The retinoblastoma protein pathway and the restriction point (Q41239146)

28 September 2017

1 reference

title

The retinoblastoma protein pathway and the restriction point (English)

1 reference

28 September 2017

1 reference

1 reference

28 September 2017

Bartek J

1 reference

28 September 2017

Bartkova J

series ordinal

1 reference

28 September 2017

publication date

1 December 1996

1 reference

Current Opinion in Cell Biology

28 September 2017

published in

1 reference

28 September 2017

1 reference

28 September 2017

1 reference

28 September 2017

page(s)

805-814

1 reference

G1 events and regulation of cell proliferation

28 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

What is the restriction point?

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Unrestricted cell cycling and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Repression of RNA polymerase III transcription by the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Shared role of the pRB-related p130 and p107 proteins in limb development

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Targeted disruption of p107: functional overlap between p107 and Rb

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Detection of a novel cell cycle-regulated kinase activity that associates with the amino terminus of the retinoblastoma protein in G2/M phases

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Different roles for cyclins D1 and E in regulation of the G1-to-S transition

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Growth suppression by p16ink4 requires functional retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Cyclin A-associated kinase activity is rate limiting for entrance into S phase and is negatively regulated in G1 by p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Cyclin-dependent kinases and pRb: regulators of the proliferation-differentiation switch

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Cell cycle regulation of the murine cyclin E gene depends on an E2F binding site in the promoter.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Regulation of the cyclin E gene by transcription factor E2F1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Developmental control of the G1 to S transition in Drosophila: cyclin Eis a limiting downstream target of E2F

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Cdk inhibitors in development and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Translational control of p27Kip1 accumulation during the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Rescue of defective mitogenic signaling by D-type cyclins.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Thyrotropin induces G1 cyclin expression and accelerates G1 phase after insulin-like growth factor I stimulation in FRTL-5 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Inhibition of p53-mediated growth arrest by overexpression of cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980081-0

7 January 2021

10.1016/S0955-0674(96)80081-0

Identifiers

DOI

1 reference

28 September 2017

1 reference