Regenerative medicine and cell-based approaches to restore pancreatic function. (Q52543005)

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Gene and cell-replacement therapy in the treatment of type 1 diabetes: how high must the standards be set?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Closing in on Mass Production of Mature Human Beta Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

The quest to make fully functional human pancreatic beta cells from embryonic stem cells: climbing a mountain in the clouds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Under Utilization of Pancreas Transplants in Cystic Fibrosis Recipients in the United Network Organ Sharing (UNOS) Data 1987-2014.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Effect of mesenchymal stem cells on renal injury in rats with severe acute pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Role of bone marrow-derived mesenchymal stem cells in a rat model of severe acute pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Protective effects of transplanted and mobilized bone marrow stem cells on mice with severe acute pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Effect of umbilical cord mesenchymal stem cells on treatment of severe acute pancreatitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Regeneration and repair of the exocrine pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pancreatic ductal adenocarcinoma cell lines display a plastic ability to bi‑directionally convert into cancer stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Centroacinar cells: At the center of pancreas regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Stem cells versus plasticity in liver and pancreas regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Partial pancreatectomy in adult humans does not provoke beta-cell regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pancreatic regeneration after near-total pancreatectomy in children with nesidioblastosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Models of pancreatic regeneration in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Centroacinar Cells Are Progenitors That Contribute to Endocrine Pancreas Regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pten constrains centroacinar cell expansion and malignant transformation in the pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Partial duct ligation: β-cell proliferation and beyond.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Neurogenin 3+ cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Gene delivery to pancreatic exocrine cells in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Clinical pancreatic islet transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Islet transplant: an option for childhood diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Isolated human islets trigger an instant blood mediated inflammatory reaction: implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Justifying clinical trials for porcine islet xenotransplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Clinical islet xenotransplantation: how close are we?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Islet cell xenotransplantation: a serious look toward the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

New life for pig-to-human transplants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Genome-wide inactivation of porcine endogenous retroviruses (PERVs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Creating class I MHC-null pigs using guide RNA and the Cas9 endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Targeted disruption of the alpha1,3-galactosyltransferase gene in cloned pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Growing human organs in pigs-A dream or reality?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Interspecies organogenesis generates autologous functional islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Glucose-induced toxicity in insulin-producing pituitary cells that coexpress GLUT2 and glucokinase. Implications for metabolic engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

β-cell-mimetic designer cells provide closed-loop glycemic control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Development of a conditionally immortalized human pancreatic β cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Glucose-sensing mechanisms in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Blood glucose normalization upon transplantation of human embryonic pancreas into beta-cell-deficient SCID mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Fetal pancreas transplantation for treatment of IDDM patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Maturation and function of human embryonic stem cell-derived pancreatic progenitors in macroencapsulation devices following transplant into mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Differentiation of human pluripotent stem cells into β-cells: Potential and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Generation of functional human pancreatic β cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Human pancreatic beta-like cells converted from fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Immunogenicity of human embryonic stem cell-derived beta cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

HLA engineering of human pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

A future with less HLA: potential clinical applications of HLA-universal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Revascularization of transplanted pancreatic islets and role of the transplantation site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Advances in pancreatic islet transplantation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Transaminitis after pancreatic islet transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Prevalence of hepatic steatosis after islet transplantation and its relation to graft function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Bioengineered sites for islet cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

A novel technique for the transplantation of pancreatic islets within a vascularized device into the greater omentum to achieve insulin independence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Survival and metabolic function of syngeneic rat islet grafts transplanted in the omental pouch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Bioengineering the Endocrine Pancreas: Intraomental Islet Transplantation Within a Biologic Resorbable Scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pancreatic islets find a new transplant home in the omentum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Evaluation of alternative sites for islet transplantation in the minipig: interest and limits of the gastric submucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Endoscopic gastric submucosal transplantation of islets (ENDO-STI): technique and initial results in diabetic pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Extracellular Matrix and Growth Factors Improve the Efficacy of Intramuscular Islet Transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Clinical and experimental pancreatic islet transplantation to striated muscle: establishment of a vascular system similar to that in native islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Islet survival and function following intramuscular autotransplantation in the minipig

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Total pancreatectomy with and without islet cell transplantation for chronic pancreatitis: a series of 85 consecutive patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Islet auto transplantation following total pancreatectomy: a long-term assessment of graft function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Bone marrow as an alternative site for islet transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Autologous pancreatic islet transplantation in human bone marrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Extracellular matrix in pancreatic islets: relevance to scaffold design and transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Self-assembling peptide nanofiber as potential substrates in islet transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Matrix components and scaffolds for sustained islet function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Cooperative signaling for angiogenesis and neovascularization by VEGF and HGF following islet transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

The Efficacy of a Prevascularized, Retrievable Poly(D,L,-lactide-co-ε-caprolactone) Subcutaneous Scaffold as Transplantation Site for Pancreatic Islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

