Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials (Q58119417)

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scientific article published on 23 October 2018

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English	Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials	scientific article published on 23 October 2018

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scholarly article

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30 April 2020

Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials (English)

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30 April 2020

phase III clinical trial

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based on heuristic

inferred from title

phenylketonuria

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author name string

Soumi Gupta

1

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30 April 2020

Kelly Lau

2

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30 April 2020

Cary O Harding

3

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30 April 2020

Gillian Shepherd

4

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30 April 2020

Ryan Boyer

5

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30 April 2020

John P Atkinson

6

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30 April 2020

Vijaya Knight

7

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30 April 2020

Joy Olbertz

8

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30 April 2020

Kevin Larimore

9

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30 April 2020

Zhonghu Gu

10

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30 April 2020

Mingjin Li

11

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30 April 2020

Orli Rosen

12

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30 April 2020

Stephen J Zoog

13

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30 April 2020

Haoling H Weng

14

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30 April 2020

Becky Schweighardt

15

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30 April 2020

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publication date

23 October 2018

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30 April 2020

1 reference

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30 April 2020

37

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30 April 2020

366-373

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30 April 2020

Enzyme therapy in Gaucher disease type 1: effect of neutralizing antibodies to acid beta-glucosidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenylketonuria in adulthood: a collaborative study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical features and severity grading of anaphylaxis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

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Second symposium on the definition and management of anaphylaxis: summary report--second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

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Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

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Structural and Biochemical Characterization of the Therapeutic Anabaena variabilis Phenylalanine Ammonia Lyase

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quality of life in noncompliant adults with phenylketonuria after resumption of the diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suboptimal outcomes in patients with PKU treated early with diet alone: Revisiting the evidence

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenicity to therapeutic proteins: impact on PK/PD and efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenicity and PK/PD evaluation in biotherapeutic drug development: scientific considerations for bioanalytical methods and data analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenylalanine hydroxylase deficiency: diagnosis and management guideline

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Questioning the Use of PEGylation for Drug Delivery.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential induction of anti-PEG antibodies and complement activation toward PEGylated therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative therapies to address the unmet medical needs of patients with phenylketonuria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-PEG immunity: emergence, characteristics, and unaddressed questions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenicity to Biotherapeutics - The Role of Anti-drug Immune Complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenylketonuria (PKU): A problem solved?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Mystery of Antibodies Against Polyethylene Glycol (PEG) - What do we Know?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adherence to clinic recommendations among patients with phenylketonuria in the United States

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropsychiatric comorbidities in adults with phenylketonuria: A retrospective cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pegvaliase for the treatment of phenylketonuria: Results of a long-term phase 3 clinical trial program (PRISM).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30366815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EBIOM.2018.10.038

1 reference

Europe PubMed Central

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30 April 2020

PMC publication ID

1 reference

Europe PubMed Central

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30 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30366815%20AND%20SRC:MED&resulttype=core&format=json

30 April 2020

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