Molecular Mechanism of Substrate Processing by the Cdc48 ATPase Complex (Q51018275)

19 June 2018

title

Molecular Mechanism of Substrate Processing by the Cdc48 ATPase Complex (English)

1 reference

19 June 2018

Tom A Rapoport

1 reference

19 June 2018

author name string

Nicholas O Bodnar

series ordinal

1 reference

19 June 2018

language of work or name

English

0 references

publication date

1 May 2017

1 reference

19 June 2018

published in

Cell

1 reference

19 June 2018

volume

169

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19 June 2018

issue

1 reference

19 June 2018

page(s)

722-735.e9

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19 June 2018

Unfolding the mechanism of the AAA+ unfoldase VAT by a combined cryo-EM, solution NMR study

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22 June 2018

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22 June 2018

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22 June 2018

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Key steps in ERAD of luminal ER proteins reconstituted with purified components

22 June 2018

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22 June 2018

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Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains

22 June 2018

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22 June 2018

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Cleaning up in the endoplasmic reticulum: ubiquitin in charge

22 June 2018

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Roles of Cdc48 in regulated protein degradation in yeast.

22 June 2018

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22 June 2018

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Bipartite determinants mediate an evolutionarily conserved interaction between Cdc48 and the 20S peptidase

22 June 2018

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Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome

22 June 2018

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Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

22 June 2018

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Identification of the Cdc48•20S proteasome as an ancient AAA+ proteolytic machine.

22 June 2018

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Roles of p97-associated deubiquitinases in protein quality control at the endoplasmic reticulum

22 June 2018

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Rational design of true monomeric and bright photoactivatable fluorescent proteins

22 June 2018

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22 June 2018

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Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97.

22 June 2018

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Mitochondrial quality control by the ubiquitin-proteasome system

22 June 2018

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The Cdc48 ATPase modulates the interaction between two proteolytic factors Ufd2 and Rad23.

22 June 2018

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AAA+ Proteases: ATP-Fueled Machines of Protein Destruction

22 June 2018

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The complexities of p97 function in health and disease

22 June 2018

1 reference

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Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.

22 June 2018

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Degradation of ubiquitin: the fate of the cellular reaper

22 June 2018

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The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER

22 June 2018

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A conserved unfoldase activity for the p97 AAA-ATPase in proteasomal degradation

22 June 2018

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Both ATPase domains of ClpA are critical for processing of stable protein structures

22 June 2018

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VCP disease associated with myopathy, Paget disease of bone and frontotemporal dementia: review of a unique disorder

22 June 2018

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AAA+ ATPases: achieving diversity of function with conserved machinery

22 June 2018

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22 June 2018

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Central pore residues mediate the p97/VCP activity required for ERAD

22 June 2018

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Evolutionary relationships and structural mechanisms of AAA+ proteins

22 June 2018

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Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone

22 June 2018

1 reference

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Cellular functions, mechanism of action, and regulation of FtsH protease

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

Nucleotide dependent motion and mechanism of action of p97/VCP

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

A genomic screen identifies Dsk2p and Rad23p as essential components of ER-associated degradation

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

Multiple interactions of rad23 suggest a mechanism for ubiquitylated substrate delivery important in proteolysis

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

An expanded eukaryotic genetic code

22 June 2018

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Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

Addition of a photocrosslinking amino acid to the genetic code of Escherichiacoli

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

Effects of protein stability and structure on substrate processing by the ClpXP unfolding and degradation machine

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

Kinetics of unfolding and folding from amide hydrogen exchange in native ubiquitin

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

Recognition of the polyubiquitin proteolytic signal

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

Benzophenone photophores in biochemistry.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

The recognition component of the N-end rule pathway

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

A new set of highly efficient, tag-cleaving proteases for purifying recombinant proteins

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

An unstructured initiation site is required for efficient proteasome-mediated degradation

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5751438

Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28475898

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28475898

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2017.04.020

1 reference

19 June 2018

PMC publication ID

5751438

1 reference

19 June 2018

PubMed publication ID

28475898

1 reference

19 June 2018