The p16INK4a/CDKN2A tumor suppressor and its relatives. (Q54317457)

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Deletion analysis of the p16 tumour suppressor gene in phaeochromocytomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Genetic status and expression of the cyclin-dependent kinase inhibitors in human gastric carcinoma cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Frequent allele loss on 9p21-22 defines a smallest common region in the vicinity of the CDKN2 gene in sporadic breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Functional analysis of wild-type and malignant glioma derived CDKN2Aβ alleles: Evidence for an RB-independent growth suppressive pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Point mutations can inactivate in vitro and in vivo activities of p16(INK4a)/CDKN2A in human glioma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Decreased expression of the p16/MTS1 gene without mutation is frequent in human urinary bladder carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

P16 deletion and mutation analysis in human brain tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The retinoblastoma protein pathway and the restriction point

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Reduced survival in patients with ductal pancreatic adenocarcinoma associated with CDKN2 mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Frequent mutations of CDKN2 in primary pancreatic adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Deletion and differential expression of p16INK4a in mouse lung tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Infrequent CDKN2 (MTS1/p16) gene alterations in human primary breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

G1 control gene status is frequently altered in resectable non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

CpG-rich islands and the function of DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Structural characterization of the tumor suppressor p16, an ankyrin-like repeat protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Open questions on p16

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p16INK4/p15INK4B gene inactivation is a frequent event in malignant T-cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally?

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Rates of p16 (MTS1) mutations in primary tumors with 9p loss

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Status and expression of thep16INK4 gene in human thyroid tumors and thyroid-tumor cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loh and mutation analysis ofCDKN2 in primary human ovarian cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Assignment of the gene for methylthioadenosine phosphorylase to human chromosome 9 by mouse-human somatic cell hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Restoration of CDKN2A into melanoma cells induces morphologic changes and reduction in growth rate but not anchorage-independent growth reversal

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutational analysis of the p16 gene in human neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Molecular deletion of 9p sequences in non‐small cell lung cancer and malignant mesothelioma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p16 tumor suppressor gene mutations in Chinese esophageal carcinomas in Hong Kong.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loss of expression of the p16 gene is frequent in malignant skin tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Informative MspI polymorphism adjacent to exon 3 of the p16INK4 (MTS1) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Absence of p16/MTS1 gene mutations in human prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Multigenetic lesions in infant acute leukaemias: correlations with ALL-1 gene status

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Cytogenetic analysis of melanocytes from premalignant nevi and melanomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

MTS1 gene mutations in archival oral squamous cell carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Alterations of CDKN2 (p16) in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Biochemical characterization of p16INK4- and p18-containing complexes in human cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The human protein p19ARF is not detected in hemopoietic human cell lines that abundantly express the alternative beta transcript of the p16INK4a/MTS1 gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

High frequency of chromosome 9 deletion in ovarian cancer: evidence for three tumour-suppressor loci.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Deletions of Interferon Genes in Acute Lymphoblastic Leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous deletion of the alpha- and beta 1-interferon genes in human leukemia and derived cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The p16 and p18 tumor suppressor genes in neuroblastoma: implications for drug resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Increased expression of cyclin-dependent kinase inhibitor 2 (CDKN2A) gene product P16INK4A in ovarian cancer is associated with progression and unfavourable prognosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Retinoblastoma and p16 proteins in mammary carcinoma: their relationship to cyclin D1 and histopathological parameters

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loss of heterozygosity on chromosome 9 in human breast cancer: Association with clinical variables and genetic changes at other chromosome regions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Identification of human tumour suppressor genes by monochromosome transfer: rapid growth-arrest response mapped to 9p21 is mediated solely by the cyclin-D-dependent kinase inhibitor gene, CDKN2A (p16INK4A).

