Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity. (Q52575826)

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scientific article published on 21 December 2006

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English	Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity.	scientific article published on 21 December 2006

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scholarly article

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23 December 2019

Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity (English)

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23 December 2019

human eosinophil

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Thomas E DeCoursey

6

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23 December 2019

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Deri Morgan

1

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23 December 2019

Vladimir V Cherny

2

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23 December 2019

Alison Finnegan

3

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23 December 2019

James Bollinger

4

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23 December 2019

Michael H Gelb

5

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23 December 2019

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21 December 2006

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23 December 2019

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18

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Journal of Physiology

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23 December 2019

579

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23 December 2019

Pt 2

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23 December 2019

327-344

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23 December 2019

Role of nucleotides and phosphoinositides in the stability of electron and proton currents associated with the phagocytic NADPH oxidase.

1 reference

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Intracellular actions of group IIA secreted phospholipase A2 and group IVA cytosolic phospholipase A2 contribute to arachidonic acid release and prostaglandin production in rat gastric mucosal cells and transfected human embryonic kidney cells

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Cytosolic phospholipase A2 enzymes are not required by mouse bone marrow-derived macrophages for the control of Mycobacterium tuberculosis in vitro

1 reference

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2 November 2018

Charge compensation during the phagocyte respiratory burst

1 reference

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2 November 2018

Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid

1 reference

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2 November 2018

Regulation and termination of NADPH oxidase activity

1 reference

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2 November 2018

Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase

1 reference

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Epidermal growth factor inhibits 14C-alpha-methyl-D-glucopyranoside uptake in renal proximal tubule cells: involvement of PLC/PKC, p44/42 MAPK, and cPLA2.

1 reference

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2 November 2018

Inhibition of formyl-methionyl-leucyl-phenylalanine-stimulated respiratory burst in human neutrophils by adrenaline: inhibition of Phospholipase A2 activity but not p47phox phosphorylation and translocation

1 reference

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2 November 2018

Interactions between electron and proton currents in excised patches from human eosinophils

1 reference

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2 November 2018

The requirement of cytosolic phospholipase A2 for the PMA activation of proton efflux through the N-terminal 230-amino-acid fragment of gp91phox

1 reference

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2 November 2018

Temperature dependence of NADPH oxidase in human eosinophils.

1 reference

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2 November 2018

The voltage dependence of NADPH oxidase reveals why phagocytes need proton channels

1 reference

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2 November 2018

Voltage-gated proton channels and other proton transfer pathways

1 reference

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2 November 2018

Participation of the arachidonic acid cascade pathway in macrophage binding/uptake of oxidized low density lipoprotein

1 reference

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2 November 2018

Characterization of a novel inhibitor of cytosolic phospholipase A2alpha, pyrrophenone

1 reference

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2 November 2018

Regulation of human eosinophil NADPH oxidase activity: a central role for PKCdelta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075394

2 November 2018

Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075394

2 November 2018

Interactions between NADPH oxidase-related proton and electron currents in human eosinophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075394

2 November 2018

The gp91phox component of NADPH oxidase is not the voltage-gated proton channel in phagocytes, but it helps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075394

2 November 2018

Protein kinases C translocation responses to low concentrations of arachidonic acid

1 reference

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2 November 2018

Activation and priming of neutrophil nicotinamide adenine dinucleotide phosphate oxidase and phospholipase A(2) are dissociated by inhibitors of the kinases p42(ERK2) and p38(SAPK) and by methyl arachidonyl fluorophosphonate, the dual inhibitor of c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075394

2 November 2018

Pyrrolidine inhibitors of human cytosolic phospholipase A2. Part 2: synthesis of potent and crystallized 4-triphenylmethylthio derivative 'pyrrophenone'.

