Separation of structural and dynamic functions of the mitochondrial translocase: Tim44 is crucial for the inner membrane import sites in translocation of tightly folded domains, but not of loosely folded preproteins (Q41950610)

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scientific article published on August 1998

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English	Separation of structural and dynamic functions of the mitochondrial translocase: Tim44 is crucial for the inner membrane import sites in translocation of tightly folded domains, but not of loosely folded preproteins	scientific article published on August 1998

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Separation of structural and dynamic functions of the mitochondrial translocase: Tim44 is crucial for the inner membrane import sites in translocation of tightly folded domains, but not of loosely folded preproteins (English)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

author name string

Bömer U

1

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Europe PubMed Central

PMC publication ID

14 October 2017

Maarse AC

2

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Europe PubMed Central

PMC publication ID

14 October 2017

Martin F

3

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Geissler A

4

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Merlin A

5

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Schönfisch B

6

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Meijer M

7

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Pfanner N

8

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Europe PubMed Central

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14 October 2017

Rassow J

9

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PMC publication ID

14 October 2017

language of work or name

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publication date

1 August 1998

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Europe PubMed Central

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14 October 2017

The EMBO Journal

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Europe PubMed Central

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14 October 2017

17

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Europe PubMed Central

PMC publication ID

14 October 2017

15

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

4226-4237

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Biogenesis of Tim23 and Tim17, integral components of the TIM machinery for matrix-targeted preproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Carrier protein import into mitochondria mediated by the intermembrane proteins Tim10/Mrs11 and Tim12/Mrs5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Import of mitochondrial carriers mediated by essential proteins of the intermembrane space

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Characterization of mammalian translocase of inner mitochondrial membrane (Tim44) isolated from diabetic newborn mouse kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Characterization of the mitochondrial inner membrane translocase complex: the Tim23p hydrophobic domain interacts with Tim17p but not with other Tim23p molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Active unfolding of precursor proteins during mitochondrial protein import

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Protein import into mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Tom5 functionally links mitochondrial preprotein receptors to the general import pore.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

The lumenal domain of Sec63p stimulates the ATPase activity of BiP and mediates BiP recruitment to the translocon in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Tim23, a protein import component of the mitochondrial inner membrane, is required for normal activity of the multiple conductance channel, MCC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Probing the environment along the protein import pathways in yeast mitochondria by site-specific photocrosslinking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

The protein import system of mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Characterization of the preprotein translocase of the outer mitochondrial membrane by blue native electrophoresis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Role of Tim23 as voltage sensor and presequence receptor in protein import into mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Uniform nomenclature for the protein transport machinery of the mitochondrial membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

The mitochondrial protein import motor: dissociation of mitochondrial hsp70 from its membrane anchor requires ATP binding rather than ATP hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

The delta psi- and Hsp70/MIM44-dependent reaction cycle driving early steps of protein import into mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Mitochondrial GrpE modulates the function of matrix Hsp70 in translocation and maturation of preproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Targeting of cytochrome b2 into the mitochondrial intermembrane space: specific recognition of the sorting signal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

The signal that sorts yeast cytochrome b2 to the mitochondrial intermembrane space contains three distinct functional regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

MAS6 encodes an essential inner membrane component of the yeast mitochondrial protein import pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Protein import into yeast mitochondria: the inner membrane import site protein ISP45 is the MPI1 gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Import of cytochrome b2 to the mitochondrial intermembrane space: the tightly folded heme-binding domain makes import dependent upon matrix ATP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

The essential yeast protein MIM44 (encoded by MPI1) is involved in an early step of preprotein translocation across the mitochondrial inner membrane.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Identification of the essential yeast protein MIM17, an integral mitochondrial inner membrane protein involved in protein import

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Mitochondrial Hsp70/MIM44 complex facilitates protein import

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Mitochondrial GrpE is present in a complex with hsp70 and preproteins in transit across membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

SMS1, a high-copy suppressor of the yeast mas6 mutant, encodes an essential inner membrane protein required for mitochondrial protein import

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Molecular chaperones and intracellular protein translocation

1 reference

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5 June 2018

Can Hsp70 proteins act as force-generating motors?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Dynamic interaction of the protein translocation systems in the inner and outer membranes of yeast mitochondria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Protein sorting. Pulling in the proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

The MIM complex mediates preprotein translocationacross the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP driving system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Protein translocation across mitochondrial membranes: What a long, strange trip it is

1 reference

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The imported preprotein of the proteolipid subunit of the mitochondrial ATP synthase from Neurospora crassa. Molecular cloning and sequencing of the mRNA

1 reference

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5 June 2018

Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

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Studies on the mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles.

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5 June 2018

Structure, expression and regulation of a nuclear gene encoding a mitochondrial protein: the yeast L(+)-lactate cytochrome c oxidoreductase (cytochrome b2)

1 reference

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5 June 2018

A chimeric mitochondrial precursor protein with internal disulfide bridges blocks import of authentic precursors into mitochondria and allows quantitation of import sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Translocation arrest by reversible folding of a precursor protein imported into mitochondria. A means to quantitate translocation contact sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

A precursor protein partly translocated into yeast mitochondria is bound to a 70 kd mitochondrial stress protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Role of an energized inner membrane in mitochondrial protein import. Delta psi drives the movement of presequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Identification of a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

MPI1, an essential gene encoding a mitochondrial membrane protein, is possibly involved in protein import into yeast mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

5 June 2018

Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

18 August 2018

Identification of MIM23, a putative component of the protein import machinery of the mitochondrial inner membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

18 August 2018

The requirement of matrix ATP for the import of precursor proteins into the mitochondrial matrix and intermembrane space.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170756

18 August 2018

Polypeptides traverse the mitochondrial envelope in an extended state

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The polytopic mitochondrial inner membrane proteins MIM17 and MIM23 operate at the same preprotein import site

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial protein import machinery. Role of ATP in dissociation of the Hsp70.Mim44 complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial protein import: nucleoside triphosphates are involved in conferring import-competence to precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Energy requirements for unfolding and membrane translocation of precursor proteins during import into mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Just follow the acid chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional and physical interactions of components of the yeast mitochondrial inner-membrane import machinery (MIM)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mas6p can be cross-linked to an arrested precursor and interacts with other proteins during mitochondrial protein import

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of Hsp70 in conferring unidirectionality on protein translocation into mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein import into the yeast mitochondrial matrix. A new translocation intermediate between the two mitochondrial membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partner proteins determine multiple functions of Hsp70

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial import of subunit Va of cytochrome c oxidase characterized with yeast mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/9687491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EMBOJ/17.15.4226

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

ResearchGate publication ID

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