E2F4 loss suppresses tumorigenesis in Rb mutant mice. (Q54798619)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

title

E2F4 loss suppresses tumorigenesis in Rb mutant mice (English)

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16 December 2019

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16 December 2019

Eunice Y Lee

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16 December 2019

Hieu Cam

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16 December 2019

Ulrike Ziebold

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16 December 2019

Jacqueline A Lees

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16 December 2019

Brian David Dynlacht

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16 December 2019

publication date

1 December 2002

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16 December 2019

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16 December 2019

volume

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16 December 2019

issue

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16 December 2019

page(s)

463-472

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Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F.

16 December 2019

cites work

1 reference

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7 January 2021

The retinoblastoma protein pathway and the restriction point

1 reference

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7 January 2021

E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Shared role of the pRB-related p130 and p107 proteins in limb development

1 reference

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7 January 2021

Linking the Rb and polycomb pathways

1 reference

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7 January 2021

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

1 reference

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7 January 2021

Distinct roles for E2F proteins in cell growth control and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

The regulation of E2F by pRB-family proteins

1 reference

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7 January 2021

E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control

1 reference

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7 January 2021

E2F4 is exported from the nucleus in a CRM1-dependent manner.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

E2F-4, a new member of the E2F transcription factor family, interacts with p107

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Regulation of cell proliferation by the E2F transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma

1 reference

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7 January 2021

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

1 reference

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7 January 2021

E2F-5, a new E2F family member that interacts with p130 in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

E2F4 is essential for normal erythrocyte maturation and neonatal viability

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Effects of an Rb mutation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members

1 reference

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7 January 2021

Targeted disruption of p107: functional overlap between p107 and Rb

1 reference

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7 January 2021

Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Induction of S-Phase Entry by E2F Transcription Factors Depends on Their Nuclear Localization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

The retinoblastoma gene family: cousins with overlapping interests

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Early loss of the retinoblastoma gene is associated with impaired growth inhibitory innervation during melanotroph carcinogenesis in Rb+/- mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

1 reference

7 January 2021

Sibling rivalry in the E2F family

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

E2F Activity Is Regulated by Cell Cycle-Dependent Changes in Subcellular Localization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

The E2F1-3 transcription factors are essential for cellular proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6

7 January 2021

10.1016/S1535-6108(02)00207-6

Identifiers

DOI

1 reference

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16 December 2019

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