Tumour necrosis factor and cancer (Q61819217)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

review article

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title

Tumour necrosis factor and cancer (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

0 references

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Frances Balkwill

series ordinal

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language of work or name

English

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publication date

3 April 2009

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

published in

Nature Reviews Cancer

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25 January 2020

volume

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25 January 2020

issue

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25 January 2020

page(s)

361-371

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An endotoxin-induced serum factor that causes necrosis of tumors

25 January 2020

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Tumor necrosis factor antagonist mechanisms of action: a comprehensive review

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A phase II study of etanercept (Enbrel), a tumor necrosis factor alpha inhibitor in patients with metastatic breast cancer.

31 March 2020

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Study of etanercept, a tumor necrosis factor-alpha inhibitor, in recurrent ovarian cancer

31 March 2020

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Tumor Necrosis Factor α As a New Target for Renal Cell Carcinoma: Two Sequential Phase II Trials of Infliximab at Standard and High Dose

31 March 2020

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A clinical study assessing the tolerability and biological effects of infliximab, a TNF-α inhibitor, in patients with advanced cancer

31 March 2020

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Tumor necrosis factor: renaissance as a cancer therapeutic?

31 March 2020

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II. Contribution to the Knowledge of Sarcoma

31 March 2020

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Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon

31 March 2020

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Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

31 March 2020

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Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

31 March 2020

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Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor

31 March 2020

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Molecular cloning of mouse tumour necrosis factor cDNA and its eukaryotic expression

31 March 2020

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Use of monoclonal antibodies to a human cytotoxin for its isolation and for examining the self-induction of resistance to this protein

31 March 2020

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The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games

31 March 2020

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An APRIL to remember: novel TNF ligands as therapeutic targets

31 March 2020

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TNF family ligands define niches for T cell memory.

31 March 2020

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Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

31 March 2020

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Molecular cloning and expression of a receptor for human tumor necrosis factor

31 March 2020

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A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins

31 March 2020

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Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor

31 March 2020

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Many cytokines are very useful therapeutic targets in disease

31 March 2020

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Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis

31 March 2020

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In vivo anti-tumour activity of recombinant human and murine TNF, alone and in combination with murine IFN-gamma, on a syngeneic murine melanoma.

31 March 2020

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Tumor necrosis factor/cachectin-induced intravascular fibrin formation in meth A fibrosarcomas

31 March 2020

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Cytokines as communication signals between leukocytes and endothelial cells

31 March 2020

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The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors

31 March 2020

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The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity

31 March 2020

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High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma

31 March 2020

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Synergistic effects of TNF-alpha and melphalan in an isolated limb perfusion model of rat sarcoma: a histopathological, immunohistochemical and electron microscopical study

31 March 2020

1 reference

TNF-alpha augments intratumoural concentrations of doxorubicin in TNF-alpha-based isolated limb perfusion in rat sarcoma models and enhances anti-tumour effects

31 March 2020

1 reference

Tumor necrosis factor alpha mediates homogeneous distribution of liposomes in murine melanoma that contributes to a better tumor response

31 March 2020

1 reference

Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.

31 March 2020

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The effect of recombinant human tumour necrosis factor on growth and macromolecular synthesis of human epithelial cells

31 March 2020

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Recombinant tumor necrosis factor: its effect and its synergism with interferon-gamma on a variety of normal and transformed human cell lines

31 March 2020

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Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon

31 March 2020

1 reference

Crucial role of TNF-alpha in CD8 T cell-mediated elimination of 3LL-A9 Lewis lung carcinoma cells in vivo.

31 March 2020

1 reference

Compromised anti-tumor responses in tumor necrosis factor-alpha knockout mice

31 March 2020

1 reference

Tumour necrosis factor in man: clinical and biological observations

31 March 2020

1 reference

A phase I clinical trial of recombinant human tumor necrosis factor

31 March 2020

1 reference

Phase I study of recombinant human tumor necrosis factor

31 March 2020

1 reference

Isolated limb perfusion with melphalan and TNF-alpha in the treatment of extremity sarcoma

31 March 2020

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Outcome and prognostic factor analysis of 217 consecutive isolated limb perfusions with tumor necrosis factor-alpha and melphalan for limb-threatening soft tissue sarcoma

31 March 2020

1 reference

Coley's toxins in perspective

31 March 2020

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Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line

31 March 2020

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Regulation of tumor necrosis factor gene expression in colorectal adenocarcinoma: in vivo analysis by in situ hybridization

31 March 2020

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In situ detection of tumour necrosis factor in human ovarian cancer specimens