A prevascularized subcutaneous device-less site for islet and cellular transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Islets transplanted in immunoisolation devices: a review of the progress and the challenges that remain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Insulin-Producing Endocrine Cells Differentiated In Vitro From Human Embryonic Stem Cells Function in Macroencapsulation Devices In Vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Composition and function of macroencapsulated human embryonic stem cell-derived implants: comparison with clinical human islet cell grafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Technology of mammalian cell encapsulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Noninvasive evaluation of the vascular response to transplantation of alginate encapsulated islets using the dorsal skin-fold model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Alginate encapsulant incorporating CXCL12 supports long-term allo- and xenoislet transplantation without systemic immune suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Long-term metabolic and immunological follow-up of nonimmunosuppressed patients with type 1 diabetes treated with microencapsulated islet allografts: four cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Safety and viability of microencapsulated human islets transplanted into diabetic humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Reversal of type 1 diabetes by engineering a glucose sensor in skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Insulin-secreting non-islet cells are resistant to autoimmune destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

In vitro cultivation of human islets from expanded ductal tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Reprogramming Mouse Cells With a Pancreatic Duct Phenotype to Insulin-Producing β-Like Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Inhibition of Hes1 activity in gall bladder epithelial cells promotes insulin expression and glucose responsiveness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Mitogenic effect of gastrin and expression of gastrin receptors in duct-like cells of rat pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57Bl6/J mice treated with alloxan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Hyperglycaemia attenuates in vivo reprogramming of pancreatic exocrine cells to beta cells in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pancreatic Inflammation Redirects Acinar to β Cell Reprogramming.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Generation of Functional Beta-Like Cells from Human Exocrine Pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Suppression of epithelial-to-mesenchymal transitioning enhances ex vivo reprogramming of human exocrine pancreatic tissue toward functional insulin-producing β-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pdx1 expression in pancreatic precursor lesions and neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

β-cell mass and turnover in humans: effects of obesity and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Human pancreatic β-cell G1/S molecule cell cycle atlas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Serotonin regulates pancreatic beta cell mass during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Expansion of beta-cell mass in response to pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Inhibition of DYRK1A Stimulates Human β-Cell Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

SerpinB1 Promotes Pancreatic β Cell Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Diabetes mellitus--advances and challenges in human β-cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Insulin-positive, Glut2-low cells present within mouse pancreas exhibit lineage plasticity and are enriched within extra-islet endocrine cell clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Identification of proliferative and mature β-cells in the islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Opposing actions of Arx and Pax4 in endocrine pancreas development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Getting your Pax straight: Pax proteins in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Functional, persistent, and extended liver to pancreas transdifferentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

In vivo reprogramming of Sox9+ cells in the liver to insulin-secreting ducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Stable insulin-secreting ducts formed by reprogramming of cells in the liver using a three-gene cocktail and a PPAR agonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Generation of insulin-producing cells from the mouse liver using β cell-related gene transfer including Mafa and Mafb

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Generation of functional insulin-producing cells from neonatal porcine liver-derived cells by PDX1/VP16, BETA2/NeuroD and MafA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Gene therapy with neurogenin3, betacellulin and SOCS1 reverses diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Inducible apoptosis as a safety switch for adoptive cell therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Gene therapy for diabetes mellitus in rats by hepatic expression of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Long-term correction of diabetes in rats after lentiviral hepatic insulin gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Diabetes therapy by lentiviral hepatic insulin gene expression without transformation of liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Reversal of diabetes through gene therapy of diabetic rats by hepatic insulin expression via lentiviral transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Glucose- and metabolically regulated hepatic insulin gene therapy for diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Long-term glycemic control with hepatic insulin gene therapy in streptozotocin-diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Hepatic insulin gene therapy prevents deterioration of vascular function and improves adipocytokine profile in STZ-diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Hepatic insulin gene therapy prevents diabetic enteropathy in STZ-treated CD-1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Transplantation of reversibly immortalized insulin-secreting human hepatocytes controls diabetes in pancreatectomized pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Glucose-Responsive Hepatic Insulin Gene Therapy of Spontaneously Diabetic BB/Wor Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Regulated hepatic insulin gene therapy of STZ-diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Control of endodermal endocrine development by Hes-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Minireview: Development and differentiation of gut endocrine cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Harnessing the gut to treat diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Regulation of pancreatic juxtaductal endocrine cell formation by FoxO1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Generation of functional insulin-producing cells in the gut by Foxo1 ablation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

De novo formation of insulin-producing "neo-β cell islets" from intestinal crypts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

The promise and potential hazards of adenovirus gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Multi-compartmental oral delivery systems for nucleic acid therapy in the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Gene delivery in salivary glands: from the bench to the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

The endocrine secretion of human insulin and growth hormone by exocrine glands of the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Expression and secretion of human proinsulin-B10 from mouse salivary glands: implications for the treatment of type I diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Advances in salivary gland gene therapy - oral and systemic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Glucose-dependent insulin release from genetically engineered K cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Outpatient glycemic control with a bionic pancreas in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

