Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies. (Q42810702)

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English	Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies.	scientific article

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20 January 2020

Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies (English)

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20 January 2020

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J Iqbal

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R J Deleeuw

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G Srivastava

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W Tam

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H Geng

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D Klinkebiel

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J K Christman

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K Patel

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K Cao

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L Shen

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I F L Tsui

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H Ali

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N Shimizu

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W Y Au

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20 January 2020

W L Lam

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W C Chan

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publication date

5 February 2009

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20 January 2020

23

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6

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1139-1151

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20 January 2020

describes a project that uses

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Natural killer-cell malignancies: diagnosis and treatment

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7 January 2021

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Comparative genomic hybridization study of nasal-type NK/T-cell lymphoma

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Multicolor-FISH analysis of a natural killer cell line (NK-92).

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7 January 2021

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Genome-wide array-based comparative genomic hybridization of natural killer cell lymphoma/leukemia: different genomic alteration patterns of aggressive NK-cell leukemia and extranodal Nk/T-cell lymphoma, nasal type.

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

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Consistent patterns of allelic loss in natural killer cell lymphoma

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7 January 2021

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Comparative genomic hybridization analysis of natural killer cell lymphoma/leukemia. Recognition of consistent patterns of genetic alterations

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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Genetic changes in natural killer cell neoplasms

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

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Identification of del(6)(q21q25) as a recurring chromosomal abnormality in putative NK cell lymphoma/leukaemia

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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Deletion mapping of the long arm of chromosome 6 in peripheral T and NK cell lymphomas

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7 January 2021

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Assembly of microarrays for genome-wide measurement of DNA copy number

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7 January 2021

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A tiling resolution DNA microarray with complete coverage of the human genome

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Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes.

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7 January 2021

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Analysis of chromosome 6q deletion in EBV-associated NK cell leukaemia/lymphoma

1 reference

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7 January 2021

based on heuristic

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Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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Cell type-specific activation of the cytomegalovirus promoter by dimethylsulfoxide and 5-aza-2'-deoxycytidine

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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Significance of PRDM1beta expression as a prognostic marker in diffuse large B-cell lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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A comprehensive analysis of common copy-number variations in the human genome

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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The pathology of NK-cell lymphomas and leukemias

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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Chromosomal translocations are common in natural killer-cell lymphoma/leukemia as shown by spectral karyotyping

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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Cytogenetic abnormalities in natural killer cell lymphoma/leukaemia--is there a consistent pattern?

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

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AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

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Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

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based on heuristic

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The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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A 2.6 Mb interval on chromosome 6q25.2-q25.3 is commonly deleted in human nasal natural killer/T-cell lymphoma.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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AIM1, a novel non-lens member of the betagamma-crystallin superfamily, is associated with the control of tumorigenicity in human malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

inferred from DOI database lookup

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

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The role of autophagy during the early neonatal starvation period

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

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Autophagy in cancer: good, bad, or both?

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

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Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

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Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

based on heuristic

inferred from DOI database lookup

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

1 reference

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7 January 2021

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Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site.

1 reference

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Cytosine methylation does not affect binding of transcription factor Sp1

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based on heuristic

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Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated

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https://api.crossref.org/works/10.1038%2FLEU.2009.3

7 January 2021

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Identifiers

10.1038/LEU.2009.3

1 reference

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20 January 2020

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20 January 2020

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