The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo (Q33896749)

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English	The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo	scientific article

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Europe PubMed Central

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29 July 2017

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Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

6

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Paul Dent

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Europe PubMed Central

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29 July 2017

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Girija Dasmahapatra

1

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Europe PubMed Central

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29 July 2017

Dmitry Lembersky

2

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Europe PubMed Central

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29 July 2017

Lora Kramer

3

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Europe PubMed Central

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29 July 2017

Richard I Fisher

4

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Europe PubMed Central

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29 July 2017

Jonathan Friedberg

5

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29 July 2017

Steven Grant

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29 July 2017

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16 March 2010

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29 July 2017

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29 July 2017

115

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29 July 2017

22

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Europe PubMed Central

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29 July 2017

4478-4487

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Europe PubMed Central

PubMed publication ID

29 July 2017

Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes

1 reference

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5 July 2018

Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome

1 reference

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5 July 2018

Phase I study of vorinostat in combination with bortezomib for relapsed and refractory multiple myeloma

1 reference

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5 July 2018

Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells

1 reference

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5 July 2018

PCI-24781 induces caspase and reactive oxygen species-dependent apoptosis through NF-kappaB mechanisms and is synergistic with bortezomib in lymphoma cells

1 reference

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Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.

1 reference

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Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma

1 reference

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5 July 2018

Bcl-2 antagonists interact synergistically with bortezomib in DLBCL cells in association with JNK activation and induction of ER stress

1 reference

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5 July 2018

Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitor-induced apoptosis

1 reference

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DNA replication arrest in response to genotoxic stress provokes early activation of stress-activated protein kinases (SAPK/JNK).

1 reference

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Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors

1 reference

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5 July 2018

Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions

1 reference

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Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor-induced DNA damage in vitro and in vivo in human multiple myeloma cells

1 reference

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Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein

1 reference

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Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia

1 reference

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5 July 2018

Phase II trial of oral vorinostat (suberoylanilide hydroxamic acid) in relapsed diffuse large-B-cell lymphoma

1 reference

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5 July 2018

Interactions between bortezomib and romidepsin and belinostat in chronic lymphocytic leukemia cells

1 reference

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RAC3 down-regulation sensitizes human chronic myeloid leukemia cells to TRAIL-induced apoptosis.

1 reference

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Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma

1 reference

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5 July 2018

Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma

1 reference

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5 July 2018

Anticancer activities of histone deacetylase inhibitors

1 reference

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5 July 2018

Aggresome induction by proteasome inhibitor bortezomib and alpha-tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881506

5 July 2018

United States Food and Drug Administration approval summary: bortezomib for the treatment of progressive multiple myeloma after one prior therapy

1 reference

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5 July 2018

Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis

1 reference

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5 July 2018

The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism

1 reference

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Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression-based survival prediction

1 reference

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Blockade of histone deacetylase inhibitor-induced RelA/p65 acetylation and NF-kappaB activation potentiates apoptosis in leukemia cells through a process mediated by oxidative damage, XIAP downregulation, and c-Jun N-terminal kinase 1 activation

1 reference

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Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors

1 reference

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Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells.

1 reference

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Histone deacetylase inhibitors specifically kill nonproliferating tumour cells

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Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

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Genomic instability in mice lacking histone H2AX

1 reference

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NF-kappa B as a therapeutic target in multiple myeloma

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Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells

1 reference

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The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

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The DNA damage response: putting checkpoints in perspective

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Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts

1 reference

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Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells.

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29 October 2018

Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome

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A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

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29 October 2018

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Bortezomib or high-dose dexamethasone for relapsed multiple myeloma

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Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.

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Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells

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CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma

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29 October 2018

Identifiers

10.1182/BLOOD-2009-12-257261

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Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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