mitochondrial protein import using translocation intermediates and specific antibodies.

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7 January 2021

The requirement of matrix ATP for the import of precursor proteins into the mitochondrial matrix and intermembrane space.

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7 January 2021

The role of Hsp70 in conferring unidirectionality on protein translocation into mitochondria

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7 January 2021

The mitochondrial protein import machinery. Role of ATP in dissociation of the Hsp70.Mim44 complex

1 reference

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7 January 2021

Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix

1 reference

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7 January 2021

Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins.

1 reference

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7 January 2021

Structural analysis of substrate binding by the molecular chaperone DnaK

1 reference

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7 January 2021

10.1016/S0092-8674(00)80768-0

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10367886%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

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