RAF265, a dual BRAF and VEGFR2 inhibitor, prevents osteoclast formation and resorption. Therapeutic implications. (Q43845117)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

RAF265, a dual BRAF and VEGFR2 inhibitor, prevents osteoclast formation and resorption. Therapeutic implications (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Atanasio Pandiella

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Antonio Garcia-Gomez

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

publication date

7 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json

Investigational New Drugs

7 February 2020

published in

1 reference

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7 February 2020

volume

1 reference

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7 February 2020

issue

1 reference

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7 February 2020

page(s)

200-205

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json

Targeting BRAF for patients with melanoma.

7 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Design and synthesis of orally bioavailable benzimidazoles as Raf kinase inhibitors

21 January 2018

1 reference

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Malignant melanoma: genetics and therapeutics in the genomic era.

21 January 2018

1 reference

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Protein and lipid kinase inhibitors as targeted anticancer agents of the Ras/Raf/MEK and PI3K/PKB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Use of DNA Microarray and Small Animal Positron Emission Tomography in Preclinical Drug Evaluation of RAF265, a Novel B-Raf/VEGFR-2 Inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

alphavbeta3 and macrophage colony-stimulating factor: partners in osteoclast biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Vascular endothelial growth factor acts as an osteolytic factor in breast cancer metastases to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

The molecular understanding of osteoclast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Osteoclast lineage and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Involvement of alpha(v)beta3 integrins in osteoclast function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Macrophage inflammatory protein-1α induces osteoclast formation by activation of the MEK/ERK/c-Fos pathway and inhibition of the p38MAPK/IRF-3/IFN-β pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Plasminogen activators are involved in the degradation of bone by osteoclasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

Osteoporosis: now and the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9845-3

VEGF enhancement of osteoclast survival and bone resorption involves VEGF receptor-2 signaling and beta3-integrin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22773056

12 December 2020

inferred from PubMed ID database lookup

Osteoclastogenesis--current knowledge and future perspectives.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22773056

12 December 2020

inferred from PubMed ID database lookup

Vascular endothelial growth factor receptors in osteoclast differentiation and function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22773056

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S10637-012-9845-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 February 2020

1031138028

0 references

Fatcat ID

release_ae6afsem3velfchn3jx5em2j4q

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ae6afsem3velfchn3jx5em2j4q

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22773056%20AND%20SRC:MED&resulttype=core&format=json