Successful treatment of disseminated intravascular coagulation by recombinant human soluble thrombomodulin in patients with acute myeloid leukemia (Q58083422)

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scientific article published on 01 November 2018

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English	Successful treatment of disseminated intravascular coagulation by recombinant human soluble thrombomodulin in patients with acute myeloid leukemia	scientific article published on 01 November 2018

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scholarly article

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1 May 2020

Successful treatment of disseminated intravascular coagulation by recombinant human soluble thrombomodulin in patients with acute myeloid leukemia (English)

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1 May 2020

disseminated intravascular coagulation

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acute myeloid leukemia

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Miyuki Ookura

1

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1 May 2020

Naoko Hosono

2

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1 May 2020

Toshiki Tasaki

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1 May 2020

Kana Oiwa

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1 May 2020

Kei Fujita

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1 May 2020

Kazuhiro Ito

6

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1 May 2020

Shin Lee

7

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1 May 2020

Yasufumi Matsuda

8

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1 May 2020

Mihoko Morita

9

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1 May 2020

Katsunori Tai

10

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1 May 2020

Eiju Negoro

11

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1 May 2020

Shinji Kishi

12

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1 May 2020

Hiromichi Iwasaki

13

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1 May 2020

Takanori Ueda

14

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1 May 2020

Takahiro Yamauchi

15

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1 May 2020

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publication date

1 November 2018

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1 May 2020

Medicine (Barcelona) / Programa de Educación Médica Continuada (EMC) en medicina Asistencial

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1 May 2020

97

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1 May 2020

44

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1 May 2020

e12981

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1 May 2020

15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The "Retinoic Acid Syndrome" in Acute Promyelocytic Leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The last three consecutive epidermal growth factor-like structures of human thrombomodulin comprise the minimum functional domain for protein C-activating cofactor activity and anticoagulant activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene structure of human thrombomodulin, a cofactor for thrombin-catalyzed activation of protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Criteria for diagnosis of DIC based on the analysis of clinical and laboratory findings in 345 DIC patients collected by the Research Committee on DIC in Japan

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombomodulin structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of all-trans-retinoic acid on the coagulopathy of acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffuse alveolar hemorrhage with underlying pulmonary capillaritis in the retinoic acid syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Annexin II and bleeding in acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disseminated intravascular coagulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant thrombomodulin and activated protein C in the treatment of disseminated intravascular coagulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is protease inhibitor a choice for the treatment of pre- or mild disseminated intravascular coagulation?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disseminated intravascular coagulation current concepts of etiology, pathophysiology, diagnosis, and treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disseminated intravascular coagulation: old disease, new hope

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disseminated intravascular coagulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of gabexate mesilate on disseminated intravascular coagulation as a complication of infection developing after abdominal surgery

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights into the protein C pathway: potential implications for the biological activities of drotrecogin alfa (activated).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interactions between inflammation and coagulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haemostatic problems in acute promyelocytic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue factor in hematological malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated protein C up-regulates IL-10 and inhibits tissue factor in blood monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine induction by all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia: triggering the differentiation syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disseminated intravascular coagulation in hematologic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: subanalysis from the phase 3 trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The correlation between platelet activation markers and HMGB1 in patients with disseminated intravascular coagulation and hematologic malignancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: a historical control study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The differentiation syndrome in patients with acute promyelocytic leukemia: experience of the pethema group and review of the literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombomodulin enhances the antifibrinolytic and antileukemic effects of all-trans retinoic acid in acute promyelocytic leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical features and treatment outcomes of six patients with disseminated intravascular coagulation resulting from acute promyelocytic leukemia and treated with recombinant human soluble thrombomodulin at a single institution

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-marketing surveillance of thrombomodulin alfa, a novel treatment of disseminated intravascular coagulation - safety and efficacy in 1,032 patients with hematologic malignancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How we prevent and treat differentiation syndrome in patients with acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombomodulin alfa treatment in patients with acute promyelocytic leukemia and disseminated intravascular coagulation: a retrospective analysis of an open-label, multicenter, post-marketing surveillance study cohort.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A retrospective comparative study of recombinant human thrombomodulin and gabexate mesilate in sepsis-induced disseminated intravascular coagulation patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human thrombomodulin in the treatment of acute myeloid leukemia patients complicated by disseminated intravascular coagulation: retrospective analysis of outcomes between patients treated with heparin and recombinant human thrombomodulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of recombinant human thrombomodulin and gabexate mesylate for treatment of disseminated intravascular coagulation (DIC) with sepsis following emergent gastrointestinal surgery: a retrospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The efficacy of the administration of recombinant human soluble thrombomodulin in patients with DIC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What's new in the pathogenesis of the coagulopathy in acute promyelocytic leukemia?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of Recombinant Human Soluble Thrombomodulin for Disseminated Intravascular Coagulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro studies on the role of recombinant human soluble thrombomodulin in the context of retinoic acid mediated APL differentiation syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30383650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/MD.0000000000012981

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1 May 2020

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1 May 2020

PubMed publication ID

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1 May 2020

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