cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions. (Q35291859)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793315%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions (English)

1 reference

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3 March 2020

1 reference

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3 March 2020

1 reference

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3 March 2020

1 reference

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3 March 2020

Libing Song

1 reference

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3 March 2020

Qianfen Wan

1 reference

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3 March 2020

Gongwei Wu

1 reference

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3 March 2020

Xinghua Li

1 reference

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3 March 2020

Yinghui Wang

1 reference

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3 March 2020

Jin Wang

1 reference

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3 March 2020

Zhaoji Liu

1 reference

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3 March 2020

Xiuying Zhong

1 reference

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3 March 2020

Xiaoping He

1 reference

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3 March 2020

Shengqi Shen

1 reference

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3 March 2020

Ailing Li

1 reference

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3 March 2020

Yulan Wang

1 reference

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3 March 2020

Ping Gao

1 reference

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3 March 2020

Huafeng Zhang

1 reference

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3 March 2020

publication date

20 March 2015

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3 March 2020

1 reference

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3 March 2020

volume

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3 March 2020

issue

1 reference

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3 March 2020

page(s)

429-444

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Serine catabolism regulates mitochondrial redox control during hypoxia

3 March 2020

cites work

1 reference

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Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis.

12 July 2018

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Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.

12 July 2018

1 reference

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Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis.

12 July 2018

1 reference

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Quantitative flux analysis reveals folate-dependent NADPH production.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Serine and glycine metabolism in cancer

12 July 2018

1 reference

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The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation

12 July 2018

1 reference

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p73 regulates serine biosynthesis in cancer.

12 July 2018

1 reference

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Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells

12 July 2018

1 reference

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MYC, metabolism, cell growth, and tumorigenesis.

12 July 2018

1 reference

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Serine, glycine and one-carbon units: cancer metabolism in full circle

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

TAp73 enhances the pentose phosphate pathway and supports cell proliferation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

MACC1 as a prognostic biomarker for early-stage and AFP-normal hepatocellular carcinoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

The Hunger Games: p53 regulates metabolism upon serine starvation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis

12 July 2018

1 reference

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Cancer metabolism: key players in metabolic reprogramming

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Overexpression of the mitochondrial folate and glycine-serine pathway: a new determinant of methotrexate selectivity in tumors

12 July 2018

1 reference

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c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Transcriptional amplification in tumor cells with elevated c-Myc.

12 July 2018

1 reference

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Upregulator of cell proliferation predicts poor prognosis in hepatocellular carcinoma and contributes to hepatocarcinogenesis by downregulating FOXO3a

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Resurgence of serine: an often neglected but indispensable amino Acid

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

MYC on the path to cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Serine hydroxymethyltransferase anchors de novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Glutamine: pleiotropic roles in tumor growth and stress resistance

12 July 2018

1 reference

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Regulation of cancer cell metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

MYC as a regulator of ribosome biogenesis and protein synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Reactive oxygen species, cellular redox systems, and apoptosis

12 July 2018

1 reference

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L-serine synthesis in the central nervous system: a review on serine deficiency disorders

12 July 2018

1 reference

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The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics

12 July 2018

1 reference

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Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Global regulation of nucleotide biosynthetic genes by c-Myc

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Glucose metabolism and cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

On the Origin of Cancer Cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

The importance of glutathione in human disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

L-serine in disease and development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Glutamine, as a precursor of glutathione, and oxidative stress

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

The reactions of the phosphorylated pathway of L-serine biosynthesis: thermodynamic relationships in rabbit liver in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Gene regulation: fine-tuned amplification in cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Glutaminolysis: Supplying carbon or nitrogen or both for cancer cells?

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4387561

Glutathione: an overview of biosynthesis and modulation

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25793315

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CR.2015.33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793315%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793315%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

25793315

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793315%20AND%20SRC:MED&resulttype=core&format=json