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Low frequency of p16/CDKN2 gene mutations in esophageal carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

P16INK4A gene homozygous deletions in human acute leukaemias with alterations of chromosome 9

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Analysis of the CDKN2A, CDKN2B and CDK4 genes in 48 Australian melanoma kindreds

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous deletions within human chromosome band 9p21 in melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Genetic and physical map of the interferon region on chromosome 9p.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Induction of p18INK4c and its predominant association with CDK4 and CDK6 during myogenic differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A frequent polymorphism in exon 1 of the p16/CDKN2 gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Alteration of p16 and p15 genes in common epithelial ovarian tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Cumulative prognostic value of p16/CDKN2 and p53 oncoprotein expression in premalignant laryngeal lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Molecular analysis of the cyclin-dependent kinase inhibitor genes p15INK4b/MTS2, p16INK4/MTS1, p18 and p19 in human cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Spontaneous transformation of rat ovarian surface epithelial cells: association with cytogenetic changes and implications of repeated ovulation in the etiology of ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Increased Risk of Pancreatic Cancer in Melanoma-Prone Kindreds withp16INK4Mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Replicative senescence: the human fibroblast comes of age.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Frequent loss of the cyclin-dependent kinase-4 inhibitor gene in human gliomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutation analysis of the p53, APC, and p16 genes in the Barrett's oesophagus, dysplasia, and adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

High Frequency of Chromosome 9p Allelic Loss and CDKN2 Tumor Suppressor Gene Alterations in Squamous Cell Carcinoma of the Bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

CDKN2 explains part of the clinical phenotype in Dutch familial atypical multiple-mole melanoma (FAMMM) syndrome families.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Deletion mapping indicates that MTS1 is the target of frequent deletions at chromosome 9p21 in paediatric acute lymphoblastic leukaemias.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Germline Mutations of the CDKN2 Gene in UK Melanoma Families

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The current situation with regard to human melanoma and genetic inferences.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Infrequent Mutation of p16INK4 in Sporadic Melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Hemizygous or homozygous deletion of the chromosomal region containing the p16INK4a gene is associated with amplification of the EGF receptor gene in glioblastomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutations and polymorphisms in the p53, p21 and p16 genes in oral carcinomas of Indian betel quid chewers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loss of the p16/MTS1 tumor suppressor gene causes E2F-mediated deregulation of essential enzymes of the DNA precursor metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Sequence variation and chromosomal mapping of the murine Cdkn2a tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Prognostic importance of p15INK4B and p16INK4 gene inactivation in childhood acute lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Molecular genetic basis of renal carcinogenesis in the Eker rat model of tuberous sclerosis (Tsc2)

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p16INK4, pRB, p53 and cyclin D1 expression and hypermethylation of CDKN2 gene in thymoma and thymic carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Inactivation of p16INK4 in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Germline p16 mutations in familial melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Inactivation of p16/CDKN2 and p15/MTS2 genes in different histological types and clinical stages of primary ovarian tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Highly frequent homozygous deletion of the p16 gene in esophageal cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

High frequency of homozygous deletions of CDK4I gene in childhood acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Analysis of cyclin-dependent kinase inhibitor genes (CDKN2A, CDKN2B, andCDKN2C) in childhood rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Concomitant presence of p16/cyclin-dependent kinase 4 and cyclin D/cyclin-dependent kinase 4 complexes in LNCaP prostatic cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Abnormalities of the P16INK4A gene in thyroid cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous deletions of p16INK4A/MTS1 and p15INK4B/MTS2 genes in glioma cells and primary glioma tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Potential role for concurrent abnormalities of the cyclin D1, p16CDKN2 and p15CDKN2B genes in certain B cell non-Hodgkin's lymphomas. Functional studies in a cell line (Granta 519).

