PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis (Q51298888)

3 April 2018

https://doi.org/10.1158/0008-5472.CAN-24-2215

1 reference

20 September 2024

https://retractionwatch.com/?s=%22Gregg+Semenza%22

title

PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis (English)

1 reference

3 April 2018

main subject

neoplastic stem cells

1 reference

Gregg L Semenza

1 reference

3 April 2018

Laura M Shelton

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3 April 2018

author name string

Debangshu Samanta

1 reference

3 April 2018

Youngrok Park

1 reference

3 April 2018

Shaida A Andrabi

1 reference

3 April 2018

Daniele M Gilkes

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3 April 2018

language of work or name

English

0 references

publication date

8 June 2016

1 reference

3 April 2018

published in

Cancer Research

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3 April 2018

volume

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3 April 2018

issue

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3 April 2018

page(s)

4430-4442

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3 April 2018

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

cites work

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/J.CCR.2006.10.008

cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Quantitative Metabolome Analysis Using Capillary Electrophoresis Mass Spectrometry

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Introduction to tumor microenvironment regulation of cancer cell survival, metastasis, inflammation, and immune surveillance

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Hypoxia--a key regulatory factor in tumour growth

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Serine catabolism regulates mitochondrial redox control during hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Metastatic stem cells: sources, niches, and vital pathways

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

The UCSC Cancer Genomics Browser: update 2013.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Tumor cells upregulate normoxic HIF-1α in response to doxorubicin

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Superoxide scavenging by Mn(II/III) tetrakis (1-methyl-4-pyridyl) porphyrin in mammalian cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Prospective identification of tumorigenic breast cancer cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Cisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Comprehensive molecular portraits of human breast tumours

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Carboplatin in combination therapy for metastatic breast cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Pretreatment with dexamethasone increases antitumor activity of carboplatin and gemcitabine in mice bearing human cancer xenografts: in vivo activity, pharmacokinetics, and clinical implications for cancer chemotherapy

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Hypoxia-driven selection of the metastatic phenotype

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

GOBO: gene expression-based outcome for breast cancer online

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Reactive oxygen species in cancer: a dance with the devil

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast Cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

NRF2 regulates serine biosynthesis in non-small cell lung cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Metabolic regulation of hematopoietic stem cells in the hypoxic niche

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1158/0008-5472.CAN-16-0530

Identifiers

DOI

10.1158/0008-5472.CAN-16-0530

1 reference

3 April 2018

release_u37z756gunbermphfpizf7r52y

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/u37z756gunbermphfpizf7r52y

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

3 April 2018