Cathepsins S, B and L with aminopeptidases display β-secretase activity associated with the pathogenesis of Alzheimer's disease. (Q53319143)

13 May 2018

title

Cathepsins S, B and L with aminopeptidases display β-secretase activity associated with the pathogenesis of Alzheimer's disease. (English)

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13 May 2018

author name string

Israel Schechter

series ordinal

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13 May 2018

Etty Ziv

series ordinal

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13 May 2018

publication date

1 April 2011

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13 May 2018

published in

Biological Chemistry

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13 May 2018

volume

392

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13 May 2018

issue

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13 May 2018

page(s)

555-569

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13 May 2018

Isoaspartate-containing amyloid precursor protein-derived peptides alter efficacy and specificity of potential beta-secretases

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Cysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeutics

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Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein

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Kinetic properties of cathepsin D and BACE 1 indicate the need to search for additional beta-secretase candidate(s).

21 January 2018

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Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology

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21 January 2018

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

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The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry

21 January 2018

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

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Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2011.054

21 January 2018

Identifiers

DOI

10.1515/BC.2011.054

1 reference

13 May 2018

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13 May 2018