Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic approaches (Q61805577)

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scientific article published on 31 January 2019

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English	Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic approaches	scientific article published on 31 January 2019

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Europe PubMed Central

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6355021

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30703166%20AND%20SRC:MED&resulttype=core&format=json

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21 April 2020

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25 July 2020

title

Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic approaches (English)

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Europe PubMed Central

PMC publication ID

6355021

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30703166%20AND%20SRC:MED&resulttype=core&format=json

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21 April 2020

main subject

eukaryote

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PubMed

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22 October 2019

antifungal drug resistance

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PubMed

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25 July 2020

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author

Dominique Sanglard

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1

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Europe PubMed Central

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6355021

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30703166%20AND%20SRC:MED&resulttype=core&format=json

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Dominique Sanglard

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Dominique Sanglard

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English

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publication date

31 January 2019

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Europe PubMed Central

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6355021

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30703166%20AND%20SRC:MED&resulttype=core&format=json

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21 April 2020

1 January 2019

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PubMed Central

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25 July 2020

published in

PLOS Pathogens

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PubMed Central

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22 October 2019

stated in

Europe PubMed Central

PMC publication ID

6355021

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30703166%20AND%20SRC:MED&resulttype=core&format=json

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21 April 2020

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PubMed Central

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25 July 2020

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15

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Europe PubMed Central

PMC publication ID

6355021

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30703166%20AND%20SRC:MED&resulttype=core&format=json

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21 April 2020

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1

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Europe PubMed Central

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6355021

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21 April 2020

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e1007478

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6355021

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Creative Commons Attribution 4.0 International

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Europe PubMed Central

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22 October 2019

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Europe PubMed Central

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25 July 2020

cites work

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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The art and design of genetic screens: yeast

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Aneuploidy and isochromosome formation in drug-resistant Candida albicans

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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A genome-wide view of the spectrum of spontaneous mutations in yeast.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging

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12 December 2020

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Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata

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Discovery of a HapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossing

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https://pubmed.ncbi.nlm.nih.gov/30703166

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Expression quantitative trait loci: present and future

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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inferred from PubMed ID database lookup

Mutation rates, spectra, and genome-wide distribution of spontaneous mutations in mismatch repair deficient yeast

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of a fungus-specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Fitness trade-offs restrict the evolution of resistance to amphotericin B

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Mapping the cellular response to small molecules using chemogenomic fitness signatures

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Genetic and phenotypic intra-species variation in Candida albicans

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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The evolution of drug resistance in clinical isolates of Candida albicans

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systematic functional profiling of transcription factor networks in Cryptococcus neoformans

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Genetic Analysis Using an Isogenic Mating Pair of Aspergillus fumigatus Identifies Azole Resistance Genes and Lack of MAT Locus's Role in Virulence

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Next-generation sequencing offers new insights into the resistance of Candida spp. to echinocandins and azoles.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Mismatch Repair Mutants

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Genome-Wide Association Study Identifies Novel Candidate Genes for Aggressiveness, Deoxynivalenol Production, and Azole Sensitivity in Natural Field Populations of Fusarium graminearum.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Emerging Threats in Antifungal-Resistant Fungal Pathogens

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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CRISPR-Cas9, the new kid on the block of fungal molecular biology.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Multilocus resistance evolution to azole fungicides in fungal plant pathogen populations.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Global Population Genetic Analysis of Aspergillus fumigatus

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Impact of ERG3 mutations and expression of ergosterol genes controlled by UPC2 and NDT80 in Candida parapsilosis azole resistance.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of genetic markers of resistance to echinocandins, azoles and 5-fluorocytosine in Candida glabrata by next-generation sequencing: a feasibility study.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Genome-Wide Association Studies In Plant Pathosystems: Toward an Ecological Genomics Approach

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of C-5 Sterol Desaturase Activity Results in Increased Resistance to Azole and Echinocandin Antifungals in a Clinical Isolate of Candida parapsilosis.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative Genomics of Two Sequential Candida glabrata Clinical Isolates.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Monitoring Antifungal Resistance in a Global Collection of Invasive Yeasts and Molds: Application of CLSI Epidemiological Cutoff Values and Whole-Genome Sequencing Analysis for Detection of Azole Resistance in Candida albicans

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Comparative genomic and transcriptomic analyses unveil novel features of azole resistance and adaptation to the human host in Candida glabrata

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Nature's genetic screens: using genome-wide association studies for effector discovery

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Patterns of Genomic Variation in the Opportunistic Pathogen Candida glabrata Suggest the Existence of Mating and a Secondary Association with Humans

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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In-host microevolution of Aspergillus fumigatus: A phenotypic and genotypic analysis.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Genome evolution across 1,011 Saccharomyces cerevisiae isolates

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Worldwide emergence of resistance to antifungal drugs challenges human health and food security

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Epidemiology of Candida auris in Colombia Reveals a Highly Related, Countrywide Colonization With Regional Patterns in Amphotericin B Resistance

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Gene flow contributes to diversification of the major fungal pathogen Candida albicans.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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MARDy: Mycology Antifungal Resistance Database

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

based on heuristic

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Evolution of drug resistance in an antifungal-naive chronic infection

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30703166

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12 December 2020

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Identifiers

DOI

10.1371/JOURNAL.PPAT.1007478

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Europe PubMed Central

PMC publication ID

6355021

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30703166%20AND%20SRC:MED&resulttype=core&format=json

retrieved

21 April 2020

PMC publication ID

6355021

1 reference

stated in

Europe PubMed Central

PMC publication ID

6355021

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30703166%20AND%20SRC:MED&resulttype=core&format=json

retrieved

21 April 2020

PubMed publication ID

30703166

1 reference

stated in

Europe PubMed Central

PMC publication ID

6355021

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30703166%20AND%20SRC:MED&resulttype=core&format=json

retrieved

21 April 2020

 

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