MiR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression. (Q42156626)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22119192%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

MiR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression (English)

1 reference

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17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22119192%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jaekwang Kim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22119192%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Hyejin Yoon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22119192%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Sang-Mi Lee

1 reference

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17 January 2020

Hyang-Sook Hoe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22119192%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Carlos Fernández-Hernando

1 reference

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17 January 2020

Jungsu Kim

1 reference

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17 January 2020

language of work or name

English

0 references

publication date

18 November 2011

1 reference

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17 January 2020

published in

Experimental Neurology

1 reference

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17 January 2020

volume

235

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17 January 2020

issue

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17 January 2020

page(s)

476-483

1 reference

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MicroRNA regulation of homeostatic synaptic plasticity

17 January 2020

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Heparan Sulphate Proteoglycan and the Low-Density Lipoprotein Receptor-Related Protein 1 Constitute Major Pathways for Neuronal Amyloid-β Uptake

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MicroRNAs MiR-17, MiR-20a, and MiR-106b act in concert to modulate E2F activity on cell cycle arrest during neuronal lineage differentiation of USSC.

29 May 2018

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ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice

29 May 2018

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Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal trafficking

29 May 2018

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MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice

29 May 2018

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miR-33 links SREBP-2 induction to repression of sterol transporters

29 May 2018

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MiR-33 contributes to the regulation of cholesterol homeostasis.

29 May 2018

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Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons

29 May 2018

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MicroRNA-101 regulates amyloid precursor protein expression in hippocampal neurons

29 May 2018

1 reference

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Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation

29 May 2018

1 reference

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Targeting of mRNAs by multiple miRNAs: the next step

29 May 2018

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Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus

29 May 2018

1 reference

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miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer's disease, inhibits bcl2 translation

29 May 2018

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The role of apolipoprotein E in Alzheimer's disease

29 May 2018

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Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E.

29 May 2018

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microRNA regulation of synaptic plasticity

29 May 2018

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Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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29 May 2018

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MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

29 May 2018

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MicroRNAs can regulate human APP levels.

29 May 2018

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ApoE promotes the proteolytic degradation of Abeta

29 May 2018

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Direct and potent regulation of gamma-secretase by its lipid microenvironment

29 May 2018

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Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

29 May 2018

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The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1.

29 May 2018

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MicroRNAs (miRNAs) in neurodegenerative diseases

29 May 2018

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MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression

29 May 2018

1 reference

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Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.

29 May 2018

1 reference

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The microRNA.org resource: targets and expression

29 May 2018

1 reference

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Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production

29 May 2018

1 reference

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Cholesterol metabolism, apolipoprotein E, adenosine triphosphate-binding cassette transporters, and Alzheimer's disease

29 May 2018

1 reference

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Role of LXR and ABCA1 in the pathogenesis of Alzheimer's disease - implications for a new therapeutic approach.

29 May 2018

1 reference

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Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation

29 May 2018

1 reference

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The Elegance of the MicroRNAs: A Neuronal Perspective

29 May 2018

1 reference

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Abeta42 is essential for parenchymal and vascular amyloid deposition in mice

29 May 2018

1 reference

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Combinatorial microRNA target predictions

29 May 2018

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HDL as a target in the treatment of atherosclerotic cardiovascular disease

29 May 2018

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

29 May 2018

1 reference

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Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

29 May 2018

1 reference

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Expression of Liver X Receptor Target Genes Decreases Cellular Amyloid β Peptide Secretion

29 May 2018

1 reference

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22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion

29 May 2018

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

29 May 2018

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Characterization of four lipoprotein classes in human cerebrospinal fluid

29 May 2018

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Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

29 May 2018

1 reference

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Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis.

29 May 2018

1 reference

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Linking amyloid and tau pathology in Alzheimer's disease: the role of membrane cholesterol in Abeta-mediated tau toxicity.

17 August 2018

1 reference

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Why lipids are important for Alzheimer disease?

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328628

Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328628

Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328628

The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328628

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328628

10.1016/J.EXPNEUROL.2011.11.010

17 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22119192%20AND%20SRC:MED&resulttype=core&format=json

release_46ojs3azgzd65l46oba55h2zxm

17 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/46ojs3azgzd65l46oba55h2zxm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22119192%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

22119192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22119192%20AND%20SRC:MED&resulttype=core&format=json