Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: a historical control study. (Q35558208)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: a historical control study (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Kazuma Yamakawa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Satoshi Fujimi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Tomoyoshi Mohri

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Hiroki Matsuda

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Yasushi Nakamori

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Tomoya Hirose

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Osamu Tasaki

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Hiroshi Ogura

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Yasuyuki Kuwagata

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Takeshi Shimazu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

publication date

11 May 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

page(s)

R123

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis

31 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Combination effect of antithrombin and recombinant human soluble thrombomodulin in a lipopolysaccharide induced rat sepsis model

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Thrombomodulin mutations in atypical hemolytic-uremic syndrome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Adverse outcomes associated with the use of drotrecogin alfa (activated) in patients with severe sepsis and baseline bleeding precautions

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Recombinant human activated protein C: current insights into its mechanism of action

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

SIRS-associated coagulopathy and organ dysfunction in critically ill patients with thrombocytopenia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

The interactions between inflammation and coagulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravascular coagulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Thrombomodulin-protein C-EPCR system: integrated to regulate coagulation and inflammation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Anticoagulant therapy in acute lung injury

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Extracellular histones are major mediators of death in sepsis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Recombinant human soluble thrombomodulin decreases the plasma high-mobility group box-1 protein levels, whereas improving the acute liver injury and survival rates in experimental endotoxemia

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Efficacy and safety of recombinant human activated protein C for severe sepsis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218981

Drotrecogin alfa (activated) (recombinant human activated protein C) reduces host coagulopathy response in patients with severe sepsis

26 September 2018

1 reference

12 December 2020

rhs-TM prevents ET-induced increase in pulmonary vascular permeability through protein C activation

1 reference

12 December 2020

Disseminated intravascular coagulation in sepsis

1 reference

12 December 2020

Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial

1 reference

12 December 2020

Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis

1 reference

12 December 2020

The antithrombotic effects of recombinant human soluble thrombomodulin (rhsTM) on tissue factor-induced disseminated intravascular coagulation in crab-eating monkeys (Macaca fascicularis)

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC10228

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

21569368

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21569368%20AND%20SRC:MED&resulttype=core&format=json