A multi-year analysis of islet transplantation compared with intensive medical therapy on progression of complications in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

The prevalence of comorbid depression in adults with diabetes: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Economic costs of diabetes in the U.S. in 2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Impact of Socioeconomic Status on Cardiovascular Disease and Mortality in 24,947 Individuals With Type 1 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

The genetic architecture of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Metaplasia in the pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

21 January 2018

Cancer statistics, 2010

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Burden of gastrointestinal disease in the United States: 2012 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Frequency of progression from acute to chronic pancreatitis and risk factors: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Chronic pancreatitis, pseudotumors and other tumor-like lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Exome Sequencing Deciphers Rare Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Insulin-Producing Intestinal K Cells Protect Nonobese Diabetic Mice From Autoimmune Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Human bone marrow-derived clonal mesenchymal stem cells inhibit inflammation and reduce acute pancreatitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Adenovirus-mediated transfer of human lipase complementary DNA to the gallbladder.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Adenovirus-mediated human pancreatic lipase gene transfer to rat bile: gene therapy of fat malabsorption

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Islet cell damage associated with tacrolimus and cyclosporine: morphological features in pancreas allograft biopsies and clinical correlation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Recovery of human fetal pancreas after one year of implantation in the diabetic patient

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Japanese man is first to receive 'reprogrammed' stem cells from another person

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Prevention of bleeding after islet transplantation: lessons learned from a multivariate analysis of 132 cases at a single institution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Magnetic resonance-defined periportal steatosis following intraportal islet transplantation: a functional footprint of islet graft survival?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Intramuscular islet transplantation promotes restored islet vascularity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Intramuscular autotransplantation of pancreatic islets in a 7-year-old child: a 2-year follow-up

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Acute Ischemia Induced by High Density Culture Increases Cytokine Expression and Diminishes the Function and Viability of Highly Purified Human Islets of Langerhans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Sustained function of alginate-encapsulated human islet cell implants in the peritoneal cavity of mice leading to a pilot study in a type 1 diabetic patient

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Six-month survival of microencapsulated pig islets and alginate biocompatibility in primates: proof of concept

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Human pancreatic ductal cells: large-scale isolation and expansion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Cell populations in the endocrine pancreas of human neonates and infants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Diabetes enhances the proliferation of adult pancreatic multipotent progenitor cells and biases their differentiation to more β-cell production

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2017.93

Maturity-onset diabetes of the young (MODY): an update

31 March 2020

1 reference

12 December 2020

A morphological study of the endocrine pancreas in human pregnancy

1 reference

12 December 2020

Genetically reprogrammed, liver-derived insulin-producing cells are glucose-responsive, but susceptible to autoimmune destruction in settings of murine model of type 1 diabetes

1 reference

12 December 2020

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

1 reference

12 December 2020

Restoration of exocrine pancreatic function following pancreas-liver-kidney transplantation in a cystic fibrosis patient

1 reference

12 December 2020

Clinical transplantation of fetal human pancreatic islets

1 reference

12 December 2020

Addiction: Part I. Benzodiazepines--side effects, abuse risk and alternatives.

1 reference

12 December 2020

Review of current and emerging therapies in type 2 diabetes mellitus.

1 reference

12 December 2020

Islet cell transplantation for the treatment of type 1 diabetes: recent advances and future challenges

1 reference

12 December 2020

Pancreas regeneration after resection: does it occur in humans?

1 reference

12 December 2020

Pancreaticoduodenal transplantation with enteric drainage following native total pancreatectomy for chronic pancreatitis: a case report

1 reference

12 December 2020

Genetically engineered proinsulin constitutively processed and secreted as mature, active insulin

1 reference

12 December 2020

Developmental biology of the pancreas

1 reference

12 December 2020

Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye.

1 reference

12 December 2020

Role of bone marrow mesenchymal stem cells in L-arg-induced acute pancreatitis: effects and possible mechanisms.

1 reference

12 December 2020

The endocrine secretion of mammalian digestive enzymes by exocrine glands

1 reference

12 December 2020

Effects of hepatic insulin gene therapy on enteric neuropathy in STZ-diabetic mice

1 reference

12 December 2020

Abuse Potential of Soma: the GABA(A) Receptor as a Target

1 reference

12 December 2020

Enzyme replacement therapy for pancreatic insufficiency: present and future

1 reference

12 December 2020

Economic 3D-printing approach for transplantation of human stem cell-derived β-like cells

1 reference

12 December 2020

Pancreatic and duodenal homeobox gene 1 (Pdx1) down-regulates hepatic transcription factor 1 alpha (HNF1α) expression during reprogramming of human hepatic cells into insulin-producing cells

1 reference

12 December 2020

Proceedings: the survival of transplanted isolated pancreatic islets in the omentum and testis

1 reference

12 December 2020