Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy (Q42460140)

1 November 2017

title

Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy (English)

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1 November 2017

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1 November 2017

Jeffery D Molkentin

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Joel R Neilson

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Stephanie A Parsons

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1 November 2017

Douglas P Millay

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1 November 2017

Benjamin J Wilkins

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1 November 2017

Orlando F Bueno

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1 November 2017

Gretchen L Tsika

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1 November 2017

Christine M Liberatore

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Gerald R Crabtree

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Richard W Tsika

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language of work or name

English

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publication date

13 April 2004

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Journal of Biological Chemistry

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published in

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volume

279

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1 November 2017

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1 November 2017

page(s)

26192-26200

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Role of calcineurin in striated muscle: development, adaptation, and disease

1 November 2017

cites work

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A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression.

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Calcineurin regulates slow myosin, but not fast myosin or metabolic enzymes, during fast-to-slow transformation in rabbit skeletal muscle cell culture

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Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway

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Altered skeletal muscle phenotypes in calcineurin Aalpha and Abeta gene-targeted mice

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Blockades of mitogen-activated protein kinase and calcineurin both change fibre-type markers in skeletal muscle culture

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A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification

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Calcineurin controls nerve activity-dependent specification of slow skeletal muscle fibers but not muscle growth

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Skeletal muscle hypertrophy is mediated by a Ca2+-dependent calcineurin signalling pathway

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IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1.

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Calcineurin is required for skeletal muscle hypertrophy

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Calcineurin differentially regulates maintenance and growth of phenotypically distinct muscles

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Maintenance of muscle mass is not dependent on the calcineurin-NFAT pathway

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Defective T cell development and function in calcineurin A beta -deficient mice

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Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice

21 January 2018

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All roads lead to Rome: triggering dendritic cell migration

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Identifiers

DOI

10.1074/JBC.M313800200

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1 November 2017

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