Analysis of a fungus-specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation (Q48026484)

7 February 2018

title

Analysis of a fungus-specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation (English)

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7 February 2018

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Joachim Morschhäuser

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7 February 2018

author name string

Rebecca Schillig

series ordinal

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7 February 2018

language of work or name

English

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publication date

25 July 2013

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7 February 2018

published in

Molecular Microbiology

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7 February 2018

volume

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7 February 2018

issue

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7 February 2018

page(s)

1003-1017

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7 February 2018

Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers.

cites work

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The zinc cluster transcription factor Ahr1p directs Mcm1p regulation of Candida albicans adhesion

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An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis

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CTA4 transcription factor mediates induction of nitrosative stress response in Candida albicans.

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Identifying transcription factor functions and targets by phenotypic activation

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Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates

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TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.

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Divergent functions of three Candida albicans zinc-cluster transcription factors (CTA4, ASG1 and CTF1) complementing pleiotropic drug resistance in Saccharomyces cerevisiae

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Functional analysis of cis- and trans-acting elements of the Candida albicans CDR2 promoter with a novel promoter reporter system.

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An artificial transcription activator mimics the genome-wide properties of the yeast Pdr1 transcription factor

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A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate.

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Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans

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A general strategy to uncover transcription factor properties identifies a new regulator of drug resistance in yeast.

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A phenotypic profile of the Candida albicans regulatory network

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Reductive iron uptake by Candida albicans: role of copper, iron and the TUP1 regulator

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New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system.

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Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis

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Genome-wide expression and location analyses of the Candida albicans Tac1p regulon.

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Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes

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A fungal family of transcriptional regulators: the zinc cluster proteins

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DNA recognition by GAL4: structure of a protein-DNA complex.

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Transcriptional rewiring of fungal galactose-metabolism circuitry

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A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance

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Regulation of multidrug resistance in pathogenic fungi

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The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans

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Gene annotation and drug target discovery in Candida albicans with a tagged transposon mutant collection

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A family of oligopeptide transporters is required for growth of Candida albicans on proteins

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The SAT1 flipper, an optimized tool for gene disruption in Candida albicans

21 January 2018

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The transcription factor Ndt80 does not contribute to Mrr1-, Tac1-, and Upc2-mediated fluconazole resistance in Candida albicans

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White-opaque switching of Candida albicans allows immune evasion in an environment-dependent fashion

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Gain-of-function mutations in the transcription factor MRR1 are responsible for overexpression of the MDR1 efflux pump in fluconazole-resistant Candida dubliniensis strains

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Regulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans

21 January 2018

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Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1.

21 January 2018

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Role of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolism

21 January 2018

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Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance

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Novel fungal transcriptional activators, Cmr1p of Colletotrichum lagenarium and pig1p of Magnaporthe grisea, contain Cys2His2 zinc finger and Zn(II)2Cys6 binuclear cluster DNA-binding motifs and regulate transcription of melanin biosynthesis genes i

21 January 2018

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In vivo systematic analysis of Candida albicans Zn2-Cys6 transcription factors mutants for mice organ colonization

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Identification and functional characterization of Rca1, a transcription factor involved in both antifungal susceptibility and host response in Candida albicans

21 January 2018

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The zinc cluster transcription factor Tac1p regulates PDR16 expression in Candida albicans

21 January 2018

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Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance

21 January 2018

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Interlocking transcriptional feedback loops control white-opaque switching in Candida albicans

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/MMI.12327

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7 February 2018

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7 February 2018