31 March 2020

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Tumor necrosis factor and its receptors in human ovarian cancer. Potential role in disease progression

31 March 2020

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Interleukin-6, tumour necrosis factor alpha and interleukin-1beta in patients with renal cell carcinoma

31 March 2020

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Tumour necrosis factor-alpha, interleukin-6, and fasting serum insulin correlate with clinical outcome in metastatic breast cancer patients treated with chemotherapy

31 March 2020

1 reference

Tumor necrosis factor-alpha in the pathogenesis and treatment of cancer

31 March 2020

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Elevation of cytokine levels in cachectic patients with prostate carcinoma

31 March 2020

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Serum levels of IL-6 and TNF- correlate with clinicopathological features and patient survival in patients with prostate cancer

31 March 2020

1 reference

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo

31 March 2020

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Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

31 March 2020

1 reference

Paradoxical effects of tumour necrosis factor in experimental ovarian cancer

31 March 2020

1 reference

Cells secreting tumour necrosis factor show enhanced metastasis in nude mice

31 March 2020

1 reference

Enhancement of experimental metastasis by tumor necrosis factor

31 March 2020

1 reference

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

31 March 2020

1 reference

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune re

31 March 2020

1 reference

Inflammation and cancer: back to Virchow?

31 March 2020

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Smoldering and polarized inflammation in the initiation and promotion of malignant disease

31 March 2020

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Cancer-related inflammation

31 March 2020

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The inflammatory cytokine tumor necrosis factor-alpha generates an autocrine tumor-promoting network in epithelial ovarian cancer cells

31 March 2020

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Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasis

31 March 2020

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Tumor necrosis factor-alpha promotes malignant pleural effusion

31 March 2020

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Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway.

31 March 2020

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Low levels of tumor necrosis factor alpha increase tumor growth by inducing an endothelial phenotype of monocytes recruited to the tumor site

31 March 2020

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Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK.

31 March 2020

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Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype

31 March 2020

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Expression and regulation of tumor necrosis factor alpha in normal and malignant ovarian epithelium

31 March 2020

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von Hippel-Lindau protein-mediated repression of tumor necrosis factor alpha translation revealed through use of cDNA arrays

31 March 2020

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IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

31 March 2020

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Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells.

31 March 2020

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TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.

31 March 2020

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Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation

31 March 2020

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Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis

31 March 2020

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Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma

31 March 2020

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Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids

31 March 2020

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Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour development

31 March 2020

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Spontaneous regression of lung metastasis in the absence of tumor necrosis factor receptor p55

31 March 2020

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Regulatory T cells and treatment of cancer

31 March 2020

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Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells.

31 March 2020

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

31 March 2020

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Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

31 March 2020

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The two NF-kappaB activation pathways and their role in innate and adaptive immunity

31 March 2020

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IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

31 March 2020

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Proinflammatory CD4+ CD45RB(hi) lymphocytes promote mammary and intestinal carcinogenesis in Apc(Min/+) mice.

31 March 2020

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Infliximab chimeric antitumor necrosis factor-a monoclonal antibody as potential treatment for myelodysplastic syndromes.

31 March 2020

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Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

31 March 2020

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Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

31 March 2020

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IL-23 promotes tumour incidence and growth

31 March 2020

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New TNF-alpha releasing inhibitors as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and sulindac or tamoxifen

31 March 2020

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Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials

31 March 2020

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Malignancy and biologic therapy in rheumatoid arthritis

31 March 2020

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TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity

31 March 2020

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BCG immunotherapy of bladder cancer: 20 years on.

31 March 2020

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"Re-educating" tumor-associated macrophages by targeting NF-kappaB.

31 March 2020

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Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

31 March 2020

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Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

31 March 2020

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Adaptive immunity maintains occult cancer in an equilibrium state

31 March 2020

1 reference

TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors

31 March 2020

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Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.

31 March 2020

1 reference

Single-chain TNF, a TNF derivative with enhanced stability and antitumoral activity

31 March 2020

1 reference

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

31 March 2020

1 reference

Tumor necrosis factor-alpha blocks apoptosis in melanoma cells when BRAF signaling is inhibited

31 March 2020

1 reference

Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma

31 March 2020

1 reference

Tumor necrosis factor: an apoptosis JuNKie?