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Partial deletions of the CDKN2 and MTS2 putative tumor suppressor genes in a myxoid chondrosarcoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Comparative analysis of Homo sapiens and Mus musculus cyclin-dependent kinase (CDK) inhibitor genes p16 (MTS1) and p15 (MTS2)

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

High frequency deletion of the tumour suppressor gene P16INK4a (MTS1) in human thyroid cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Infrequent somatic mutation of the MTS1 gene in primary bladder carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

NMR structural characterization of the CDK inhibitor p19INK4d.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Alterations of the p16INK4A gene in human ovarian cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Molecular analysis of a family of cyclin-dependent kinase inhibitor genes (p15/MTS2/INK4b and p18/INK4c) in non-small cell lung cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Molecular analysis of the cyclin-dependent kinase inhibitor family: p16(CDKN2/MTS1/INK4A), p18(INK4C) and p27(Kip1) genes in neuroblastomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Differential inactivation of CDKN2 and Rb protein in non-small-cell and small-cell lung cancer cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

CDKN2 in HPV-positive and HPV-negative cervical-carcinoma cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loss of heterozygosity at 9p and 17q in human laryngeal tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Contribution of Chromosome 9p21‐22 Deletion to the Progression of Human Renal Cell Carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Infrequent alterations of the p16INK4A gene in liver cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Histopathology, classification, and grading of gliomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Suppression of tumorigenicity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutation and cancer: statistical study of retinoblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutational analysis of CDKN2 (CDK4I/MTS1) gene in tissues and cell lines of human prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A possible subgroup of ALL with 9p-

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Immunohistochemical analysis of the p16INK4 cyclin-dependent kinase inhibitor in malignant mesothelioma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutations of the INK4a locus in squamous cell carcinomas of human skin.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Primary malignant lymphoma of the brain: demonstration of frequent p16 and p15 gene deletions.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutations in the CDKN2A ( p16INK4a ) gene in microdissected sporadic primary melanomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Cyclin dependent kinase regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Transforming Growth Factor β Activates the Promoter of Cyclin-dependent Kinase Inhibitor p15 through an Sp1 Consensus Site

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Establishment, characterization and drug sensitivity of four new human soft tissue sarcoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Cancer-associated mis-sense and deletion mutations impair p16INK4 CDK inhibitory activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Characterization of chromosome 9 deletions in transitional cell carcinoma by microsatellite assay

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Human T-cell leukemia virus type 1 Tax releases cell cycle arrest induced by p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Structure of the cyclin-dependent kinase inhibitor p19Ink4d

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Cytogenetics of non-small cell lung cancer: analysis of consistent non-random abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous deletions and loss of expression of the CDKN2 gene occur frequently in head and neck squamous cell carcinoma cell lines but infrequently in primary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Genetic heterogeneity in familial malignant melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p16 (CDKN2/MTS1) Gene Deletions are Rare in Prostatic Carcinomas in the United States and Japan

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Alterations of P16 (MTS1) in node-positive non-small cell lung carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Hypermethylation of a 5′ CpG island of p16 is a frequent event in non-Hodgkin’s lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A challenge to p16 gene as a major tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Alterations of p16/CDKN2, p53 and ras genes in oral squamous cell carcinomas and premalignant lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Increase in radiation sensitivity of human malignant melanoma cells by expression of wild-type p16 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Ankyrin for clues about the function of p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Growth suppression by p16ink4 requires functional retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Identification of G1 kinase activity for cdk6, a novel cyclin D partner

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Alterations of the p15, p16,and p18 genes in osteosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The p19INK4D Cyclin dependent kinase inhibitor gene is altered in osteosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Increased radiosensitivity of p16 gene-deleted human glioma cells after transfection with wild-type p16 gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Allelotype analysis in mouse hepatocellular carcinomas; frequent homozygous deletion of mouse homolog of p16/CDKN2 gene on chromosome 4 in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous deletion of mouse homolog of p16/CDKN2 gene on chromosome 4 in mouse liver epithelial cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Principles of CDK regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Transcriptional and posttranscriptional regulation of exogenous human beta interferon gene in simian cells defective in interferon synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Expression of the cyclin‐dependent kinase inhibitors p16INK4, p15INK4B and p21Waf1/cip1 in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loss of heterozygosity on chromosome 9 andp16 (MTS1, CDKN2) gene mutations in esophageal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A CDKN2-like polymorphism in Xiphophorus LG V is associated with UV-B-induced melanoma formation in platyfish-swordtail hybrids

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Molecular analysis of the cyclin-dependent kinase inhibitor genes, p15, p16, p18 and p19 in the myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Structural integrity of the cyclin‐dependent kinase inhibitor genes, p15, p16 and p18 in myeloid leukaemias

