Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis (Q42816270)

7 November 2017

title

Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis (English)

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7 November 2017

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Rosenwald IB

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7 November 2017

Chen JJ

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7 November 2017

Wang S

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7 November 2017

Savas L

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7 November 2017

London IM

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7 November 2017

Pullman J

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7 November 2017

language of work or name

English

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publication date

1 April 1999

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7 November 2017

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7 November 2017

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7 November 2017

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7 November 2017

page(s)

2507-2517

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Cyclin D1 is a nuclear protein required for cell cycle progression in G1

7 November 2017

cites work

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The retinoblastoma protein pathway and the restriction point

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Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology

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Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

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Identification of c-MYC as a target of the APC pathway

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An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc

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Lessons from hereditary colorectal cancer

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Determinants of translational fidelity and efficiency in vertebrate mRNAs

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Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

21 January 2018

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The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts

21 January 2018

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Monoclonal antibody to cytokeratin for use in routine histopathology

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The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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Translational control of programmed cell death: eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc.

21 January 2018

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Protein synthesis, cell growth and oncogenesis

21 January 2018

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Participation of initiation factors in the recruitment of mRNA to ribosomes

21 January 2018

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Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc

21 January 2018

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Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E

21 January 2018

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Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels

21 January 2018

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Deregulation of protein synthesis as a mechanism of neoplastic transformation

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Upregulated expression of the genes encoding translation initiation factors eIF-4E and eIF-2alpha in transformed cells

21 January 2018

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Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

21 January 2018

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The retinoblastoma protein and cell cycle control

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Coordination between cell growth and cell cycle transit in animal cells

21 January 2018

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What is the restriction point?

21 January 2018

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Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F.

21 January 2018

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Reduction of translation initiation factor 4E decreases the malignancy of ras -transformed cloned rat embryo fibroblasts

21 January 2018

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Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer

21 January 2018

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Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: implications for tumor angiogenesis

21 January 2018

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7 January 2021

Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma

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7 January 2021

Overexpression of cyclin D1 and p53 associated with disease recurrence in colorectal adenocarcinoma

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7 January 2021

Growth Control of Translation in Mammalian Cells

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7 January 2021

Cap-independent translation of heat shock messenger RNAs

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202563

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Dimensions Publication ID

7 November 2017

1024010723

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