Cytokine Regulation in Human CD4 T Cells by the Aryl Hydrocarbon Receptor and Gq-Coupled Receptors. (Q64943300)

1 July 2019

title

Cytokine Regulation in Human CD4 T Cells by the Aryl Hydrocarbon Receptor and Gq-Coupled Receptors. (English)

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1 July 2019

author name string

Jeremy P McAleer

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1 July 2019

Jun Fan

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1 July 2019

Bryanna Roar

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1 July 2019

Donald A Primerano

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1 July 2019

James Denvir

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1 July 2019

language of work or name

English

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publication date

19 July 2018

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1 July 2019

published in

Scientific Reports

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1 July 2019

volume

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1 July 2019

issue

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1 July 2019

page(s)

10954

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1 July 2019

Creative Commons Attribution 4.0 International

start time

19 July 2018

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April 2022 Public Data File from Crossref

copyrighted

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describes a project that uses

DESeq2

object named as

DESeq

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

Differentiation of effector CD4 T cell populations (*)

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Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

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Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

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Interleukin 17 Family Cytokines: Signaling Mechanisms, Biological Activities, and Therapeutic Implications

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Therapeutic opportunities of the IL-22-IL-22R1 system

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Directing traffic: IL-17 and IL-22 coordinate pulmonary immune defense

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Interleukin-10-deficient mice develop chronic enterocolitis

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Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

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The aryl hydrocarbon receptor: multitasking in the immune system

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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

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Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

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Regulation of inflammation by extracellular acidification and proton-sensing GPCRs

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Deficiency of the G protein Gαq ameliorates experimental autoimmune encephalomyelitis with impaired DC-derived IL-6 production and Th17 differentiation

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Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

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Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells

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Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells.

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TGF-β1 signaling plays a dominant role in the crosstalk between TGF-β1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells

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Cell-specific regulation of human aryl hydrocarbon receptor expression by transforming growth factor-beta(1).

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

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IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

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Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

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Polycyclic aromatic hydrocarbons reciprocally regulate IL-22 and IL-17 cytokines in peripheral blood mononuclear cells from both healthy and asthmatic subjects

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7 January 2021

Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells

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7 January 2021

Interleukin-21 suppresses the differentiation and functions of T helper 2 cells.

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7 January 2021

IL-21 induces IL-22 production in CD4+ T cells.

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Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling.

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CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator

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Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

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Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis

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Circulating Th17, Th22, and Th1 cells are increased in psoriasis

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7 January 2021

Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions

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Identification of early gene expression changes during human Th17 cell differentiation.

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Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T Cells

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7 January 2021

TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy

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Regional and mucosal memory T cells

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Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells

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7 January 2021

T Lymphocytes Expressing AlphaE Beta7 Integrin in Ulcerative Colitis: Associations With Cellular Lineage and Phenotype

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7 January 2021

Aryl hydrocarbon receptor activation affects the dendritic cell phenotype and function during allergic sensitization

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7 January 2021

ANKRD13C acts as a molecular chaperone for G protein-coupled receptors

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Differential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo

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7 January 2021

Role and species-specific expression of colon T cell homing receptor GPR15 in colitis

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7 January 2021

The orphan receptor GPR55 is a novel cannabinoid receptor

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7 January 2021

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

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7 January 2021

The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment

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The GPR55 antagonist CID16020046 protects against intestinal inflammation.

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The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

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Extracellular acidification stimulates IL-6 production and Ca(2+) mobilization through proton-sensing OGR1 receptors in human airway smooth muscle cells.

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Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

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Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.

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G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation

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OGR1/GPR68 Modulates the Severity of Experimental Autoimmune Encephalomyelitis and Regulates Nitric Oxide Production by Macrophages

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7 January 2021

Dysregulation of proinflammatory versus anti-inflammatory human TH17 cell functionalities in the autoinflammatory Schnitzler syndrome

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RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

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7 January 2021

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

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https://api.crossref.org/works/10.1038%2FS41598-018-29262-4

7 January 2021

IL-17 and GM-CSF expression are antagonistically regulated by human T helper cells.

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https://api.crossref.org/works/10.1038%2FS41598-018-29262-4

7 January 2021

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.

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https://api.crossref.org/works/10.1038%2FS41598-018-29262-4

7 January 2021

Gq-Coupled Receptors in Autoimmunity

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https://api.crossref.org/works/10.1038%2FS41598-018-29262-4

7 January 2021

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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7 January 2021

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HISAT: a fast spliced aligner with low memory requirements

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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

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Effect of transforming growth factor-beta1 on expression of aryl hydrocarbon receptor and genes of Ah gene battery: clues for independent down-regulation in A549 cells

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PubMed

https://pubmed.ncbi.nlm.nih.gov/30026493

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αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis

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PubMed

https://pubmed.ncbi.nlm.nih.gov/30026493

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41598-018-29262-4

1 reference

1 July 2019

Dimensions Publication ID

0 references

1 reference

1 July 2019

PubMed publication ID

30026493

1 reference

1 July 2019