DNA topoisomerase I is involved in both repression and activation of transcription (Q42508509)

1 November 2017

title

DNA topoisomerase I is involved in both repression and activation of transcription (English)

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1 November 2017

Merino A

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1 November 2017

Madden KR

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1 November 2017

Lane WS

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1 November 2017

Champoux JJ

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1 November 2017

Reinberg D

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1 November 2017

language of work or name

English

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publication date

1 September 1993

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1 November 2017

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1 November 2017

volume

365

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1 November 2017

issue

6443

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1 November 2017

page(s)

227-232

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1 November 2017

cites work

Activators and targets

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7 January 2021

Binding of general transcription factor TFIIB to an acidic activating region

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7 January 2021

Reduced binding of TFIID to transcriptionally compromised mutants of VP16.

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7 January 2021

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

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7 January 2021

GAL4 derivatives function alone and synergistically with mammalian activators in vitro

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7 January 2021

cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment

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7 January 2021

Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei

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7 January 2021

Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.

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7 January 2021

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7 January 2021

Transcription by RNA polymerase II: initiator-directed formation of transcription-competent complexes

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7 January 2021

Factors involved in specific transcription by mammalian RNA polymerase II: purification and analysis of transcription factor IIA and identification of transcription factor IIJ.

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7 January 2021

Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter

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7 January 2021

Five intermediate complexes in transcription initiation by RNA polymerase II

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7 January 2021

Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex

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7 January 2021

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains

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7 January 2021

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

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7 January 2021

Commitment and activation at pol II promoters: a tail of protein-protein interactions

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7 January 2021

Eukaryotic coactivators associated with the TATA box binding protein

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7 January 2021

Wild-type p53 binds to the TATA-binding protein and represses transcription

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7 January 2021

Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53.

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7 January 2021

A general topoisomerase I-dependent transcriptional repression in the stationary phase in yeast

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7 January 2021

Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome

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7 January 2021

Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities

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7 January 2021

Supercoiling of the DNA template during transcription

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7 January 2021

Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene

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7 January 2021

Cloning of yeast TOP1, the gene encoding DNA topoisomerase I, and construction of mutants defective in both DNA topoisomerase I and DNA topoisomerase II.

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7 January 2021

DNA topoisomerase I is essential in Drosophila melanogaster

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7 January 2021

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

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7 January 2021

Family of proteins that interact with TFIID and regulate promoter activity

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7 January 2021

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

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7 January 2021

Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II

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7 January 2021

Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes

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7 January 2021

Sequence-specific antirepression of histone H1-mediated inhibition of basal RNA polymerase II transcription

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7 January 2021

Mechanism of transcriptional antirepression by GAL4-VP16

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7 January 2021

The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex

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7 January 2021

Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro

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7 January 2021

Transcription activation by the adenovirus E1a protein

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7 January 2021

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex

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7 January 2021

Cloning of a human gene encoding the general transcription initiation factor IIB

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7 January 2021

Escherichia coli DNA topoisomerase III: purification and characterization of a new type I enzyme

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7 January 2021

A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein

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7 January 2021

Mechanism of transcriptional activation by Sp1: evidence for coactivators

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7 January 2021

Identifiers

DOI

10.1038/365227A0

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Dimensions Publication ID

1 November 2017

1033999819

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