Molecular docking, structure-activity relationship and biological evaluation of the anticancer drug monastrol as a pteridine reductase inhibitor in a clinical isolate of Leishmania donovani (Q43046133)

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scientific article published on 2 June 2010

Language	Label	Description	Also known as
English	Molecular docking, structure-activity relationship and biological evaluation of the anticancer drug monastrol as a pteridine reductase inhibitor in a clinical isolate of Leishmania donovani	scientific article published on 2 June 2010

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Molecular docking, structure-activity relationship and biological evaluation of the anticancer drug monastrol as a pteridine reductase inhibitor in a clinical isolate of Leishmania donovani (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

1 reference

ChEBI release 2020-05-28

Leishmania donovani

object named as

Leishmania donovani

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

2

object named as

Shyam Sundar

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

author name string

Jaspreet Kaur

1

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Neeloo Singh

3

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

language of work or name

0 references

publication date

2 June 2010

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Journal of Antimicrobial Chemotherapy

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

65

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

1742-1748

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

Comparative genomics: from genotype to disease phenotype in the leishmaniases

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Immunopathogenesis of infection with the visceralizing Leishmania species

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Injectable paromomycin for Visceral leishmaniasis in India

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Leishmania donovani pteridine reductase 1: biochemical properties and structure-modeling studies

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Biologically active dihydropyrimidones of the Biginelli-type--a literature survey

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

100 years of the biginelli dihydropyrimidine synthesis

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Leishmania donovani: a glycosyl dihydropyridine analogue induces apoptosis like cell death via targeting pteridine reductase 1 in promastigotes

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

An orally effective dihydropyrimidone (DHPM) analogue induces apoptosis-like cell death in clinical isolates of Leishmania donovani overexpressing pteridine reductase 1.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Leishmania donovani: oral therapy with glycosyl 1,4-dihydropyridine analogue showing apoptosis like phenotypes targeting pteridine reductase 1 in intracellular amastigotes

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Predicting new molecular targets for known drugs

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Comparative protein modelling by satisfaction of spatial restraints

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Pteridine reductase mechanism correlates pterin metabolism with drug resistance in trypanosomatid parasites

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Antileishmanial activity of nano-amphotericin B deoxycholate

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Overexpression in Escherichia coli and purification of pteridine reductase (PTR1) from a clinical isolate of Leishmania donovani.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Novel mechanism of drug resistance in kala azar field isolates

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Essential protein-protein interactions between Plasmodium falciparum thymidylate synthase and dihydrofolate reductase domains

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKQ189

21 January 2018

Identifiers

10.1093/JAC/DKQ189

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

ResearchGate publication ID

0 references

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