Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility (Q58197500)

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Birgit Luber

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Ulrike Reich

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Christina Schott

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Sandra Oswald

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Helma Becke

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Peter Hutzler

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Walter Birchmeier

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Heinz Höfler

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Karl-Friedrich Becker

EndoCAM: a novel endothelial cell-cell adhesion molecule

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language of work or name

English

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publication date

July 1999

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4301-4312

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cites work

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Exon skipping in the E-cadherin gene transcript in metastatic human gastric carcinomas

21 January 2018

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Functional interaction of beta-catenin with the transcription factor LEF-1

21 January 2018

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Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

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Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1).

21 January 2018

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Rearrangements of desmosomal and cytoskeletal proteins during the transition from epithelial to fibroblastoid organization in cultured rat bladder carcinoma cells

21 January 2018

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The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

21 January 2018

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Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization

21 January 2018

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In vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cells

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Linear organization of the liver cell adhesion molecule L-CAM.

21 January 2018

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E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells

21 January 2018

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Disruption of epithelial cell-cell adhesion by exogenous expression of a mutated nonfunctional N-cadherin

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E-cadherin germline mutations in familial gastric cancer.

21 January 2018

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Rho GTPases and the actin cytoskeleton

21 January 2018

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A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis

21 January 2018

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An overview of epithelio-mesenchymal transformation

21 January 2018

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Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

21 January 2018

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Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

21 January 2018

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E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

21 January 2018

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

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Point mutation of the E-cadherin gene in invasive lobular carcinoma of the breast.

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From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

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Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin

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Cell migration: a physically integrated molecular process

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Role of morphogenetic factors in metastasis of mammary carcinoma cells.

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Actin-based cell motility and cell locomotion

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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E-cadherin gene mutations in signet ring cell carcinoma of the stomach

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The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules

21 January 2018

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Structural basis of calcium-induced E-cadherin rigidification and dimerization

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Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells.

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A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis

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Frequent loss of alpha catenin expression in scirrhous carcinomas with scattered cell growth.

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E-cadherin gene mutations in human gastric carcinoma cell lines

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Solution structure of the epithelial cadherin domain responsible for selective cell adhesion.

21 January 2018

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Single amino acid substitutions in one Ca2+ binding site of uvomorulin abolish the adhesive function

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Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule

21 January 2018

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Correct proteolytic cleavage is required for the cell adhesive function of uvomorulin

21 January 2018

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Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex

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Mutations of the E-cadherin gene in human gynecologic cancers

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Association of the APC gene product with beta-catenin

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Simultaneous expression of cadherin-11 in signet-ring cell carcinoma and stromal cells of diffuse-type gastric cancer

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Association of the APC tumor suppressor protein with catenins

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Molecular mechanism of stomach carcinogenesis.

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Cadherin cell adhesion receptors as a morphogenetic regulator

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Cadherins in cancer: implications for invasion and metastasis

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Inactivation of the E-cadherin gene in primary gastric carcinomas and gastric carcinoma cell lines

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Remodeling the cell surface distribution of membrane proteins during the development of epithelial cell polarity

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Signal transduction and actin filament organization

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Lateral self-assembly of E-cadherin directed by cooperative calcium binding

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Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA

21 January 2018

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The role of E-cadherin and scatter factor in tumor invasion and cell motility

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7 January 2021

Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness

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7 January 2021

Prognostic value of E-cadherin expression in 413 gastric carcinomas

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7 January 2021

Cell adhesion molecules as tumour suppressors

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7 January 2021

Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain

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7 January 2021

The two histological main types of gastric carcinoma: diffuse and so called intestinal-type carcinoma: an attempt at a histo-clinical classification

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7 January 2021

Immunohistochemical evaluation of alpha-catenin expression in human gastric cancer

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7 January 2021

In Situ Embedding of Cell Monolayers Cultured on Plastic Surfaces for Electron Microscopy

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7 January 2021

Expressed recombinant cadherins mediate cell sorting in model systems

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7 January 2021

Loss of membranous E-cadherin expression in pancreatic cancer: correlation with lymph node metastasis, high grade, and advanced stage

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7 January 2021

Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding

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7 January 2021

Clinicopathologic evaluation of immunohistochemical E-cadherin expression in human gastric carcinomas

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7 January 2021