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Alterations of multiple tumor suppressor genes (p53 (17p13), p16INK4 (9p21), and DBM (13q14)) in B-cell chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Ordering S phase and M phase in the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Activation but not inactivation of the MTS1 gene is associated with primary colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Deletion mapping of chromosome region 9p21-p22 surrounding the CDKN2 locus in melanoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Infrequent somatic alteration of p16/MTS1 in human primary superficial bladder cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutations and altered expression of p16INK4 in human cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Molecular cloning, expression pattern, and chromosomal localization of human CDKN2D/INK4d, an inhibitor of cyclin D-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Alterations of the p16 gene in head and neck cancer: frequency and association with p53, PRAD-1 and HPV

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous deletions of the CDKN2/p16 gene in dural hemangiopericytomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Deletion of the p16 and p15 Genes in Human Bladder Tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Leukocyte and fibroblast interferon genes are located on human chromosome 9

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous deletions but no sequence mutations in coding regions of p15 or p16 in human primary bladder tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Frequent inactivation of p16INK4a in oral premalignant lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

G1 events and regulation of cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Molecular analysis of the INK4 family of genes in prostate carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Temperature-sensitive mutants of p16CDKN2 associated with familial melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Low frequency of CDKN2 mutation in endometrial carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The D-type cyclins and their role in tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Common alternative gene alterations in adult malignant astrocytomas, but not in childhood primitive neuroectodermal tumors: P 16ink4 homozygous deletions and CDK4 gene amplifications.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p16/CDKN2 andCDK4 gene mutations in sporadic melanoma development and progression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Screening of germline mutations in the CDKN2A and CDKN2B genes in Swedish families with hereditary cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutational analysis of the CDKN2 gene in metastases from patients with cutaneous malignant melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Genes involved in cell cycle G1 checkpoint control are frequently mutated in human melanoma metastases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Analysis of p16 gene deletion and point mutation in breast carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Transfer of p16inka/CDKN2 gene in leukaemic cell lines inhibits cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 gene in human central nervous system primitive neuroectodermal tumor.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutations associated with familial melanoma impair p16INK4 function.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Differential expression of p16INK4a and p16beta transcripts in B-lymphoblastoid cells from members of hereditary melanoma families without CDKN2A exon mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Analysis of MTS1/CDK4 in female breast carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Intragenic mutations of the p16(INK4), p15(INK4B) and p18 genes in primary non-small-cell lung cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Alterations of tumor suppressor genes and the H-ras oncogene in oral squamous cell carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loss of heterozygosity on the short arm of chromosome 9 without p16 gene mutation in gastric carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-alpha in hematopoietic cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Infrequent alterations of the p15, p16, CDK4 and cyclin D1 genes in non-astrocytic human brain tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Chromosome-9 loss detected by fluorescence in situ hybridization in bladder cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loss of heterozygosity on chromosome 9q21 (p16 gene) uncommon in soft-tissue sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

CDKN2 gene deletion is not found in chronic lymphoid leukaemias of B- and T-cell origin but is frequent in acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Sporadic CDKN2 (MTS1/p16ink4) gene alterations in human ovarian tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Expression and regulation of G1 cell-cycle inhibitors (p16INK4A, p15INK4B, p18INK4C, p19INK4D) in human acute myeloid leukemia and normal myeloid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Involvement of the cyclin-dependent kinase-4 inhibitor (CDKN2) gene in the pathogenesis of lymphoid blast crisis of chronic myelogenous leukaemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A role for both RB and p53 in the regulation of human cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

G1 phase progression: cycling on cue

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

1 reference

7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p16 overexpression: a potential early indicator of transformation in ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loss of heterozygosity at 9p21 loci and mutations of the MTS1 and MTS2 genes in human lung cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Two tracks but one race? Cancer genetics

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Analysis of the novel cyclin-dependent kinase 4 and 6 inhibitor gene p18 in lymphoma and leukemia cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukaemia cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutational analysis of the p15 and p16 genes in acute leukaemias

