Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster. (Q52581484)

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scientific article published on 17 April 2018

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English	Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster.	scientific article published on 17 April 2018

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Europe PubMed Central

PubMed publication ID

29667128

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3 May 2018

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http://europepmc.org/abstract/MED/29667128

title

Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster. (English)

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PubMed publication ID

29667128

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main subject

Drosophila melanogaster

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neurodegeneration

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author

Carlos Velez-Pardo

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Carlos Velez-Pardo

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Daniel A Martinez-Perez

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29667128

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http://europepmc.org/abstract/MED/29667128

Marlene Jimenez-Del-Rio

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2

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29667128

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publication date

17 April 2018

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29667128

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Neurotoxicity Research

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PubMed publication ID

29667128

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http://europepmc.org/abstract/MED/29667128

cites work

Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical

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A novel Cys212Tyr founder mutation in parkin and allelic heterogeneity of juvenile Parkinsonism in a population from North West Colombia.

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12 December 2020

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Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate.

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Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

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12 December 2020

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DJ-1 has a role in antioxidative stress to prevent cell death

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Autosomal recessive juvenile parkinsonism Cys212Tyr mutation in parkin renders lymphocytes susceptible to dopamine- and iron-mediated apoptosis.

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Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells

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The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

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12 December 2020

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Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster.

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Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1

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Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice

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12 December 2020

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Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila

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12 December 2020

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Antioxidant properties of minocycline: neuroprotection in an oxidative stress assay and direct radical-scavenging activity

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction.

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12 December 2020

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Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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Paraquat-induced oxidative stress in drosophila melanogaster: effects of melatonin, glutathione, serotonin, minocycline, lipoic acid and ascorbic acid.

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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A new evolutionary paradigm for the Parkinson disease gene DJ-1

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12 December 2020

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Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice

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PubMed

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12 December 2020

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Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits

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12 December 2020

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Complex I is the major site of mitochondrial superoxide production by paraquat

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12 December 2020

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Genotypic and phenotypic characteristics of Dutch patients with early onset Parkinson's disease.

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12 December 2020

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Free radicals generated during oxidation of green tea polyphenols: electron paramagnetic resonance spectroscopy combined with density functional theory calculations.

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12 December 2020

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Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice

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12 December 2020

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The effects of polyphenols on survival and locomotor activity in Drosophila melanogaster exposed to iron and paraquat.

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12 December 2020

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Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1beta mutants

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12 December 2020

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Rotenone, paraquat, and Parkinson's disease

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12 December 2020

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DJ-1 mediates paraquat-induced dopaminergic neuronal cell death.

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12 December 2020

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Life span and locomotor activity modification by glucose and polyphenols in Drosophila melanogaster chronically exposed to oxidative stress-stimuli: implications in Parkinson's disease.

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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The role of antioxidant versus pro‐oxidant effects of green tea polyphenols in cancer prevention

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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Acute and chronic metal exposure impairs locomotion activity in Drosophila melanogaster: a model to study Parkinsonism.

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The history of the tetracyclines

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12 December 2020

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Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

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12 December 2020

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Conservation of oxidative protein stabilization in an insect homologue of parkinsonism-associated protein DJ-1

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12 December 2020

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DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats

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12 December 2020

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Evaluation of the antioxidant activity of tetracycline antibiotics in vitro

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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The Protective Effect of Minocycline in a Paraquat-Induced Parkinson's Disease Model in Drosophila is Modified in Altered Genetic Backgrounds

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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Parkinsonism due to mutations in PINK1, parkin, and DJ-1 and oxidative stress and mitochondrial pathways

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12 December 2020

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Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism.

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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What is behind the non-antibiotic properties of minocycline?

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12 December 2020

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Minocycline effect on life and health span of Drosophila melanogaster

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12 December 2020

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Antioxidant compound supplementation prevents oxidative damage in a Drosophila model of Parkinson's disease.

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12 December 2020

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Acute exposure of Drosophila melanogaster to paraquat causes oxidative stress and mitochondrial dysfunction.

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https://pubmed.ncbi.nlm.nih.gov/29667128

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12 December 2020

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Drosophila DJ-1 decreases neural sensitivity to stress by negatively regulating Daxx-like protein through dFOXO.

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12 December 2020

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Neuroprotective function of DJ-1 in Parkinson's disease

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12 December 2020

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Minocycline, but not ascorbic acid, increases motor activity and extends the life span of Drosophila melanogaster.

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How to calculate sample size for different study designs in medical research?

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RNAi screening in Drosophila cells and in vivo.

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Quantitative analysis of major constituents in green tea with different plucking periods and their antioxidant activity

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Analysis of dopaminergic neuronal dysfunction in genetic and toxin-induced models of Parkinson's disease in Drosophila.

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12 December 2020

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A dopamine receptor contributes to paraquat-induced neurotoxicity in Drosophila.

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Flavonoid-based therapies in the early management of neurodegenerative diseases

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Chemistry of lipid peroxidation products and their use as biomarkers in early detection of diseases

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12 December 2020

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Tea Polyphenols in Parkinson's Disease

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12 December 2020

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Pro-oxidant activity of polyphenols and its implication on cancer chemoprevention and chemotherapy

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12 December 2020

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Oxidative stress and Parkinson's disease

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12 December 2020

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Reactivity of phenolic compounds towards free radicals under in vitro conditions

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12 December 2020

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Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat

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The Concept of Prodromal Parkinson's Disease

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Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View

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The translational relevance of Drosophila in drug discovery

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12 December 2020

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Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG)

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12 December 2020

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Therapeutic effects of EGCG: a patent review

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Neuroprotective and Therapeutic Strategies against Parkinson's Disease: Recent Perspectives

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The clinical symptoms of Parkinson's disease

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Ayurvedic Amalaki Rasayana promotes improved stress tolerance and thus has anti-aging effects in Drosophila melanogaster

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12 December 2020

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Knockdown transgenic Lrrk Drosophila resists paraquat-induced locomotor impairment and neurodegeneration: A therapeutic strategy for Parkinson's disease.

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The MPTP Story

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Minocycline protects, rescues and prevents knockdown transgenic parkin Drosophila against paraquat/iron toxicity: Implications for autosomic recessive juvenile parkinsonism.

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Identification of potential therapeutic compounds for Parkinson's disease using Drosophila and human cell models.

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DJ-1/PARK7: A New Therapeutic Target for Neurodegenerative Disorders

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Genetics of Parkinson's Disease: Genotype-Phenotype Correlations

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Neuropathology of Parkinson disease

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Paraquat-Induced Movement Disorder in Relation to Oxidative Stress-Mediated Neurodegeneration in the Brain of Drosophila melanogaster

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Identifiers

DOI

10.1007/S12640-018-9899-X

1 reference

stated in

Europe PubMed Central

PubMed publication ID

29667128

retrieved

3 May 2018

reference URL

http://europepmc.org/abstract/MED/29667128

PubMed publication ID

29667128

1 reference

stated in

Europe PubMed Central

PubMed publication ID

29667128

retrieved

3 May 2018

reference URL

http://europepmc.org/abstract/MED/29667128

 

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