31 March 2020

1 reference

Signalling pathways of the TNF superfamily: a double-edged sword

31 March 2020

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Toll-like receptor signalling

31 March 2020

1 reference

Tumor necrosis factor alpha is a determinant of pathogenesis and disease progression in mycobacterial infection in the central nervous system

31 March 2020

1 reference

Both lymphotoxin-alpha and TNF are crucial for control of Toxoplasma gondii in the central nervous system

31 March 2020

1 reference

Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor

31 March 2020

1 reference

Novel tumor necrosis factor-knockout mice that lack Peyer's patches

31 March 2020

1 reference

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

31 March 2020

1 reference

Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis

31 March 2020

1 reference

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis

31 March 2020

1 reference

Anti-TNF antibody treatment of Crohn's disease

31 March 2020

1 reference

Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial

31 March 2020

1 reference

Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trial

31 March 2020

1 reference

Evidence of a role of tumor necrosis factor alpha in refractory asthma

31 March 2020

1 reference

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

31 March 2020

1 reference

Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein

31 March 2020

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31 March 2020

Inflammation and cancer

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Constitutive expression and role of the TNF family ligands in apoptotic killing of tumor cells by human NK cells

31 March 2020

1 reference

12 December 2020

Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis

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12 December 2020

Phase I study of recombinant tumor necrosis factor in cancer patients.

1 reference

12 December 2020

The treatment of malignant tumors by bacterial toxins as developed by the late William B. Coley, M.D., reviewed in the light of modern research

1 reference

12 December 2020

Human lymphotoxin. Production by a lymphoblastoid cell line, purification, and initial characterization

1 reference

12 December 2020

The Treatment of Inoperable Sarcoma by Bacterial Toxins (the Mixed Toxins of the Streptococcus erysipelas and the Bacillus prodigiosus).

1 reference

12 December 2020

The role of tumor necrosis factor in health and disease.

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12 December 2020

TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice

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12 December 2020

Serum levels of tumor necrosis factor-alpha and nutritional status in pancreatic cancer patients

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12 December 2020

Amplified expression of tumor necrosis factor receptor in cells transfected with Epstein-Barr virus shuttle vector cDNA libraries

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12 December 2020

Tumor necrosis factor acts as a tumor promoter in BALB/3T3 cell transformation

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12 December 2020

Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer

1 reference

12 December 2020

Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice.

1 reference

12 December 2020

Characterization of the antitumor activities of human tumor necrosis factor-alpha and the comparison with other cytokines: induction of tumor-specific immunity

1 reference

12 December 2020

Rapid killing of actinomycin D-treated tumor cells by human mononuclear cells. I. Effectors belong to the monocyte-macrophage lineage.

1 reference

12 December 2020

Essential roles of tumor necrosis factor receptor p55 in liver metastasis of intrasplenic administration of colon 26 cells

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12 December 2020

Synergistic cytotoxic and antitumor effects of recombinant human tumor necrosis factor and hyperthermia

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12 December 2020

Human tumor xenografts treated with recombinant human tumor necrosis factor alone or in combination with interferons

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12 December 2020

Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors

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12 December 2020

Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein

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12 December 2020

A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity.

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12 December 2020

Immunomodulatory properties of recombinant murine and human tumor necrosis factor

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12 December 2020

An anti-tumor necrosis factor-alpha antibody inhibits the development of experimental skin tumors

1 reference

12 December 2020

The clinical significance of tumor necrosis factor-alpha plasma level in patients having chronic lymphocytic leukemia

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12 December 2020

Preparations of lymphotoxin induce resistance to their own cytotoxic effect

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12 December 2020

Human tumor necrosis factor. Production, purification, and characterization

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12 December 2020

Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis.

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12 December 2020

Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects.

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12 December 2020

The treatment of malignant tumors by repeated inoculations of erysipelas. With a report of ten original cases. 1893.

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12 December 2020

Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis

1 reference

12 December 2020

A review of the influence of bacterial infection and of bacterial products (Coley's toxins) on malignant tumors in man; a critical analysis of 30 inoperable cases treated by Coley's mixed toxins, in which diagnosis was confirmed by microscopic exam

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12 December 2020

Prerequisites for effective isolated limb perfusion using tumour necrosis factor alpha and melphalan in rats

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12 December 2020

Journal of the National Cancer Institute, Vol. 29, 1962: Action of bacterial polysaccharide on tumors. II. Damage of sarcoma 37 by serum of mice treated with Serratia marcescens polysaccharide, and induced tolerance.

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12 December 2020

Carcinogenic role of tumor necrosis factor-alpha inducing protein of Helicobacter pylori in human stomach

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12 December 2020

Lymphocyte in vitro cytotoxicity: mechanisms of immune and non-immune small lymphocyte mediated target L cell destruction

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12 December 2020

Primary structure of human lymphotoxin derived from 1788 lymphoblastoid cell line

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12 December 2020