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Replicative senescence: implications for in vivo aging and tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The 5'-flanking region of the E1 alpha form of the murine p16INK4a (MTS1) gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Expression of the cyclin‐dependent kinase inhibitor p16 during the ongoing cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group [published erratum appears in Hum Mol Genet 1998 May;7(5):941]

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loss of cyclin-dependent kinase inhibitor genes and chromosome 9 karyotypic abnormalities in human bladder cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Suppression of growth in vitro and tumorigenicity in vivo of human carcinoma cell lines by transfected p16INK4.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

P16 gene in uncultured tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The 9p21 region in bladder cancer cell lines: large homozygous deletion inactivate the CDKN2, CDKN2B and MTAP genes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Origins of G1 arrest in senescent human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

CDKN2A mutation in a non-FAMMM kindred with cancers at multiple sites results in a functionally abnormal protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Intragenic mutations of CDKN2B and CDKN2A in primary human esophageal cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Frequent aberrant methylation of p16INK4a in primary rat lung tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Assignment of 12 loci to rat chromosome 5: evidence that this chromosome is homologous to mouse chromosome 4 and to human chromosomes 9 and 1 (1p arm)

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p16/CDKN2 gene and p53 gene alterations in Japanese non-smoking female lung adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Loss of expression of thep16INK4/CDKN2 gene in cutaneous malignant melanoma correlates with tumor cell proliferation and invasive stage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous deletions of p16(INK4) occur frequently in bilharziasis-associated bladder cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p16 mutations/deletions are not frequent events in prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Multiple types of aberrations in the p16 (INK4a) and the p15(INK4b) genes in 30 esophageal squamous-cell-carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Analysis of the p16INK4A, p15INK4B and p18INK4C genes in multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Deletion and transfection analysis of the p15/MTS2 gene in malignant gliomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Localization of the interferon-alpha gene cluster to rat chromosome bands 5q31----q33 by fluorescence in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Tumor suppressor p16INK4A: structural characterization of wild-type and mutant proteins by NMR and circular dichroism

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Infrequent CDKN2 mutation in human differentiated thyroid cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The CDKN2 gene alterations in various types of adult T-cell leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Induction of senescence in human malignant glioma cells by p16INK4A.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Distinct roles for cyclin-dependent kinases in cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Crystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Prognostic implications of cyclins (D1, E, A), cyclin-dependent kinases (CDK2, CDK4) and tumor-suppressor genes (pRb, p16INK4A) in childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Homozygous deletions of the MTS1 gene are rare in non-astrocytic brain tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Mutations of the CDKN2/p16INK4 gene in Australian melanoma kindreds

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Localization of a putative tumor suppressor gene by using homozygous deletions in melanomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A Familial Syndrome of Pancreatic Cancer and Melanoma with a Mutation in theCDKN2Tumor-Suppressor Gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

p16 (CDKN2) is a major deletion target at 9p21 in bladder cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Allelotyping of butadiene-induced lung and mammary adenocarcinomas of B6C3F1 mice: frequent losses of heterozygosity in regions homologous to human tumor-suppressor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Differential CDK-inhibitor gene expression in aging human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Intragenic homozygous deletions of MTS1 gene in gastric cancer in Taiwan.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Growth arrest and suppression of tumorigenicity of bladder-carcinoma cell lines induced by the P16/CDKN2 (p16INK4A, MTS1) gene and other loci on human chromosome 9

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Lack of p16/CDKN2 alterations in thyroid carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Analysis of p16INK4aand Its Interaction with CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Familial tumor syndrome associated with a germline nonfunctional p16INK4a allele

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Infrequent mutations of p16INK4A and p15INK4B genes in human pituitary adenomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Codeletion of the genes for p16INK4, methylthioadenosine phosphorylase, interferon-alpha1, interferon-beta1, and other 9p21 markers in human malignant cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Genomic DNA and messenger RNA expression alterations of the CDKN2B and CDKN2 genes in esophageal squamous carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021

Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1

7 January 2021