Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase (Q36692807)

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scientific article published on 8 October 2004

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English	Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase	scientific article published on 8 October 2004

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scholarly article

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PMC publication ID

15 August 2017

Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase (English)

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15 August 2017

Michael Glogauer

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Michael Glogauer

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Gregory P. Downey

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Gregory P Downey

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Sergio Grinstein

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Sergio Grinstein

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Michael H. Gelb

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Michael H Gelb

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15 August 2017

author name string

Barry B Rubin

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15 August 2017

Adeline Koh

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Norbert Degousee

4

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15 August 2017

Farideh Ghomashchi

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15 August 2017

Laxman Nallan

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15 August 2017

Eva Stefanski

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15 August 2017

Denis W Harkin

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15 August 2017

Chunxiang Sun

9

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15 August 2017

Brian P Smart

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Thomas F Lindsay

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Vera Cherepanov

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Eric Vachon

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David Kelvin

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Martin Sadilek

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Glenn E Brown

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Michael B Yaffe

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Jonathan Plumb

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publication date

8 October 2004

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15 August 2017

Journal of Biological Chemistry

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15 August 2017

280

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15 August 2017

9

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15 August 2017

7519-7529

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Europe PubMed Central

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15 August 2017

Cytometric bead array: a multiplexed assay platform with applications in various areas of biology

1 reference

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30 September 2017

Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A(2) occurs predominantly during the secretory process and with the involvement of cytosolic phospholipase A(2)-alpha

1 reference

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Neutrophil extracellular traps kill bacteria

1 reference

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Deaths: preliminary data for 2002.

1 reference

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30 September 2017

Phagocytosis by neutrophils

1 reference

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

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30 September 2017

Unique targeting of cytosolic phospholipase A2 to plasma membranes mediated by the NADPH oxidase in phagocytes

1 reference

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Expression profiling reveals off-target gene regulation by RNAi

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An Essential Role of Cytosolic Phospholipase A2α in Prostaglandin E2–mediated Bone Resorption Associated with Inflammation

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30 September 2017

Cytosolic Phospholipase A2α–deficient Mice Are Resistant to Collagen-induced Arthritis

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Atypical protein kinase C-zeta is essential for delayed phagocytosis of Helicobacter pylori

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Regulation of platelet-activating factor synthesis in human neutrophils by MAP kinases

1 reference

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Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis

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A pyrrolidine-based specific inhibitor of cytosolic phospholipase A(2)alpha blocks arachidonic acid release in a variety of mammalian cells

1 reference

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Enhanced susceptibility to pulmonary infection with Burkholderia cepacia in Cftr(-/-) mice

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Innate immunity and pulmonary host defense

1 reference

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Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G

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Cytosolic phospholipase A2 is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cells

1 reference

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The lung in the immunocompromised patient. Infectious complications Part 1.

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5-Lipoxygenase reaction products modulate alveolar macrophage phagocytosis of Klebsiella pneumoniae

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Role of arachidonic acid and its metabolites in the priming of NADPH oxidase in human polymorphonuclear leukocytes by peritoneal dialysis effluent

1 reference

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30 September 2017

Essential requirement of cytosolic phospholipase A2 for activation of the phagocyte NADPH oxidase.

1 reference

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30 September 2017

Properties and regulation of cytosolic phospholipase A2.

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The C5a chemoattractant receptor mediates mucosal defence to infection

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Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer

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Platelet-activating factor: the biosynthetic and catabolic enzymes

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Flow cytometric analysis of the granulocyte respiratory burst: a comparison study of fluorescent probes.

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Platelet-activating factor mediates acid-induced lung injury in genetically engineered mice

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Arachidonic acid acts as an intracellular activator of NADPH-oxidase in Fc gamma receptor-mediated superoxide generation in macrophages.

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Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2

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Cytosolic phospholipase A2 translocates to forming phagosomes during phagocytosis of zymosan in macrophages

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Regulation and kinetics of platelet-activating factor and leukotriene C4 synthesis by activated human basophils.

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Structural changes are induced in human neutrophil cytochrome b by NADPH oxidase activators, LDS, SDS, and arachidonate: intermolecular resonance energy transfer between trisulfopyrenyl-wheat germ agglutinin and cytochrome b(558).

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1 reference

https://pubmed.ncbi.nlm.nih.gov/15475363

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The final step in the de novo biosynthesis of platelet-activating factor. Properties of a unique CDP-choline:1-alkyl-2-acetyl-sn-glycerol choline-phosphotransferase in microsomes from the renal inner medulla of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475363

12 December 2020

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Tight binding inhibitors of 85-kDa phospholipase A2 but not 14-kDa phospholipase A2 inhibit release of free arachidonate in thrombin-stimulated human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475363

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Potentiation of the oxidative burst of human neutrophils. A signaling role for L-selectin

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https://pubmed.ncbi.nlm.nih.gov/15475363

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Neutrophil release of arachidonic acid, oxidants, and proteinases: causally related or independent

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475363

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based on heuristic

inferred from PubMed ID database lookup

PLA2 promotes fusion between PMN-specific granules and complex liposomes

1 reference

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inferred from PubMed ID database lookup

Platelet-activating Factor Plays a Pivotal Role in the Induction of Experimental Lung Injury

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/15475363

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inferred from PubMed ID database lookup

Involvement of cytosolic phospholipase A2 and secretory phospholipase A2 in arachidonic acid release from human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475363

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based on heuristic

inferred from PubMed ID database lookup

Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation

1 reference

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1 reference

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based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/15475363

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based on heuristic

inferred from PubMed ID database lookup

Priming of the neutrophil respiratory burst is species-dependent and involves MAP kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15475363

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M407438200

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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