Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastoma (Q60819945)

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23 January 2020

title

Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastoma (English)

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23 January 2020

Wen Fong Ooi

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23 January 2020

Valentina Canella

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Natalia Arseni

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Valentina Adami

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23 January 2020

Giulia Guarguaglini

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23 January 2020

Maria Giubettini

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23 January 2020

Sara Stigliani

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23 January 2020

Gian Paolo Tonini

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23 January 2020

publication date

15 February 2012

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Genes, Chromosomes and Cancer

23 January 2020

published in

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volume

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issue

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page(s)

545-556

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International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee

23 January 2020

cites work

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7 January 2021

Metaphase chromosome anomaly: association with drug resistance and cell-specific products

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7 January 2021

Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastoma

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7 January 2021

High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: four cases of homozygous deletions of the CDKN2A gene

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7 January 2021

High-risk neuroblastoma tumors with 11q-deletion display a poor prognostic, chromosome instability phenotype with later onset

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7 January 2021

Spatial control of mitosis by the GTPase Ran

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7 January 2021

Spatial and temporal coordination of mitosis by Ran GTPase

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7 January 2021

The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report

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7 January 2021

RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma

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7 January 2021

Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity.

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7 January 2021

Integrated genomic profiling identifies two distinct molecular subtypes with divergent outcome in neuroblastoma with loss of chromosome 11q

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7 January 2021

A second generation human haplotype map of over 3.1 million SNPs

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7 January 2021

Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays

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7 January 2021

RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.

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7 January 2021

Microarray analyses reveal strong influence of DNA copy number alterations on the transcriptional patterns in pancreatic cancer: implications for the interpretation of genomic amplifications

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7 January 2021

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

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7 January 2021

Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint.

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7 January 2021

RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis

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7 January 2021

Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

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7 January 2021

HURP is part of a Ran-dependent complex involved in spindle formation

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7 January 2021

Identification of candidate genes involved in neuroblastoma progression by combining genomic and expression microarrays with survival data.

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7 January 2021

Integrative analysis reveals the direct and indirect interactions between DNA copy number aberrations and gene expression changes

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7 January 2021

Modeling genomic diversity and tumor dependency in malignant melanoma

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7 January 2021

LY6K is a novel molecular target in bladder cancer on basis of integrate genome-wide profiling

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7 January 2021

Oligonucleotide microarray analysis of gene expression in neuroblastoma displaying loss of chromosome 11q.

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7 January 2021

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

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7 January 2021

Genome wide measurement of DNA copy number changes in neuroblastoma: dissecting amplicons and mapping losses, gains and breakpoints

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7 January 2021

ArrayCGH-based classification of neuroblastoma into genomic subgroups

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7 January 2021

Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells

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7 January 2021

Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma

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7 January 2021

Neuroblastomas have distinct genomic DNA profiles that predict clinical phenotype and regional gene expression

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7 January 2021

Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis

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7 January 2021

The spindle-assembly checkpoint in space and time

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7 January 2021

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

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7 January 2021

Customized Oligonucleotide Microarray Gene Expression–Based Classification of Neuroblastoma Patients Outperforms Current Clinical Risk Stratification

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7 January 2021

Prognostic impact of gene expression-based classification for neuroblastoma.

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7 January 2021

Identification and characterization of DNA imbalances in neuroblastoma by high-resolution oligonucleotide array comparative genomic hybridization

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7 January 2021

Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling.

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7 January 2021

Aurora A is a negative prognostic factor and a new therapeutic target in human neuroblastoma

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7 January 2021

Cyclin-dependent kinase pathways as targets for cancer treatment

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7 January 2021

HURP Is a Ran-Importin β-Regulated Protein that Stabilizes Kinetochore Microtubules in the Vicinity of Chromosomes

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7 January 2021

Are gains of chromosomal regions 7q and 11p important abnormalities in neuroblastoma?

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7 January 2021

Discovering statistically significant biclusters in gene expression data

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7 January 2021

Novel risk stratification of patients with neuroblastoma by genomic signature, which is independent of molecular signature

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7 January 2021

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

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7 January 2021

Comparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide single nucleotide polymorphism array analysis.

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7 January 2021

Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number

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7 January 2021

HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture.

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7 January 2021

Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death

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7 January 2021

Messenger RNA translation state: the second dimension of high-throughput expression screening

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7 January 2021

Identifiers

DOI

10.1002/GCC.21940

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23 January 2020

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