The pan-histone deacetylase inhibitor CR2408 disrupts cell cycle progression, diminishes proliferation and causes apoptosis in multiple myeloma cells. (Q54539131)

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English	The pan-histone deacetylase inhibitor CR2408 disrupts cell cycle progression, diminishes proliferation and causes apoptosis in multiple myeloma cells.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22211565

The pan-histone deacetylase inhibitor CR2408 disrupts cell cycle progression, diminishes proliferation and causes apoptosis in multiple myeloma cells. (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22211565

author name string

Philipp Baumann

1

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22211565

Carmen Junghanns

2

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Europe PubMed Central

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31 May 2018

http://europepmc.org/abstract/MED/22211565

Sonja Mandl-Weber

3

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Europe PubMed Central

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31 May 2018

http://europepmc.org/abstract/MED/22211565

Stefan Strobl

4

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Europe PubMed Central

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31 May 2018

http://europepmc.org/abstract/MED/22211565

Fuat Oduncu

5

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22211565

Ralf Schmidmaier

6

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31 May 2018

http://europepmc.org/abstract/MED/22211565

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publication date

23 December 2011

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31 May 2018

http://europepmc.org/abstract/MED/22211565

British Journal of Haematology

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31 May 2018

http://europepmc.org/abstract/MED/22211565

156

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31 May 2018

http://europepmc.org/abstract/MED/22211565

5

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31 May 2018

http://europepmc.org/abstract/MED/22211565

633-642

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Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22211565

Phase I study of vorinostat in combination with bortezomib for relapsed and refractory multiple myeloma

1 reference

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Histone deacetylase inhibitors as anti-neoplastic agents.

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Anticancer activities of histone deacetylase inhibitors

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NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma

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The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo

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The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes.

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The effects of JNJ-26481585, a novel hydroxamate-based histone deacetylase inhibitor, on the development of multiple myeloma in the 5T2MM and 5T33MM murine models.

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Bortezomib alone or in combination with the histone deacetylase inhibitor JNJ-26481585: effect on myeloma bone disease in the 5T2MM murine model of myeloma.

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A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts

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The histone deacetylase inhibitor, PXD101, potentiates bortezomib-induced anti-multiple myeloma effect by induction of oxidative stress and DNA damage

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KD5170, a novel mercaptoketone-based histone deacetylase inhibitor, exerts antimyeloma effects by DNA damage and mitochondrial signaling

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

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A phase II multiple dose clinical trial of histone deacetylase inhibitor ITF2357 in patients with relapsed or progressive multiple myeloma

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Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2

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Analysis of histone deacetylase inhibitor, depsipeptide (FR901228), effect on multiple myeloma

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21 January 2018

Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma

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Cancer. p53, guardian of the genome

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Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression

1 reference

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The histone deacetylase inhibitor LBH589 is a potent antimyeloma agent that overcomes drug resistance.

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21 January 2018

The novel inhibitor of histone deacetylase resminostat (RAS2410) inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells

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A work in progress: the clinical development of histone deacetylase inhibitors

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Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications

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Emerging treatments for multiple myeloma: beyond immunomodulatory drugs and bortezomib

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21 January 2018

Molecular sequelae of histone deacetylase inhibition in human malignant B cells

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21 January 2018

Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors

1 reference

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21 January 2018

Multiple myeloma

1 reference

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21 January 2018

Phase I trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) in patients with advanced multiple myeloma

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21 January 2018

The INK4 family of cell cycle inhibitors in cancer

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Growing roles for the mTOR pathway

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HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity

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Acetylation is indispensable for p53 activation

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Histone deacetylase inhibitors: understanding a new wave of anticancer agents

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Requirement of Hos2 histone deacetylase for gene activity in yeast

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A fluorogenic histone deacetylase assay well suited for high-throughput activity screening

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The novel histone deacetylase inhibitor, AR‐42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells

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Combined functional and molecular analysis of tumor cell signaling defines 2 distinct myeloma subgroups: Akt-dependent and Akt-independent multiple myeloma

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21 January 2018

Identifiers

10.1111/J.1365-2141.2011.08983.X

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22211565

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22211565

ResearchGate publication ID

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