The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication (Q61800834)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30718749%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

title

The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30718749%20AND%20SRC:MED&resulttype=core&format=json

Herpes simplex virus type 1

21 April 2020

main subject

1 reference

1 reference

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21 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30718749%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

Mark Slevin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30718749%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

Eugen Petcu

series ordinal

1 reference

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21 April 2020

language of work or name

English

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publication date

4 February 2019

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21 April 2020

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21 April 2020

volume

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21 April 2020

issue

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21 April 2020

page(s)

1260

1 reference

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Creative Commons Attribution 4.0 International

21 April 2020

start time

4 February 2019

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

cites work

Global and Regional Estimates of Prevalent and Incident Herpes Simplex Virus Type 1 Infections in 2012.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Isolation and Characterization of Acyclovir-resistant Mutants of Herpes Simplex Virus

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

A Highly Efficacious Herpes Simplex Virus 1 Vaccine Blocks Viral Pathogenesis and Prevents Corneal Immunopathology via Humoral Immunity

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Adeno-Associated Virus (AAV) as a Vector for Gene Therapy.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

The regulation of cyclin-dependent kinase 5 activity through the metabolism of p35 or p39 Cdk5 activator

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Structure and regulation of the CDK5-p25(nck5a) complex

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Cdk5 Directly Targets Nuclear p21CIP1 and Promotes Cancer Cell Growth

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Inhibition of cyclin-dependent kinases by p21

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Peptides derived from Cdk5 activator p35, specifically inhibit deregulated activity of Cdk5.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Internal ribosome entry sites (IRESs): reality and use.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Cdks, cyclins and CKIs: roles beyond cell cycle regulation

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Role of a cdk5-associated protein, p35, in herpes simplex virus type 1 replicationin vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Specific inhibition of p25/Cdk5 activity by the Cdk5 inhibitory peptide reduces neurodegeneration in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Cdk5 phosphorylates p53 and regulates its activity

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Requirement for cellular cyclin-dependent kinases in herpes simplex virus replication and transcription

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Neuronal cell cycle: the neuron itself and its circumstances

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Herpes simplex virus 1 upregulates p35, alters CDK-5 localization, and stimulates CDK-5 kinase activity during acute infection in neurons

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Disruption of the p53-p21 pathway inhibits efficiency of the lytic-replication cycle of herpes simplex virus type 2 (HSV-2).

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Herpes simplex virus type 1 ICP0 protein does not accumulate in the nucleus of primary neurons in culture

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Recombinant adeno-associated viral vector production and purification.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Live visualization of herpes simplex virus type 1 compartment dynamics

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Comparison of total and cytoplasmic mRNA reveals global regulation by nuclear retention and miRNAs

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-37989-3

7 January 2021

Transactivation of herpes simplex virus type 1 immediate-early gene expression by virion-associated factors is blocked by an inhibitor of cyclin-dependent protein kinases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30718749

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41598-018-37989-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30718749%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30718749%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

PubMed publication ID

30718749

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30718749%20AND%20SRC:MED&resulttype=core&format=json