1 reference

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2 November 2018

Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways

1 reference

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2 November 2018

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

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2 November 2018

Cytosolic phospholipase A2 is required for the activation of the NADPH oxidase associated H+ channel in phagocyte-like cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075394

2 November 2018

Simultaneous activation of NADPH oxidase-related proton and electron currents in human neutrophils.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075394

2 November 2018

Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase

1 reference

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2 November 2018

A novel H(+) conductance in eosinophils: unique characteristics and absence in chronic granulomatous disease

1 reference

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2 November 2018

Essential requirement of cytosolic phospholipase A(2) for activation of the H(+) channel in phagocyte-like cells

1 reference

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2 November 2018

NADPH oxidase: an update

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2 November 2018

Role of arachidonic acid and its metabolites in the priming of NADPH oxidase in human polymorphonuclear leukocytes by peritoneal dialysis effluent

1 reference

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2 November 2018

Stimulation of p38 phosphorylation and activity by arachidonic acid in HeLa cells, HL60 promyelocytic leukemic cells, and human neutrophils. Evidence for cell type-specific activation of mitogen-activated protein kinases.

1 reference

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2 November 2018

Electron currents generated by the human phagocyte NADPH oxidase.

1 reference

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2 November 2018

Essential requirement of cytosolic phospholipase A2 for activation of the phagocyte NADPH oxidase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075394

2 November 2018

Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2

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2 November 2018

Electrogenic H+ pathway contributes to stimulus-induced changes of internal pH and membrane potential in intact neutrophils: role of cytoplasmic phospholipase A2.

1 reference

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2 November 2018

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.

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2 November 2018

Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2.

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2 November 2018

The requirement for phospholipase A2 for activation of the assembled NADPH oxidase in human neutrophils

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2 November 2018

A pH-sensitive and voltage-dependent proton conductance in the plasma membrane of macrophages

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Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets.

1 reference

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2 November 2018

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

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Regulation of the electrogenic H+ channel in the plasma membrane of neutrophils: possible role of phospholipase A2, internal and external protons

1 reference

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Arachidonic acid stimulates the plasma membrane H+ conductance of macrophages.

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2 November 2018

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Direct activation of purified protein kinase C by unsaturated fatty acids (oleate and arachidonate) in the absence of phospholipids and Ca2+.

1 reference

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Release of arachidonate and reduction of oxygen. Independent metabolic bursts of the mouse peritoneal macrophage

1 reference

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Activation of NADPH-dependent superoxide production in a cell-free system by sodium dodecyl sulfate.

1 reference

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Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor

1 reference

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1 reference

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2 November 2018

Superoxide generation by the electrogenic NADPH oxidase of human neutrophils is limited by the movement of a compensating charge

1 reference

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2 November 2018

The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2075394

2 November 2018

Superoxide generation is inhibited by phospholipase A2 inhibitors. Role for phospholipase A2 in the activation of the NADPH oxidase

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2 November 2018

Continuous phosphorylation of both the 47 and the 49 kDa proteins occurs during superoxide production by neutrophils

1 reference

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2 November 2018

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

1 reference

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2 November 2018

Protein kinase C activates an H+ (equivalent) conductance in the plasma membrane of human neutrophils

1 reference

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2 November 2018

The NADPH-oxidase-associated H+ channel is opened by arachidonate

1 reference

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2 November 2018

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1 reference

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2 November 2018

Effects of antagonists of protein phosphatases on superoxide release by neutrophils

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Proton currents in human eosinophils

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Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17185330

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https://pubmed.ncbi.nlm.nih.gov/17185330

12 December 2020

based on heuristic

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https://pubmed.ncbi.nlm.nih.gov/17185330

12 December 2020

based on heuristic

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Activation of nadph-oxidase by arachidonic acid involves phospholipase A2 in intact human neutrophils but not in the cell-free system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17185330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of neutrophil activation by okadaic acid, a protein phosphatase inhibitor

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https://pubmed.ncbi.nlm.nih.gov/17185330

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/17185330

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based on heuristic

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Method for manipulation of cytosolic pH in cells clamped in the whole cell or perforated-patch configurations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17185330

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Neutrophil release of arachidonic acid, oxidants, and proteinases: causally related or independent

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Voltage-activated proton current in eosinophils from human blood

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Identifiers

10.1113/JPHYSIOL.2006.124248

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17185330%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17185330%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

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