Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk (Q57481447)

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English	Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk	article

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instance of

scholarly article

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title

Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk (English)

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main subject

obesity

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author

Craig Venter

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11

object named as

J Craig Venter

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Amalio Telenti

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12

object named as

Amalio Telenti

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Tim Spector

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8

object named as

Tim D Spector

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Elizabeth T Cirulli

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1

object named as

Elizabeth T Cirulli

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Lining Guo

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2

object named as

Lining Guo

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author name string

Christine Leon Swisher

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3

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Naisha Shah

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4

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Lei Huang

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5

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Lori A Napier

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6

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Ewen F Kirkness

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7

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C Thomas Caskey

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9

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Bernard Thorens

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10

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language of work or name

English

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publication date

8 October 2018

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published in

Cell Metabolism

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volume

29

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issue

2

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page(s)

488-500.e2

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cites work

Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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Independent effects of obesity and cortisol in predicting cardiovascular risk factors in men and women

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Obesity and cortisol

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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What are the physical characteristics associated with a normal metabolic profile despite a high level of obesity in postmenopausal women?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Human Gene Mutation Database (HGMD): 2003 update

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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The metabolically healthy but obese individual presents a favorable inflammation profile

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Clinical review#: Lipodystrophies: genetic and acquired body fat disorders

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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FaST linear mixed models for genome-wide association studies

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Morning cortisol is lower in obese individuals with normal glucose tolerance

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Interplay between lipids and branched-chain amino acids in development of insulin resistance

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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The UK Adult Twin Registry (TwinsUK Resource)

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Cortisol, obesity, and the metabolic syndrome: a cross-sectional study of obese subjects and review of the literature

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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inferred from PubMed ID database lookup

Changes in the serum metabolite profile in obese children with weight loss

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Genetic studies of body mass index yield new insights for obesity biology

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Multi-omic signature of body weight change: results from a population-based cohort study

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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The metabolome profiling and pathway analysis in metabolic healthy and abnormal obesity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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A Metabolomic Approach to Understanding the Metabolic Link between Obesity and Diabetes

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stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Global metabolomic profiling targeting childhood obesity in the Hispanic population

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Hypothalamic-pituitary-adrenal axis dysregulation and cortisol activity in obesity: A systematic review

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Deep sequencing of 10,000 human genomes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Is There an Association Between Cortisol and Hypertension in Overweight or Obese Children?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Metabolomic Profiling of Long-Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Metabolically Healthy Obese and Incident Cardiovascular Disease Events Among 3.5 Million Men and Women

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Prevalence of Obesity Among Adults and Youth: United States, 2015-2016.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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ClinVar: improving access to variant interpretations and supporting evidence

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stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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inferred from PubMed ID database lookup

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolically healthy obese individuals present similar chronic inflammation level but less insulin-resistance than obese individuals with metabolic syndrome

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stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Toward Precision Approaches for the Prevention and Treatment of Obesity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Integrative Personal Omics Profiles during Periods of Weight Gain and Loss.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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inferred from PubMed ID database lookup

Acetaminophen (Paracetamol) Use Modifies the Sulfation of Sex Hormones

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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inferred from PubMed ID database lookup

Being Metabolically Healthy, the Most Responsible Factor for Vascular Health.

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

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Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults.

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

based on heuristic

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Cardiovascular and Metabolic Heterogeneity of Obesity: Clinical Challenges and Implications for Management

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/30318341

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12 December 2020

based on heuristic

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MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/30318341

retrieved

12 December 2020

based on heuristic

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Identifiers

DOI

10.1016/J.CMET.2018.09.022

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PMC publication ID

6370944

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PubMed publication ID

30318341

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