Structural insights into the function of type IB topoisomerases (Q74520769)

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11 November 2019

title

Structural insights into the function of type IB topoisomerases (English)

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11 November 2019

M R Redinbo

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11 November 2019

J J Champoux

series ordinal

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11 November 2019

W G Hol

series ordinal

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11 November 2019

publication date

1 February 1999

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Current Opinion in Structural Biology

11 November 2019

published in

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11 November 2019

volume

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11 November 2019

issue

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11 November 2019

page(s)

29-36

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11 November 2019

1 reference

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Domains of human topoisomerase I and associated functions.

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Eukaryotic DNA topoisomerases I.

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Mammalian DNA topoisomerase IIIalpha is essential in early embryogenesis

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Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I

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A 26 kDa yeast DNA topoisomerase I fragment: crystallographic structure and mechanistic implications

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Crystal structure of the amino-terminal fragment of vaccinia virus DNA topoisomerase I at 1.6 A resolution

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Solution structure of the C-terminal single-stranded DNA-binding domain of Escherichia coli topoisomerase I

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Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

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A model for the mechanism of human topoisomerase I

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Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases

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The domain organization of human topoisomerase I

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Biochemical and biophysical analyses of recombinant forms of human topoisomerase I

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Identification of a nucleolin binding site in human topoisomerase I

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Simian virus 40 large T antigen binds to topoisomerase I.

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7 January 2021

Mammalian DNA topoisomerase I activity and poisoning by camptothecin are inhibited by simian virus 40 large T antigen

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7 January 2021

Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

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DNA topoisomerase I is involved in both repression and activation of transcription

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7 January 2021

Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription

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7 January 2021

Reconstitution of human topoisomerase I by fragment complementation

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7 January 2021

Flexibility in DNA recombination: structure of the lambda integrase catalytic core

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7 January 2021

Crystal structure of the site-specific recombinase, XerD.

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7 January 2021

Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA

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7 January 2021

Topoisomerase I has a strong binding preference for a conserved hexadecameric sequence in the promoter region of the rRNA gene from Tetrahymena pyriformis

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Mutational analysis of vaccinia virus topoisomerase identifies residues involved in DNA binding

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Structure and mechanism of DNA topoisomerase II

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Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse

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Conserved themes but novel activities in recombinases and topoisomerases

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Teaching a new dog old tricks?

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Molecular organization in site-specific recombination: the catalytic domain of bacteriophage HP1 integrase at 2.7 A resolution

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Recent advances in the discovery and development of topoisomerase inhibitors as antitumor agents

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CPT-11 (Irinotecan) in the treatment of colorectal cancer

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The clinical status of irinotecan (CPT-11), a novel water soluble camptothecin analogue: 1996.

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Current perspectives on camptothecins in cancer treatment

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Phase I and pharmacology study of intoplicine (RP 60475; NSC 645008), novel topoisomerase I and II inhibitor, in cancer patients

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Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin

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Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites

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Identifiers

DOI

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11 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10047584%20AND%20SRC:MED&resulttype=core&format=json